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Heavy smoking linked with chronic musculoskeletal pain in women

Kentucky women who smoke heavily may experience more chronic musculoskeletal pain, suggests a new study led by University of Kentucky researchers.

29 Sep 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

ACRO releases statement on World Heart Day

The Association of Clinical Research Organizations (ACRO), which represents the global leaders in clinical outsourcing, today released the following statement in recognition of World Heart Day.

29 Sep 2011

Low-tech, inexpensive interventions for bedsores could benefit long-term care residents

Researchers at the University of Toronto have found that low-tech, inexpensive interventions for bedsores could improve health for long-term care residents and reduce health-care costs for the facilities that house them.

29 Sep 2011

Genetic variant may increase severity of coronary artery disease in patients with diabetes

Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes.

29 Sep 2011

Researchers identify 'programmed cell death' pathway in parasitic worms

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's most serious and prevalent diseases.

29 Sep 2011

HHS awards prevention funds with Community Transformation Grants

News outlets report on local winners, how they will use these new resources to promote healthy living and disease prevention and how the funding is sometimes at odds with their leaders' opposition to the health law.

29 Sep 2011

Study reports positive effect of RESPeRATE on CHF patients

InterCure Ltd., a medical device company publicly traded on the Tel-Aviv Stock Exchange, today announced that European Journal of Heart Failure, a peer reviewed medical journal of the European Society of Cardiology, published the results of a 72-patients, randomized, controlled study which demonstrated that device-guided respiratory modulation with RESPeRATE applied at the home setting can significantly relieve symptoms of heart failure in elderly patients.

29 Sep 2011

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.

29 Sep 2011

People with prehypertension have higher risk of experiencing future stroke

People with prehypertension have a 55 percent higher risk of experiencing a future stroke than people without prehypertension, report researchers at the University of California, San Diego School of Medicine in a new meta-analysis of scientific literature published in the September 28 online issue of the journal Neurology.

29 Sep 2011

Researchers use patient's own stem cells to correct genetic alteration that causes SCD

Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

29 Sep 2011

Simple low-cost method for isolation and collection of fragile prostate cancer cells

At the Oct. 2-6 microTAS 2011 conference, the premier international event for reporting research in microfluidics, nanotechnology and detection technologies for life science and chemistry, University of Cincinnati researchers will present a simple, low-cost, method for separating and safely collecting concentrated volumes of fragile prostate cancer cells.

29 Sep 2011

Latest research from world's leading allergists to be presented at ACAAI 2011 meeting

Be among the first to hear the latest research from the world's leading allergists presented at the 2011 annual scientific meeting of the American College of Allergy, Asthma and Immunology (ACAAI), Nov. 3-8, in Boston.

29 Sep 2011

New report finds little evidence to support off-label use of atypical antipsychotics

There is little evidence to support the use of atypical antipsychotic drugs for some treatments other than their officially approved purposes, even though many clinicians continue to commonly prescribe these drugs for so-called "off label" uses, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Salk Institute professor named 2011 recipient of NIH Director's T-R01 program

Dr. Fred Gage, a professor in the Salk Institute Laboratory of Genetics and holder of the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Diseases, has been named a 2011 recipient of the prestigious National Institutes of Health (NIH) Director's Transformative Research Projects (T-R01) program.

29 Sep 2011

Senate gives nod to autism bill

A bill to reauthorize autism-related research and screening programs passed the Senate on Monday night by unanimous consent, ending concerns that programs might expire at the end of the month.

29 Sep 2011

TD2 wins AZBio's Fast Lane award for economic development of Arizona biosciences

TGen Drug Development (TD2) won a Fast Lane award from the Arizona BioIndustry Association (AZBio) for promoting the economic development of Arizona biosciences.

29 Sep 2011

Almirall submits linaclotide MAA to EMA for treatment of IBS-C

Ironwood Pharmaceuticals, Inc. today announced that its European partner Almirall, S.A. submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for linaclotide, a guanylate cyclase type-C (GC-C) agonist, for the treatment of irritable bowel syndrome with constipation.

29 Sep 2011

Prehypertension may increase risk of stroke

Even people with blood pressure that is slightly above normal may be at an increased risk of stroke, according to a review of studies published in the September 28, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Sep 2011