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InteRNA, Silence partner to develop novel microRNA therapeutics for cancer

Silence Therapeutics plc, a leading global RNA interference (RNAi) therapeutics company, and InteRNA Technologies B.V., a biopharmaceutical company developing pathway targeted microRNA-based therapeutics for cancer, today announce that they have entered into an agreement to develop novel microRNA therapeutics for the treatment of cancer.

12 Sep 2011

AHRQ finds decline in hospitalizations for pica eating disorder between 2007-2009

Eating disorders as the primary reason for entering the hospital declined by 23 percent from 2007 and 2009, after a steep and steady increase from 1999 to 2007, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

12 Sep 2011

Specialists propose changes to allocation and distribution of organs for liver transplants

Transplantation specialists have proposed changes to the allocation and distribution of organs used for liver transplants. The recommended policy modifications take into account the scarcity of available organs, ensuring rapid allocation and delivery of the organ to those most in need in order to reduce mortality for waitlisted patients.

12 Sep 2011

FDA grants orphan drug designation for Avedro's VibeX to treat Keratoconus

Avedro, Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to the Company's VibeX for use with its KXL System (UVA irradiation) for Corneal Cross-linking to treat Keratoconus.

12 Sep 2011

Roche initiates Phase 1 clinical trial of investigational drug for Down syndrome

Roche today announced the initiation of its first Phase 1 clinical trial to investigate the safety and tolerability of a molecule designed to address the cognitive and behavioral deficits associated with Down syndrome.

12 Sep 2011

New treatment strategy for dominant forms of muscular dystrophy

Investigators at The Research Institute at Nationwide Children's Hospital are studying a potential new treatment strategy for dominant forms of muscular dystrophy, thanks to preliminary funding from The Ohio State University Center for Clinical and Translational Science.

12 Sep 2011

Human gliomas release excess levels of glutamate and trigger seizures

Glioma, one of the most deadly and common types of brain tumor, is often associated with seizures, but the origins of these seizures and effective treatments for them have been elusive. Now a team funded by the National Institutes of Health has found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures.

12 Sep 2011

Researchers describe new function of HCN channels in the heart

The heartbeat is the result of rhythmic contractions of the heart muscle, which are in turn regulated by electrical signals called action potentials. Action potentials result from the controlled flow of ions into heart muscle cells (depolarization) through channels in their membranes, and are followed by a compensating reverse ion current (repolarization), which restores the original state. If the duration of the repolarization phase is not just right, the risk of ventricular arrhythmia and sudden cardiac death increases significantly.

12 Sep 2011

Common genetic variant may predispose people to acute dissections

Richard Holbrooke, John Ritter, Lucille Ball, Jonathan Larson and Great Britain's King George II were all taken by the same silent killer: an acute aortic dissection. Now, scientists led by researchers at The University of Texas Health Science Center at Houston and Baylor College of Medicine have found an association with a common genetic variant in the population that predisposes people to acute dissections and can approximately double a person's chances of having the disease.

12 Sep 2011

Scientists identify 28 blood pressure-associated genetic variants

A new report from scientists at Massachusetts General Hospital (MGH) and their colleagues in centers around the world finds that common variants in 28 regions of DNA are associated with blood pressure in human patients.

12 Sep 2011

Febrile seizures in children may be linked to respiratory alkalosis

New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity.

12 Sep 2011

Researchers identify 29 DNA sequence variations linked with blood pressure

A study involving more than 200,000 people worldwide has identified 29 DNA sequence variations in locations across the human genome that influence blood pressure.

12 Sep 2011

Study: Regional differences exist in treatment of patients with acute cerebral infarction

Considerable regional differences exist in the treatment of patients with acute cerebral infarction. This is the finding presented by Erwin Stolz and his co-authors in the current issue of Deutsches Ärzteblatt International.

12 Sep 2011

Australian scientists create iron-rich 'super rice'

Scientists from three universities in South Australia and the University of Melbourne have created genetically modified rice that "has up to four times more iron than conventional rice and twice as much zinc" in an effort to "provide a solution to the iron and zinc deficiency disorders that affect billions of people throughout the world," News Corp Australian Papers/Fox News reports.

12 Sep 2011

NIH awards $13M grant to BMC for brain abnormality study in former ELGANS

Researchers and clinicians from Boston Medical Center (BMC) have been awarded a four year, more than $13 million grant from the National Institutes of Health (NIH) to study neurological and brain abnormalities in former extremely low gestational age newborns.

12 Sep 2011

Researchers discover 16 new gene regions that influence blood pressure

Findings, published today in Nature and Nature Genetics by the International Consortium for Blood Pressure Genome-Wide Association Studies represent a major advance in our understanding of the inherited influences on blood pressure and offer new potential therapeutic targets for prevention of heart disease and stroke - the biggest cause of death worldwide.

12 Sep 2011

NASA selects nine projects to investigate space radiation's effect on human explorers

NASA is funding nine proposals from eight states to investigate space radiation's effect on human explorers. The proposals from researchers in California, Colorado, Florida, Georgia, Maryland, Massachusetts, New York and Texas have a total value of approximately $12 million.

12 Sep 2011

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn's disease inhibits those seizures and may be able to slow a tumor's growth.

12 Sep 2011

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Nektar Therapeutics announced today that positive results from the company's Phase 2 clinical study of NKTR-102 in patients with metastatic breast cancer were presented at the ASCO 2011 Breast Cancer Symposium in San Francisco, California.

12 Sep 2011

Researchers demonstrate connection between circadian rhythm, platelet function and cardiovascular risk

Researchers at Brigham and Women's Hospital (BWH) have demonstrated that the circadian system, the body's internal clock, regulates human platelet function and causes a peak in platelet activation corresponding to the known morning peak in adverse cardiovascular events. These findings are published in PLoS ONE on September 8, 2011.

9 Sep 2011

Medical Condition News

InteRNA, Silence partner to develop novel microRNA therapeutics for cancer

AHRQ finds decline in hospitalizations for pica eating disorder between 2007-2009

Specialists propose changes to allocation and distribution of organs for liver transplants

FDA grants orphan drug designation for Avedro's VibeX to treat Keratoconus

Roche initiates Phase 1 clinical trial of investigational drug for Down syndrome

New treatment strategy for dominant forms of muscular dystrophy

Human gliomas release excess levels of glutamate and trigger seizures

Researchers describe new function of HCN channels in the heart

Common genetic variant may predispose people to acute dissections

Scientists identify 28 blood pressure-associated genetic variants

Febrile seizures in children may be linked to respiratory alkalosis

Researchers identify 29 DNA sequence variations linked with blood pressure

Study: Regional differences exist in treatment of patients with acute cerebral infarction

Australian scientists create iron-rich 'super rice'

NIH awards $13M grant to BMC for brain abnormality study in former ELGANS

Researchers discover 16 new gene regions that influence blood pressure

NASA selects nine projects to investigate space radiation's effect on human explorers

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

Nektar announces positive results from NKTR-102 Phase 2 study on metastatic breast cancer

Researchers demonstrate connection between circadian rhythm, platelet function and cardiovascular risk

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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