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FDA ODAC recommends approval of Seattle Genetics' ADCETRIS for Hodgkin lymphoma after ASCT

Seattle Genetics, Inc. today announced that the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted 10-0 to recommend that the FDA grant accelerated approval of ADCETRIS™ (brentuximab vedotin) for the treatment of patients with Hodgkin lymphoma who relapse after autologous stem cell transplant (ASCT).

15 Jul 2011

Methods and trends in evaluation of cancer risk

The development of almost all cancer is influenced by environmental factors, argues Dr Günter Obe and co-editors in their new title Cancer Risk Evaluation: Methods and Trends. However, while some environmental factors, such as smoking or ionizing radiation, puts the vast majority of humans at risk regardless of their genetic background, many other risk factors such as hazardous working conditions, increase the cancer risk for smaller groups of the population and are often dependent on additional factors as well as an individual's genetics.

15 Jul 2011

ECG results for young athletes prone to misinterpretation

Pediatric cardiologists are prone to misinterpreting electrocardiograms when using the results to determine whether young athletes have heart defects that could make exercising perilous, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital. This is the first research to examine the acumen of pediatric cardiologists from several health-care institutions in using ECGs to detect rare heart conditions associated with sudden cardiac death.

15 Jul 2011

Experts available to discuss various effects of sun exposure

After many long winter months, Canadians are eager to get outside and enjoy the short and sweet season of warm summer sunshine. Although soaking up the sun can help us forget our winter blues, too much or unprotected exposure can have harmful consequences to your health.

15 Jul 2011

Patients with pulmonary hypertension more likely to have complications after bilateral TKA

A new study by researchers at Hospital for Special Surgery has identified patients who are at a higher risk of morbidity and mortality when undergoing knee replacement surgery in both legs at the same time.

15 Jul 2011

EC grants marketing authorization for Amgen's XGEVA to prevent skeletal-related events

Amgen today announced that the European Commission (EC) has granted marketing authorization for XGEVA (denosumab) for the prevention of skeletal-related events (SREs) in adults with bone metastases from solid tumors.

15 Jul 2011

Scientists analyze structural changes in calcium channels caused by Timothy-mutation

The human genome encodes 243 voltage-gated ion channels. Mutations in calcium channels can cause severe inherited diseases such as migraine, night blindness, autism spectrum disorders and Timothy syndrome, which leads to severe cardiovascular disorders.

15 Jul 2011

Novel combined technique for treating neoplastic meningitis, hydrocephalus

Approximately five to ten percent of patients with primary or metastatic cancer suffer from devastating neurological complications such as headaches, seizures, confusion, difficulty swallowing and visual disturbances. These deficits are caused by a life-threatening form of brain invasion from cancer called neoplastic meningitis.

15 Jul 2011

Study: Bone marrow transplant offers new hope for patients with high-risk leukemia

Bone marrow transplant survival more than doubled in recent years for young, high-risk leukemia patients treated at St. Jude Children's Research Hospital, with patients who lacked genetically matched donors recording the most significant gains. The results are believed to be the best ever reported for leukemia patients who underwent bone marrow transplantation.

15 Jul 2011

IBM, Coriell partner to explore personalized medicine

IBM today announced that Coriell Institute for Medical Research, the largest biobank of living human cells, is using IBM technology to advance its research of human genetic disease and to more efficiently maintain its massive collection of biological resources.

15 Jul 2011

Family doctors misdiagnose 31.7% of coronary heart disease: Study

Of 180 patients in this study in whom a reference committee later identified coronary heart disease (CHD), 31.7% had originally been misdiagnosed by their family doctors as not having CHD.

15 Jul 2011

FDA asks Guided Therapeutics to provide additional information on LuViva PMA

Guided Therapeutics, Inc., developer of a rapid and painless biophotonic testing platform for the early detection of cancer, today announced that, after a series of meetings with the U.S. Food and Drug Administration (FDA), and after reviewing draft responses, the FDA has asked the company to provide additional information in the company's response to one remaining question.

15 Jul 2011

Study: Overall awareness about eye health lower among ethnic Americans

The results of recent, comprehensive research supported by Transitions Optical revealed that the majority of Americans are not taking the proper steps to care for the health of their eyes, and that awareness of both short- and long-term effects of UV exposure on vision is remarkably low.

15 Jul 2011

CDC investigators working to understand nodding syndrome among East African children

Nature News examines the work of a CDC team working in South Sudan, Tanzania, and Uganda to investigate nodding syndrome, "a poorly understood and seemingly growing problem in eastern Africa."

15 Jul 2011

Rcadia reports promising results from calcium scoring cCTA trial

Rcadia Medical Imaging has achieved proof-of-concept with the first fully automated software that performs calcium scoring directly from a coronary CT angiography (cCTA) study.

15 Jul 2011

IQWiG finds no differences between two treatment strategies for type 2 diabetes

Whether patients with type 2 diabetes mellitus benefit from attempts to lower their blood glucose levels to near-normal levels through treatment remains an unanswered question. The studies currently available provide indications of a benefit but also of potential harm.

15 Jul 2011