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PET scans reveal early signs of Parkinson’s and Lewy body disorders

In a comprehensive Genomic Press perspective article published today, researchers from Fudan University and Shanghai University of Traditional Chinese Medicine have highlighted remarkable advances in the development of positron emission tomography (PET) tracers capable of visualizing α-synuclein aggregates in the brains of patients with Parkinson's disease and related disorders.

29 Apr 2025

Global analysis ties plastic ingredient to soaring heart disease deaths

Daily exposure to certain chemicals used to make plastic household items could be linked to more than 356,000 global deaths from heart disease in 2018 alone, a new analysis of population surveys shows.

29 Apr 2025

Routine molecular monitoring doubles survival in high-risk AML subtypes

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.

29 Apr 2025

Largest study to date reveals high blood sugar accelerates heart damage in healthy youth

In the present study, 1,595 adolescents drawn from the University of Bristol's Children of the 90s cohort were followed up from age 17 until 24 years. To assess the prevalence of prediabetes, which refers to high fasting blood glucose levels, two alternative cutpoints were used, a stricter cutpoint of ≥5.6 mmol/L recommended by the American Diabetes Association, and ≥6.1 mmol/L , which is the present recommendation in many countries.

29 Apr 2025

Uncovering non-clinical risk factors through mendelian randomization

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local environment, offers compelling evidence that improving these unfavorable profiles could prevent up to 63% of SCA cases.

29 Apr 2025

Noninvasive brain modulation using sound waves shows promise for depression and anxiety

Patients suffering from depression, anxiety and trauma-related disorders experienced significant relief from their symptoms after a new treatment that uses sound waves to modulate deep brain activity, according to new research from Dell Medical School at The University of Texas at Austin.

28 Apr 2025

Predictive model could improve treatment decisions for advanced pancreatic cancer patients

Researchers in Japan have developed a predictive model that could improve treatment decisions for advanced pancreatic cancer patients.

28 Apr 2025

Study evaluates long-term outcomes of gamma knife radiosurgery in patients with grade 2 meningiomas

The role of radiosurgery in the treatment of grade 2 meningioma remains unclear. This study aimed to evaluate the long-term outcomes of gamma knife radiosurgery (GKRS) in patients with grade 2 meningiomas and to identify factors influencing tumor control and survival.

28 Apr 2025

New program connects breast cancer patients to exercise and rehab services

A recent randomized controlled trial reveals the potential of a program designed to connect patients who have breast cancer to needed exercise and rehabilitation services starting at diagnosis and throughout care.

28 Apr 2025

New $224 million proton therapy center coming to Penn Presbyterian

Today, Penn Medicine celebrated the groundbreaking of the Roberts Proton Therapy Center at Penn Presbyterian Medical Center in University City, which is expected to open for patient care in late 2027.

28 Apr 2025

Anti-inflammatory drug can prevent and alleviate periodontal tissue damage

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage.

28 Apr 2025

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Neoadjuvant PD-1 blockade with dostarlimab achieved high rates of organ preservation in patients with early-stage mismatch repair-deficient (dMMR) solid tumors across multiple types. Most patients avoided surgery with durable disease control, reshaping potential cancer treatment pathways.

28 Apr 2025

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses.

28 Apr 2025

Insights into the brain's switching mechanism could improve Parkinson's treatment

New USC research offers an unseen insight into how the brain shifts gears. The researchers discovered that our innate ability to make quick changes in motor function are the result of a unique brain mechanism.

28 Apr 2025

UQ begins first human trial of immunotherapy for Type 1 diabetes

Researchers at The University of Queensland have dosed 5 participants in the first clinical trial of a potentially revolutionary immunotherapy drug to treat Type 1 diabetes.

28 Apr 2025

Largest study identifies new genetic targets for osteoarthritis treatment

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

28 Apr 2025

Immune evasion found in early stages of HPV-related anogenital lesions

A new research paper was published in Oncotarget, Volume 16, on April 24, 2025, titled "PD-L1 and FOXP3 expression in high-grade squamous intraepithelial lesions of the anogenital region."

28 Apr 2025

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer – particularly those with specific HER2 mutations – with manageable side effects, according to results from the Phase Ia/Ib Beamion LUNG-1 trial led by researchers from The University of Texas MD Anderson Cancer Center.

28 Apr 2025

New topical gel reduces painful rash from colorectal cancer treatment

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, a common and painful side effect experienced by patients undergoing anti-EGFR therapies for colorectal cancer.

28 Apr 2025

High cannabis use associated with increased colon cancer mortality

Researchers at the University of California San Diego School of Medicine have found that individuals with colon cancer and a documented history of high cannabis use were more than 20 times more likely to die within five years of diagnosis compared to those without such a history.

28 Apr 2025

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Medical Condition News

PET scans reveal early signs of Parkinson’s and Lewy body disorders

Global analysis ties plastic ingredient to soaring heart disease deaths

Routine molecular monitoring doubles survival in high-risk AML subtypes

Largest study to date reveals high blood sugar accelerates heart damage in healthy youth

Uncovering non-clinical risk factors through mendelian randomization

Noninvasive brain modulation using sound waves shows promise for depression and anxiety

Predictive model could improve treatment decisions for advanced pancreatic cancer patients

Study evaluates long-term outcomes of gamma knife radiosurgery in patients with grade 2 meningiomas

New program connects breast cancer patients to exercise and rehab services

New $224 million proton therapy center coming to Penn Presbyterian

Anti-inflammatory drug can prevent and alleviate periodontal tissue damage

Immunotherapy replaces surgery for early-stage dMMR cancers in landmark study

Humanized antibody dismantles metabolic barrier as a potential cancer immunotherapy

Insights into the brain's switching mechanism could improve Parkinson's treatment

UQ begins first human trial of immunotherapy for Type 1 diabetes

Largest study identifies new genetic targets for osteoarthritis treatment

Immune evasion found in early stages of HPV-related anogenital lesions

Targeted drug zongertinib shows strong results for HER2-mutant lung cancer in clinical trial

New topical gel reduces painful rash from colorectal cancer treatment

High cannabis use associated with increased colon cancer mortality

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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