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Prion protein uptake associated with development of Scrapie disease

Scrapie is a neurodegenerative disease which can function as a model for other diseases caused by an accumulation of proteins resulting in tissue malformations (proteinpathies), such as Alzheimer's and Parkinson's disease.

30 Dec 2011

Free, low-cost strategies to maintain good health in the new year

With the start of a new year, Dana-Farber Cancer Institute experts are encouraging people to ring in new healthy habits and offer a number of free and low-cost strategies to help people maintain good health and possibly reduce various cancer risks.

29 Dec 2011

Silent strokes linked to memory loss in the elderly

New research links 'silent strokes,' or small spots of dead brain cells, found in about one out of four older adults to memory loss in the elderly. The study is published in the January 3, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

29 Dec 2011

Substance-related health problems during rave parties: Study

In a study of 3.8 million attendees to 249 raves over 12 years, researchers found that almost 27,897 people visited a first aid station, and more than a third (10,100) reported a substance-related problem.

29 Dec 2011

New form of esophagectomy for treatment of severe cancer

Surgeons at Mayo Clinic in Arizona have perfected a new procedure that offers a less invasive option in the treatment of one of the most severe cancers.

29 Dec 2011

OAC and Obesity PPM to launch long-term online educational initiative

In January 2012, the OAC and Obesity PPM will launch a long-term online educational initiative to increase understanding of the complexity of obesity and its many causes. The disease of obesity impacts individuals physically, emotionally, economically and socially. This initiative will look at various factors, both controllable and uncontrollable, impacting individuals affected by obesity.

29 Dec 2011

Chart trends for bone and mineral metabolism in CKD

BioTrends Research Group, LLC has released findings from the 2011 ChartTrends: Bone and Mineral Metabolism in Chronic Kidney Disease report, the fifth in an on-going annual series. The study was conducted with 204 U.S. nephrologists who completed detailed chart reviews for 1,037 patients in CKD Stage 3, 4 and 5 not yet on dialysis.

29 Dec 2011

Seniors with higher levels of vitamins and omega 3 fatty acids perform better on mental acuity tests

New research has found that elderly people with higher levels of several vitamins and omega 3 fatty acids in their blood had better performance on mental acuity tests and less of the brain shrinkage typical of Alzheimer's disease - while "junk food" diets produced just the opposite result.

29 Dec 2011

New initiative to detect cancers in earliest stages inside cells

A team of cancer imaging experts at Johns Hopkins has embarked on a five-year research initiative to speed development of early diagnostic tests and new treatments for breast, prostate and other common cancers.

29 Dec 2011

Diets high in vitamins or omega 3 fatty acids reduce brain shrinkage

People with diets high in several vitamins or in omega 3 fatty acids are less likely to have the brain shrinkage associated with Alzheimer's disease than people whose diets are not high in those nutrients, according to a new study published in the December 28, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

29 Dec 2011

Emergent commences Phase 2 combination trial of TRUw-016 with bendamustine in relapsed CLL

Emergent BioSolutions Inc. today announced the initiation of a Phase 2 study (protocol 16201) of TRU-016 in combination with bendamustine for patients with relapsed chronic lymphocytic leukemia (CLL).

29 Dec 2011

Troponin I level test may help rule-out diagnosis of heart attack

For patients admitted to an emergency department with chest pain, use of a contemporary or highly sensitive test for levels of troponin I (a protein in muscle tissue) may help rule-out a diagnosis of heart attack, while changes in the measured levels of this biomarker at 3 hours after admission may be useful to confirm a diagnosis of heart attack, according to a study in the December 28 issue of JAMA.

28 Dec 2011

Research provides first proof of epigenetic risk factor for type 2 diabetes

Research carried out at the Hebrew University of Jerusalem has provided the first proof of molecular risk factors leading to type 2 diabetes, providing an "early warning" sign that could lead to new approaches to treating this and other human disease conditions.

28 Dec 2011

Vejthani Hospital Bangkok offers High Tibial Osteotomy Surgery for osteoarthritis

Vejthani Hospital Bangkok offers a High Tibial Osteotomy Surgery for osteoarthritis at TJR Center. The procedure prolongs the life of a damaged knee, helps relieve pain in the knee and delays the need for a total knee replacement.

28 Dec 2011

Scientists identify molecular player critical to proper working of important health proteins

Half the drugs used today target a single class of proteins - and now scientists have identified an important molecular player critical to the proper workings of those proteins critical to our health.

28 Dec 2011

Meta-analysis does not find significant association between CYP2C19 genotype and cardiovascular events

Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may be less responsive to the medication, a review and analysis of previous studies did not find an overall significant association between the CYP2C19 genotype and cardiovascular events.

28 Dec 2011

Obesity associated with hypothalamic injury

The number of people who suffer from one or more of the adverse complications of obesity, including type 2 diabetes and heart disease is rapidly increasing. Thus far, drugs designed to treat obesity have shown limited efficacy and have been associated with serious side effects.

28 Dec 2011

DNA stays too tightly wound in brain cells of patients with schizophrenia

Scientists at The Scripps Research Institute have discovered that DNA stays too tightly wound in certain brain cells of schizophrenic subjects. The findings suggest that drugs already in development for other diseases might eventually offer hope as a treatment for schizophrenia and related conditions in the elderly.

28 Dec 2011

Celiac disease may increase risk of disordered eating, depression in women

Women with celiac disease -- an autoimmune disorder associated with a negative reaction to eating gluten -- are more likely than the general population to report symptoms of depression and disordered eating, even when they adhere to a gluten-free diet, according to researchers at Penn State, Syracuse University and Drexel University.

28 Dec 2011

IL-1 gene inactivation may reduce severe clinical complications of atherosclerosis

Atherosclerosis is a disease of the major arterial blood vessels. It is one of the major causes of heart attack and stroke. The proinflammatory molecule IL-1 has been linked to atherosclerosis and a clinical trial has been launched in which an antibody specific for IL-1-beta is being studied for its effects on the severe clinical complications of atherosclerosis.

28 Dec 2011