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New HS44 molecule inhibits lung metastasis

One type of white blood cell, the Natural Killer T Cells, fights against infections and tumours by freeing cytokine proteins which activate the body's immune response and destroy infected or malignant cells. To do so they must receive an activation signal. Specific receptors located on their surface act as switches: they activate the lymphocyte in presence of an antigen, a molecule which triggers alarm signals.

2 Mar 2012

AJPM&R releases new iPad app for physical medicine and rehabilitation specialists

Ninety years after its first issue, American Journal of Physical Medicine & Rehabilitation has announced the latest step in its evolution with the release of the new AJPM&R for the iPad app.

2 Mar 2012

Study offers hope for novel approach to prevent AD

As scientists struggle to find an effective way to prevent Alzheimer's disease, researchers at the University of Wisconsin-Madison may have found a new approach to interrupting the process that leads to the devastating disease.

2 Mar 2012

New link between polyamine regulation and ESC biology

A*STAR scientists have for the first time, identified that precise regulation of polyamine levels is critical for embryonic stem cell (ESC) self-renewal - the ability of ESCs to divide indefinitely - and directed differentiation.

2 Mar 2012

Bariatric surgery safe for CKD patients with obesity

Weight-loss surgery is safe for chronic kidney disease (CKD) patients who are obese, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

2 Mar 2012

Report highlights benefits of Nuvilex's cell encapsulation technology for diabetes

Nuvilex, Inc., an emerging biotechnology provider of cell and gene therapy solutions, today provided additional details based on the Goldman Small Cap Research report issued February 29, 2012, that highlighted the company's cell encapsulation technology and its benefits for treating chronic diseases such as diabetes.

2 Mar 2012

SuperFAK protein decreases damage from heart attack by 50%

Researchers from the University of North Carolina at Chapel Hill reduced damage from a heart attack by 50 percent by enhancing a protective protein found in mice and humans.

2 Mar 2012

Study uncovers how FoxO1 protein contributes to heart disease in patients with diabetes

UT Southwestern Medical Center cardiologists have uncovered how a specific protein's previously unsuspected role contributes to the deterioration of heart muscle in patients with diabetes. Investigators in the mouse study also have found a way to reverse the damage caused by this protein.

2 Mar 2012

Methylnaltrexone may restore bowel function in critically ill patients

Opioids are a mainstay of care in the critical care unit, but their use frequently causes constipation which can lead to adverse outcomes including delayed feeding and later discharge from the ICU. Researchers from London, UK, and Chicago, IL, have found that methylnaltrexone (MNTX), a peripheral opioid antagonist, may restore bowel function in critically ill patients.

2 Mar 2012

Serum taurine may protect against CHD in women with high cholesterol

A nutrient found in the dark meat of poultry may provide protection against coronary heart disease (CHD) in women with high cholesterol, according to a study by researchers at NYU Langone Medical Center.

2 Mar 2012

Alternative subunits generate different functional subtypes of RNA polymerases

Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case protein subunits -- used to assemble those machines.

2 Mar 2012

HNSF, AAO publish new guideline on sudden hearing loss

On March 1, 2012, the American Academy of Otolaryngology-Head and Neck Surgery Foundation published a new Clinical Practice Guideline on Sudden Hearing Loss (SHL). This guideline is published as a supplement to Otolaryngology-Head and Neck Surgery.

2 Mar 2012

Induced hyperammonaemia increases daytime sleepiness in patients with cirrhosis

Italian and Swiss researchers confirm that induced hyperammonaemia significantly increases daytime sleepiness in patients with cirrhosis. The findings available in the March issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, show that higher blood levels of ammonia reduced the ability of cirrhotic patients to produce restorative sleep.

2 Mar 2012