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Insight into how brain organizes during development

Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. The findings, published in the Journal of Comparative Neurology today, describe - in more detail than ever before - the consequences of the loss of a key molecule involved in establishing proper brain architecture during brain development.

3 Aug 2011

Posttraumatic stress disorder linked to persistent fears of recurrent SAH

One-third of patients who have survived a life-threatening subarachnoid hemorrhage (SAH) have disabling symptoms of posttraumatic stress disorder (PTSD), reports a study in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

3 Aug 2011

Alcohol, tobacco use increase risk of upper aero-digestive tract cancers

Upper aero-digestive tract cancers (UADT), especially those of the oral cavity, pharynx, and larynx, are often referred to as alcohol-related cancers as it has been shown repeatedly that heavy drinkers, in particular, are at increased risk.

3 Aug 2011

Mood-related brain protein linked to sadness during cigarette withdrawal

Heavy smokers may experience sadness after quitting because early withdrawal leads to an increase in the mood-related brain protein monoamine oxidase A (MAO-A), a new study by the Centre for Addiction and Mental Health (CAMH) has shown. This finding, which was published in the Archives of General Psychiatry, may also explain why heavy smokers are at high risk for clinical depression.

3 Aug 2011

Double-lung transplant survivor stays busy since retirement

Fewer than half of lung transplant patients survive for five years. But nearly 14 years after receiving a double-lung transplant at Loyola University Medical Center, Damian Neuberger's lungs continue to function normally. He breathes easily while walking four or five miles a day.

3 Aug 2011

Combination of six common QA measures could prevent radiotherapy errors

A combination of several well-known safety procedures could greatly reduce patient-harming errors in the use of radiation to treat cancer, according to a new study led by Johns Hopkins researchers.

3 Aug 2011

Biomoda to receive European patent for porphyrin-based compound to detect cancer

Cancer diagnostics company Biomoda, Inc. received notification from the European Patent Office of its intention to grant the company's patent application related to a method of using Biomoda's proprietary porphyrin-based compound to detect cancer and pre-cancerous cells in body fluid and tissue samples.

3 Aug 2011

Biotica acquires full rights to rapamycin analogue program from Pfizer

Biotica Technology Ltd. today announced that it has regained full rights from Pfizer Inc. to its rapamycin analogue program, including transfer of data and materials.

3 Aug 2011

Researchers sample hydrogenotrophic microbes in the healthy human colon

They make up less than one-hundredth of 1 percent of the microbes that live in the colon, but the bacteria and archaea that sop up hydrogen in the gut are fundamental to colon health. In a new study, researchers take a first look at these "hydrogenotrophic" microbes, mapping where they live and how abundant they are in different parts of the lower intestine.

3 Aug 2011

Better communication needed between caregivers and their relatives with dementia

Caregivers and their relatives who suffer from mild to moderate dementia often have different perceptions regarding the amount and quality of care given and received. A study by researchers at Penn State and the Benjamin Rose Institute on Aging examined a major source of those differences -- caregivers do not understand the things that are important to their relatives with dementia.

3 Aug 2011

Risperidone does not appear to reduce military-related PTSD symptoms

Patients with military-related, chronic posttraumatic stress disorder (PTSD) and symptoms that were not improved with use of an antidepressant medication did not experience a reduction in PTSD symptoms with use of the antipsychotic medication risperidone, according to a study in the August 3 issue of JAMA, a theme issue on violence and human rights.

3 Aug 2011

Eating legumes, brown rice and dried fruit may decrease risk of colorectal cancer

Eating legumes at least three times a week and brown rice at least once a week was linked to a reduced risk of colon polyps by 33 percent and 40 percent respectively, according to Loma Linda University research recently published in Nutrition and Cancer.

3 Aug 2011

Study evaluates humor and laughter in patients with COPD

Having a sense of humor is associated with improved emotional functioning and an enhanced quality of life among patients with a chronic lung illness, but the actual act of laughing out loud can reduce lung function, at least in the short term, research suggests.

3 Aug 2011

Negative physiological changes may raise risk of type 2 diabetes

According to the Centers for Disease Control and Prevention, 25 percent of Americans have inactive lifestyles and 75 percent do not meet the weekly exercise recommendations to maintain good health.

3 Aug 2011

VIB researchers develop mouse model for Charcot-Marie-Tooth neuropathy

VIB researchers have developed a mouse model for Charcot-Marie-Tooth (CMT) neuropathy, a hereditary disease of the peripheral nervous system.

3 Aug 2011

Lifestyle factors of people with exceptional longevity

People who live to 95 or older are no more virtuous than the rest of us in terms of their diet, exercise routine or smoking and drinking habits, according to researchers at Albert Einstein College of Medicine of Yeshiva University.

3 Aug 2011

New alternative to immunosuppressive treatment after kidney transplants without severe side effects

There is now a new alternative to immunosuppressive treatment after kidney transplants which comes without the usual severe side effects. The Medical University was significantly involved in the clinical development of the active ingredient Belatacept and a suitable preparation has now been given EU-wide authorisation.

3 Aug 2011

Federal appeals court partially reverses ruling in BRCA patents case

In a 2-1 decision, a federal appeals court today partially reversed a lower court's ruling in a case challenging patents on two human genes, BRCA1 and BRCA2, associated with hereditary breast and ovarian cancer. The court ruled that companies can obtain patents on the genes but cannot patent methods to compare those gene sequences.

3 Aug 2011

Vanderbilt researcher receives Waxman Foundation's award for B-cell lymphoma study

Scott Hiebert, Ph.D., of Vanderbilt University was awarded a $25,000 grant from the Samuel Waxman Cancer Research Foundation to further his research in abnormal BCL6 overexpression, which occurs in a common B-cell lymphoma.

3 Aug 2011

New insights into genesis and development of Sézary syndrome

Scientists at Charité - Universitätsmedizin Berlin, Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, the Max-Planck-Institut für Molekulare Genetik Berlin, and four other German institutes succeeded in proving a specific gene loss in a certain human lymphoma, the genesis of which is largely unexplained to date.

3 Aug 2011