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Closing the 'cancer divide' between developing and developed countries

Noting "there is a huge 'cancer divide' between rich and poor," with more than half of new cancer cases and almost two-thirds of all cancer deaths occurring in developing countries, this year's World Cancer Day theme, "Together It Is Possible," "calls on all individuals, organizations and governments to do their part to reduce premature deaths from cancers by 25 percent by 2025," Felicia Knaul, secretariat for the Global Task Force on Expanded Access to Cancer Care and Control in Developing Countries, and Jonathan Quick, president of Management Sciences for Health, write in a Huffington Post opinion piece.

7 Feb 2012

Cyclin D1 oncogene may promote chromosomal instability

A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of Cancer Biology, have shown in a study published online Feb. 6 in the Journal of Clinical Investigation that the oncogene cyclin D1 may promote a genetic breakdown known as chromosomal instability (CIN). CIN is a known, yet poorly understood culprit in tumor progression.

7 Feb 2012

Study may explain why women have higher rate of ACL injuries than men

Much orthopaedic research has been devoted to determining why women are far more susceptible to knee ligament injuries than men. According to a new study, the answer may lie in geometry - the length and shape of a patient's knee bone - more than gender.

7 Feb 2012

Inhibiting MET signaling in glioblastoma has major therapeutic value

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans.

7 Feb 2012

Novel stem-cell technique to enhance bone growth

A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body's stem cells to travel to the surface of bones.

7 Feb 2012

Short spinning session can induce troponin T in healthy people

A short spinning session can trigger the same biochemical indications as a heart attack - a reaction that is probably both natural and harmless, but should be borne in mind when people seek emergency treatment for chest pain, reveals a study from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

7 Feb 2012

GOP candidates: Santorum backs 'discredited' stroke claim, he and Gingrich continue attacks on 'Romneycare'

As the GOP presidential hopefuls continue sparring on the campaign trail, The Associated Press takes a look at the "influence game" and tracks how big donors pursue their policy desires. Meanwhile, House Democrats are betting that Medicare will be the issue that wins them control of their chamber.

7 Feb 2012

Study to understand how brain processes information in competitive settings

Researchers have found a way to study how our brains assess the behavior - and likely future actions - of others during competitive social interactions. Their study, described in a paper in the Proceedings of the National Academy of Sciences, is the first to use a computational approach to tease out differing patterns of brain activity during these interactions, the researchers report.

7 Feb 2012

Karolinska Institutet to study fundamental causes of diabetes

The Swedish medical university, Karolinska Institutet, has received a grant of 1.6 million Euro from the Stichting af Jochnick Foundation for research into the fundamental causes of diabetes. The grant will make it possible to use unique methods to study how the release of insulin is regulated in living organisms - and this will create new opportunities for developing more effective drugs against diabetes.

7 Feb 2012

New blood-thinning drugs likely to replace Coumadin for patients with non-valvular AF

Within a few years, a new generation of easy-to-use blood-thinning drugs will likely replace Coumadin for patients with irregular heartbeats who are at risk for stroke, according to a journal article by Loyola University Medical Center physicians.

7 Feb 2012

First European CPGs for diagnosis and management of Wilson's disease

The first European Clinical Practice Guidelines (CPGs) for the diagnosis and management of Wilson's disease are published today by the European Association for the Study of the Liver (EASL) on the EASL website.

7 Feb 2012

Book focuses on Group Schema Therapy for BPD

Therapists, patients and families dealing with Borderline Personality Disorder now have an unprecedented guide to a way out of the misery and chaos in the form of the soon to be release book "Group Schema Therapy for Borderline Personality Disorder: Treatment Manual and Patient Workbook".

7 Feb 2012

Epilepsy surgery improves QOL and long-term seizure control

While epilepsy surgery is a safe and effective intervention for seizure control, medical therapy remains the more prominent treatment option for those with epilepsy. However, a new 26-year study reveals that following epilepsy surgery, nearly half of participants were free of disabling seizures and 80% reported better quality of life than before surgery.

7 Feb 2012

BPS Annual Meeting to be held Feb. 25 - 29 in San Diego

The latest news and discoveries in medicine, physics, environmental science, and interdisciplinary fields will be featured at the 56th Annual Meeting of the Biophysical Society (BPS), held Feb. 25 - Feb. 29, 2012, at the San Diego Convention Center in San Diego, Calif. With more than 4,000 poster presentations, 200 exhibits, 20 symposia, and 6,000 research scientists in attendance each year, the BPS Annual Meeting is the largest meeting of biophysicists in the world.

7 Feb 2012

Low-dose MNC hUCB therapy effective in ALS-modeled mice

Repeated, low-dose injections of mononuclear cells derived from human umbilical cord blood have been found effective in protecting motor neuron cells, delaying disease progression and increasing lifespan for mice modeling amyotrophic lateral sclerosis, or ALS, also referred to as Lou Gehrig's disease, report University of South Florida researchers and colleagues from Saneron CCEL Therapeutics, Inc., and the Ribeirao Preto School of Medicine at the University of Sao Paulo, Brazil.

7 Feb 2012

New ACCP guidelines address DVT/PE risk factors for long-distance travel

New evidence-based guidelines from the American College of Chest Physicians (ACCP) address the many risk factors for developing a deep vein thrombosis (DVT), or blood clot, as the result of long-distance travel.

7 Feb 2012

Breathalyzer distinguishes normal and disease-state glucose metabolism

The future of disease diagnosis may lie in a "breathalyzer"-like technology currently under development at the University of Wisconsin-Madison.

7 Feb 2012

New scoring method helps predict functional outcomes in stroke

A new scoring method can help doctors quickly decide which stroke patients will respond well to the clot-busting drug alteplase, according to a study published in the February 7, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

7 Feb 2012

Queen's study aims to improve end of life decision making among elderly

At a time when there is tremendous concern about the utilization of technology at the end of life and the costs of technology, the Canadian Institutes of Health Research (CIHR) has funded a multi-center study aimed to improve end of life decision making amongst seriously ill, elderly hospitalized patients. Queen's University is one institution receiving funding for this initiative.

7 Feb 2012

EpiCept seeks FDA Fast Track designation for AmiKet to treat CIPN

EpiCept Corporation today announced that it has filed for Fast Track designation for AmiKet(amitriptyline 4%, ketamine 2% cream) for the treatment for chemotherapy-induced peripheral neuropathy (CIPN) with the U.S. Food and Drug Administration.

7 Feb 2012