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IRB approves Revolutions Medical's MRI software tools

Revolutions Medical Corporation is happy to report that it has received notice that Investigational Review Board approval has been granted this month to the Philadelphia College of Osteopathic Medicine for the research project application titled 'Characterization of Intracranial Hemorrhages by Color MRI Automatic Segmentation,' by Dr. H. Keith Brown and his collaborators.

13 Jan 2011

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Beth Israel Deaconess Medical Center cancer geneticist Pier Paolo Pandolfi, MD, PhD, is the recipient of the 2011 Pezcoller Foundation-AACR (American Association of Cancer Research) International Award for Cancer Research.

13 Jan 2011

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

Pfizer Inc. announced today that it has initiated the rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for crizotinib (PF-02341066), an oral first-in-class anaplastic lymphoma kinase (ALK) inhibitor for the treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumors are ALK-positive. Pfizer expects to complete the submission in the first half of 2011.

13 Jan 2011

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

New research has found one of the smallest entities in the human genome, micro-RNA, could increase the risk of limb amputation in diabetic patients who have poor blood flow.

13 Jan 2011

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

Eli Lilly and Company announced the U.S. Food and Drug Administration (FDA) Gastrointestinal Drugs Advisory Committee voted today to recommend non-approval of liprotamase, a non-porcine pancreatic enzyme replacement therapy (PERT), currently under FDA review for the treatment of exocrine pancreatic insufficiency (EPI).

13 Jan 2011

New discovery has brought dream of transforming measles virus against cancer

When most people in the developed world think of measles, what comes to mind is only a dim memory of a vaccination at a pediatrician's office. But while childhood vaccination has virtually eliminated measles from North America and much of Europe, researchers remain interested in the virus.

13 Jan 2011

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Some disorders of the brain are obvious - the massive death of brain cells after a stroke, the explosion in the growth of cells that marks a tumor. Other disorders, such as autism, schizophrenia and mental retardation show no physical signs of damage and are believed to be caused by problems in how brain cells communicate with one another.

13 Jan 2011

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Though the cause of Alzheimer's disease still is unknown, recent studies have implicated three proteins strongly in its onset. New research from the University of Alabama at Birmingham, the Gladstone Institutes and the Baylor College of Medicine indicates that interactions between those three proteins might lead to brain dysfunction and AD in a mouse model of the disease.

13 Jan 2011

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

13 Jan 2011

Obesity in children today may contribute to 2-5 year decline in life expectancy

For the first time in history, the next generation will not live longer, or even as long, as their parents. "Diseases such as Type II diabetes, high blood pressure, heart conditions and joint deterioration - what were once considered 'adult' diseases - are regularly being diagnosed in children, due to the prevalence of obesity," said Jessica Bartfield, MD, internal medicine and medical weight-loss specialist at Gottlieb Memorial Hospital, part of the Loyola University Health System.

13 Jan 2011

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

A team of researchers from the Peninsula College of Medicine and Dentistry are part of a wider group of researchers from leading institutions that will implement a -4.7m Policy Research Unit dedicated to achieving early cancer screening and diagnosis. The funding is provided over five years by the Department of Health and will be led by Queen Mary, University of London.

13 Jan 2011

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

MedImmune, the global biologics unit of AstraZeneca PLC and Micromet, today announced the initiation of a Phase 1 trial of MEDI-565 in patients with advanced gastrointestinal cancers. MEDI-565 is a BiTE antibody designed to direct a patient's T cells, the body's most potent killer cells, against cancer cells that express carcinoembryonic antigen.

13 Jan 2011

FDA accepts to review Fibrocell Science's azficel-T drug

Fibrocell Science, a biotechnology company focused on the development of autologous cell therapies for aesthetic, medical and scientific applications, announced today that the U.S. Food & Drug Administration has accepted for review the Company's complete response submission for azficel-T, proposed brand name laViv, for the treatment of moderate to severe nasolabial folds and wrinkles.

