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Presence of SPDEF protein may predict prostate cancers that are unable to metastasize

Prostate cancer doesn't kill in the prostate - it's the disease's metastasis to other tissues that can be fatal. A University of Colorado Cancer Center study published this week in the Journal of Biological Chemistry shows that prostate cancer cells containing the protein SPDEF continue to grow at the same pace as their SPDEF- cousins, but that these SPDEF+ cells are unable to survive at possible sites of metastasis.

8 Jul 2012

Extra weight not necessarily linked with higher risk of death

An evaluation of national data by UC Davis researchers has found that extra weight is not necessarily linked with a higher risk of death.

7 Jul 2012

Dynorphin plays an important role in weakening anxiety

Feelings of anxiety very effectively prevent people from getting into situations that are too dangerous. Those who have had a terrible experience initially tend to avoid the place of tragedy out of fear. If no other oppressive situation arises, normally the symptoms of fear gradually subside.

7 Jul 2012

SAGE sponsors symposium on cardiovascular disease prevention

European experts in cardiovascular medicine will today gather at a two day symposium to address the national agenda on cardiovascular disease prevention, held at Imperial College London and sponsored by leading independent academic and professional publisher SAGE.

7 Jul 2012

Study reveals connection among sugar, cancer, and dependence on breathing machines

A new research report published online in the FASEB Journal reveals a connection among sugar, cancer, and dependence on breathing machines--microRNA-320a.

7 Jul 2012

Key difference between spinal regeneration in fish and mammals

Yona Goldshmit, Ph.D., is a former physical therapist who worked in rehabilitation centers with spinal cord injury patients for many years before deciding to switch her focus to the underlying science.

7 Jul 2012

Protein AMPK protects sensory cells in the inner ear from permanent damage

If you're concerned about losing your hearing because of noise exposure (earbud deafness syndrome), a new discovery published online in the FASEB Journal offers some hope. That's because scientists from Germany and Canada show that the protein, AMPK, which protects cells during a lack of energy, also activates a channel protein in the cell membrane that allows potassium to leave the cell.

7 Jul 2012

New strategy to reduce or eliminate scars on the skin

Whether from surgery or battle wounds, ugly scars can affect body and mind. Now a new research report appearing online in the FASEB Journal offers a new strategy to reduce or eliminate scars on the skin.

7 Jul 2012

New epigenetic path toward a cure for osteoarthritis

In what could be a breakthrough in the practical application of epigenetic science, U.K. scientists used human tissue samples to discover that those with osteoarthritis have a signature epigenetic change (DNA methylation) responsible for switching on and off a gene that produces a destructive enzyme called MMP13.

7 Jul 2012

Biological mechanisms behind appetite-suppressing effects of proteins

Frequently recommended in weight-loss diets, dietary proteins have proven effectiveness thanks to their appetite-suppressing effects. A team led by Gilles Mithieux, Director of Inserm's Unit 855 "Nutrition and the Brain" in Lyon, has managed to explain the biological mechanisms behind these properties.

7 Jul 2012

Cystic fibrosis patient receives generous 'gift of life'

Meara Schmidt, 28, almost died a few weeks ago. Lying in her hospital bed at UCLA, the seriously ill cystic fibrosis patient felt herself slipping away and her life flashing by. But then the image of her husband appeared, and she knew she was not ready to go.

7 Jul 2012

Safe optimal concentration of propolis against radiation-induced damage

Researchers determined the amount of propolis offering maximum protection against ionised radiations without being toxic to blood cells.

7 Jul 2012

New Gateway-funded phase II ADAPT study for metastatic colorectal cancer

The Gateway for Cancer Research announces an exciting new Gateway-funded phase II study using ADAPT therapy for treatment of metastatic colorectal cancer based on a 2010 AACR presentation by Dr. Lin and his collaborators.

7 Jul 2012

FDA approves KRAS gene mutation test for colorectal cancer

The U.S. Food and Drug Administration today approved the first genetic test that can help some colorectal cancer (CRC) patients and their doctors determine if the drug Erbitux (cetuximab) would be an effective treatment based on the absence of a gene mutation. The therascreen KRAS RGQ PCR Kit can provide information about the KRAS gene mutation in patients whose CRC has spread to other parts of their body (metastasized).

7 Jul 2012

New optical microscope identifies rare breast cancer cells

The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments.

7 Jul 2012

DTU develops new computer model for AAA rupture risk evaluation

A new computer model is expected to assist the medical doctors in saving patients with this potential life threatening condition. Assistant Professor Marie Sand Enevoldsen at the Technical University of Denmark (DTU) has developed a prototype computer model for AAA rupture risk evaluation.

6 Jul 2012

NYU Langone completes first year of robotic mitral valve repair program

The Cardiothoracic Surgery Department at NYU Langone Medical Center completed its first year of offering patients endoscopic robotic mitral valve repair surgery. This procedure was introduced at the medical center in the spring of 2011 by Dr. Didier F. Loulmet, a renowned cardiothoracic surgeon who helped develop the procedure.

6 Jul 2012