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Celgene announces regulatory submissions for blood cancer therapies REVLIMID and ISTODAX

Celgene International Sàrl announced regulatory submissions for its blood cancer therapies REVLIMID (lenalidomide) and ISTODAX (romidepsin).

5 Jan 2011

GLUMETZA tablets are now available to wholesalers and physicians

Santarus, and Depomed, today announced that supply of GLUMETZA® 500 mg to wholesalers and retailers has resumed. GLUMETZA is a once-daily, extended release formulation of metformin and is approved for use in adults with type 2 diabetes mellitus.

5 Jan 2011

Canadian Cancer Society launches sixth annual Driven to Quit Challenge

Results of an Angus Reid Public Opinion survey conducted in December show that 20 per cent of Ontario adults are current tobacco users, including cigarettes, cigars and chew tobacco, and that half of them have tried unsuccessfully to quit in the past.

5 Jan 2011

Study identifies sailing injuries

Just as the site for the 2013 America's Cup has been announced, a study from Rhode Island Hospital highlights that the sport isn't always smooth sailing. The study was published recently in the journal Wilderness and Environmental Medicine.

5 Jan 2011

ReproCELL to enter collaborative iPS cell-derived hepatocytes R&D agreement with NIBIO

ReproCELL, Inc. (CEO: Chikafumi Yokoyama PhD) announces today that the company will enter a collaborative R&D agreement with the National Institute of Biomedical Innovation (NIBIO; Director General: Koichi Yamanishi; Osaka, Japan), which could offer new hepatocyte derived from human iPS (induced pluripotent stem) cells used for an effective in-vitro drug screening for hepatic toxicity and liver metabolism.

5 Jan 2011

P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery

Atherosclerosis is the leading cause of death in the developed world. While a number of risk factors for atherosclerosis have been defined, scientists continue to study other possible risk factors for this disease. Recent epidemiological and experimental studies link infectious agents with the development of inflammatory atherosclerosis. A hallmark of chronic infection with the oral pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response.

5 Jan 2011

Alzheimer's Association applauds President Obama for signing National Alzheimer's Project Act into law

As the leading care, research and advocacy organization for Alzheimer's disease, the Alzheimer's Association® applauds President Obama for signing the National Alzheimer's Project Act(NAPA) into law. NAPA creates for the first time a coordinated national strategy to confront one of America's most feared and costly diseases, a disease that will only plague more baby boomers as they age.

5 Jan 2011

Safe vaccine protects mice against effects of cocaine

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

5 Jan 2011

Study on aberrant cellular localization in the brain

Normally, cortical nerve cells or neurons reside in the brain's gray matter with only a few scattered neurons in the white matter, but some people with schizophrenia have a higher number of neurons in the white matter. Neuronal migration errors may arise in schizophrenia as a consequence of both genetic and environmental factors.

5 Jan 2011

ACE identifies key objectives to combat obesity epidemic in the U.S.

The American Council on Exercise, America's leading authority on fitness and the largest nonprofit fitness certification, education and training organization in the world, today announced its vision for the future of the fitness industry and overall outlook for America's focus on healthy living in 2011.

5 Jan 2011

Anaphylatoxin C5a may be responsible for devastating effects of atherosclerosis

For decades, doctors have looked at fitness levels, weight, and overall health risk factors for heart disease and stroke. Now, they may soon add a new risk factor to the list: activation of the complement system. The complement system is usually implicated in immune responses, but now there's a role for it in cardiovascular disease.

5 Jan 2011

Critical tuning dial for controlling whole body energy

Researchers have found what appears to be a critical tuning dial for controlling whole body energy, according to a new report in the January issue of Cell Metabolism, a Cell Press publication. When energy levels within cells drop, it sets off a series of events designed to increase the amount of calorie-rich dietary fat that the body will absorb.

5 Jan 2011

iHealth Lab introduces Blood Pressure Monitoring System for iPhone, iPod touch and iPad

iHealth Lab Inc., a pioneering designer and manufacturer of digital personal healthcare products, today announced the launch of the iHealth Blood Pressure Monitoring System for iPhone, iPod touch and iPad. Comprised of a hardware dock, blood pressure arm cuff and iHealth App, this breakthrough product lets users self-monitor their blood pressure from the convenience of their home, and share the results with friends, family and most importantly, their doctor.

5 Jan 2011

New mouse model with deficiency of lipoprotein lipase in neurons

Researchers at the University of Colorado School of Medicine have created a new and exciting mouse model to study how lipid sensing and metabolism in the brain relate to the regulation of energy balance and body weight. The research team, led by Hong Wang, PhD, created mice with a deficiency of lipoprotein lipase (LPL) in neurons, and observed two important reactions.

5 Jan 2011

Blocking activation of delta-PKC enzyme could protect lungs from neutrophil-mediated damage

All of us may be able to breathe a little easier now that scientists from Pennsylvania have found a new therapeutic target for controlling dangerous inflammation in the lungs. A new research report in the January 2011 issue of the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests that blocking the activation of an enzyme called delta-protein kinase C (delta-PKC) could protect the lungs from neutrophil-mediated damage, which can result in out of control inflammation.

5 Jan 2011

Polsa Pura Bracelet is an effective tool for healthy weight loss

The Polsa Pura Bracelet is a new entry into the health and weight loss market, and is proving to be the secret weapon that many dieters need to develop healthy eating habits and lose weight for good.

5 Jan 2011

Alnylam presents ALN-VSP Phase I trial results for liver cancer

Alnylam Pharmaceuticals, a leading RNAi therapeutics company, today presented new clinical data from its ALN-VSP Phase I liver cancer trial in a presentation at the Dana-Farber Cancer Institute in Boston. Results from molecular analysis of human biopsy samples showed achievement of pharmacologically relevant siRNA drug levels in tissues.

5 Jan 2011

New research finds physicians are not following standard care guidelines for OA

New research found clinicians who care for patients with osteoarthritis are likely not following standard care guidelines that are based on current medical evidence.

5 Jan 2011

Removal of ZIP proteins from hippocampus cell protects them from injury

Researchers in the Blue Bird Circle Developmental Neurogenetics Laboratory in the department of neurology at Baylor College of Medicine have discovered that zinc enters cells through specialized protein gates known as ZIP transporters, and removing these ZIP proteins from cells in the hippocampus significantly protects them from injury.

5 Jan 2011

Higher measures of walking speed associated with increased length of survival among older adults

In an analysis that included data from 9 studies, having higher measures of walking speed among older adults was associated with increased length of survival, according to a study in the January 5 issue of JAMA.

5 Jan 2011