12 Jan 2011

New ultrasound elastography can help predict cancer in patients with BI-RADS category 4 masses

A new ultrasound technique is proving valuable in distinguishing malignant from benign breast lesions in some patients - results that could mean fewer unnecessary breast biopsies, a new study shows.

12 Jan 2011

AstraZeneca, CANCER RESEARCH UK enter strategic alliance to conduct experimental cancer drug trials

CANCER RESEARCH UK's drug development office has signed a Strategic Combinations Alliance with AstraZeneca to take combinations of experimental cancer drugs into early phase clinical trials.

12 Jan 2011

GSK, ChemoCentryx initiate '786 Phase III clinical trial for Crohn's disease

GlaxoSmithKline and ChemoCentryx, announced today that the first patient with Crohn's disease has initiated treatment in the initial pivotal induction study comparing Traficet-EN, now designated GSK1605786 ('786), to placebo.

12 Jan 2011

Study indicates disease's underlying causes in mice, finds compounds that normalize Alzheimer's brain

A Blanchette Rockefeller Neurosciences Institute study published today in the Journal of Neuroscience reveals underlying causes for the degeneration of synapses in Alzheimer's Disease and identifies promising pharmaceutical solutions for the devastating condition that affects more than 5 million people in the United States.

12 Jan 2011

FDA panel rejects new pancreatic enzyme replacement drug

Eli Lilly & Co did not win the support of the U.S. advisory panel on Wednesday for its one-of-its kind drug not made from pig enzymes to help certain pancreatic patients digest food. A Food and Drug Administration panel of outside experts in a 7-4 vote said they were not convinced the experimental medicine, known chemically as liprotamase, worked well enough for patients to absorb enough needed nutrients. One member of the panel abstained.

12 Jan 2011

Antibiotics for ear infection in kids better than watchful waiting: Study

Findings from two latest clinical trials reveal that a young child with ear infections recovers faster and more completely if doctors give antibiotics right away rather than waiting to see if the kid get better on his/her own. One of the studies was in the U.S. and one in Finland. Earlier it has been debated that for young children with middle ear infections or otitis media whether immediate antibiotic treatment was better than watchful waiting. Current treatment recommendations in the U.S., Canada, and Europe allow for a watch-and-wait approach to suspected middle ear infections in young children. Change is coming, predicts study leader Alejandro Hoberman, MD, of Children’s Hospital of Pittsburgh.

12 Jan 2011

New Down syndrome non-invasive test for ‘mums-to-be’ on the horizon

According to experts a simple DNA test for Down syndrome could save nearly all pregnant women from invasive tests like amniocentesis. Usually 3% to 5% of pregnant women in the UK or some 30,000 women have to undergo invasive tests like amniocentesis that increases the risk of miscarriage to 1%. The new DNA blood test could bring this down to 0.1%, according to a study in the British Medical Journal.

12 Jan 2011

Medical Condition News

IRB approves Revolutions Medical's MRI software tools

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Pfizer initiates rolling submission of crizotinib NDA for ALK-positive advanced NSCLC

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

New discovery has brought dream of transforming measles virus against cancer

UCLA imaging system could help reveal 'miscommunications' in autism, schizophrenia

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

Obesity in children today may contribute to 2-5 year decline in life expectancy

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

Micromet, MedImmune initiate MT111 Phase 1 trial in patients with advanced gastrointestinal cancer

FDA accepts to review Fibrocell Science's azficel-T drug

New ultrasound elastography can help predict cancer in patients with BI-RADS category 4 masses

AstraZeneca, CANCER RESEARCH UK enter strategic alliance to conduct experimental cancer drug trials

GSK, ChemoCentryx initiate '786 Phase III clinical trial for Crohn's disease

Study indicates disease's underlying causes in mice, finds compounds that normalize Alzheimer's brain

FDA panel rejects new pancreatic enzyme replacement drug

Antibiotics for ear infection in kids better than watchful waiting: Study

New Down syndrome non-invasive test for ‘mums-to-be’ on the horizon

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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