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New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, as well as Type 2 diabetes, according to a new study.

4 Dec 2012

Antidepressants in normal dosage may positively impact mood and seizure frequency

Epilepsy and depression are common co-morbidities. Concern for the potential of certain antidepressants to induce seizures has led to under-treating depression and anxiety disorders in epilepsy patients. Research presented today at the 66th American Epilepsy Society meeting suggests that antidepressants in normal dosage may have a positive impact on both mood and seizure frequency.

4 Dec 2012

Link between smoking, decreased bone density and osteoporosis risk in teenage girls

Teenage girls who smoke accumulate less bone during a critical growth period and carry a higher risk of developing osteoporosis later in life, according to new research in the Journal of Adolescent Health.

4 Dec 2012

Study describes 68 cases of chronic traumatic encephalopathy in athletes, military veterans

A study done by investigators at the Boston University Center for the Study of Traumatic Encephalopathy (CSTE) and the Veterans Affairs Boston Healthcare System, in collaboration with the Sports Legacy Institute (SLI), describes 68 cases of chronic traumatic encephalopathy (CTE) among deceased athletes and military veterans whose brain and spinal cords were donated to the VA CSTE Brain Bank.

4 Dec 2012

Studies explore F-18-FLT PET utility in providing prognostic information for patients with gliomas

In the management of gliomas-or tumors that originate in the brain-precise assessment of tumor grade and the proliferative activity of cells plays a major role in determining the most appropriate treatment and predicting overall survival.

4 Dec 2012

Pipeline embolization device shows promise in treating brain aneurysms

A new technology called the Pipeline embolization device (PED) shows encouraging results in patients with certain types of difficult-to-treat brain aneurysms, reports the December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

4 Dec 2012

Link between stress and brain activation in patients with seizure

A study reported here at the 66th American Epilepsy Society Annual Meeting has identified a significant difference in the brain response to stress in patients who believe stress is an important factor in their seizure control compared to patients who do not hold this belief.

4 Dec 2012

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.

4 Dec 2012

Certain SSRI medications fail to achieve same selectivity for prevention of SUDEP

Scientists from Southern Illinois University today reported the results of a study evaluating the potential effect of two selective serotonin reuptake inhibitors (SSRI) antidepressant medications in reducing the risk of sudden unexpected death in epilepsy (SUDEP).

4 Dec 2012

Researchers discover 15 new genetic regions linked with coronary artery disease

The University of Ottawa Heart Institute (UOHI) participated in the largest genetic study of Coronary Artery Disease (CAD) to date. Researchers from the CARDIoGRAMplusC4D Consortium report the identification of 15 genetic regions newly associated with the disease, bringing to 46 the number of regions associated with CAD risk.

3 Dec 2012

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative.

3 Dec 2012

Prrx1 component prevents cancer cells from lodging in other organs

Researchers discover that the cellular component Prrx1 prevents cancer cells from lodging in other organs and, therefore, generating new focuses of cancer.

3 Dec 2012

Scientists discover new target molecule for development of treatment against Alzheimer's

Scientists from VIB and KU Leuven have discovered a new target molecule for the development of a treatment against Alzheimer's disease. There is currently no cure for this disease.

3 Dec 2012

Obstructive sleep apnea affects women more severely than men

Women suffering from sleep apnea have, on the whole, a higher degree of brain damage than men with the disorder, according to a first-of-its-kind study conducted by researchers at the UCLA School of Nursing.

3 Dec 2012

Merck commences MK-8931 Phase II/III trial in Alzheimer's

Merck, known as MSD outside the United States and Canada, announced it has started a Phase II/III clinical trial designed to evaluate the safety and efficacy of MK-8931 versus placebo in patients with mild-to-moderate Alzheimer's disease.

3 Dec 2012

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

Researchers identify new genetic regions associated with heart attacks

In the largest genetic study of Coronary Artery Disease (CAD) to date, researchers from the CARDIoGRAMplusC4D Consortium report the identification of 15 genetic regions newly associated with the disease, bringing to 46 the number of regions associated with CAD risk.

3 Dec 2012

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité - Universitätsmedizin Berlin and the Université Paris Descartes showed that pain can be successfully treated by targeting immune and nerve cells outside the brain or spinal cord.

3 Dec 2012

Specific transporters could be exploited to deliver toxic substances into cancer cells

Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, the overexpression of specific transporters could be exploited to deliver toxic substances into cancer cells.

3 Dec 2012

NeuroVive announce results from CicloMulsion Phase I trial on cardiac reperfusion injury

NeuroVive announces publication of the results of a Phase I clinical trial of lead product CicloMulsion in the scientific journal Clinical Drug Investigation. The paper highlights that the intravenous cyclosporine formulation CicloMulsion demonstrates bioequivalence and improved tolerability when compared with Sandimmune Injection.

3 Dec 2012

Medical Condition News

New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Antidepressants in normal dosage may positively impact mood and seizure frequency

Link between smoking, decreased bone density and osteoporosis risk in teenage girls

Study describes 68 cases of chronic traumatic encephalopathy in athletes, military veterans

Studies explore F-18-FLT PET utility in providing prognostic information for patients with gliomas

Pipeline embolization device shows promise in treating brain aneurysms

Link between stress and brain activation in patients with seizure

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Certain SSRI medications fail to achieve same selectivity for prevention of SUDEP

Researchers discover 15 new genetic regions linked with coronary artery disease

Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer

Prrx1 component prevents cancer cells from lodging in other organs

Scientists discover new target molecule for development of treatment against Alzheimer's

Obstructive sleep apnea affects women more severely than men

Merck commences MK-8931 Phase II/III trial in Alzheimer's

Diabetes tests: an interview with Dr. Danielle Stowasser

Researchers identify new genetic regions associated with heart attacks

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

Specific transporters could be exploited to deliver toxic substances into cancer cells

NeuroVive announce results from CicloMulsion Phase I trial on cardiac reperfusion injury

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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