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Pain intensity and location can predict chronic low back pain

By some estimates, up to 85 percent of Americans have experienced low back pain and research reported in The Journal of Pain showed that pain intensity ratings, pain location and sensory and affective variables differ among individuals with acute and chronic low back pain. In some cases, these factors might be predictive of which acute pain patients may develop chronic pain.

29 Jul 2011

EGT transfers clinical grade lentiviral vector to MSKCC

Errant Gene Therapeutics, LLC, a pioneering boutique drug development firm specializing in Rare Diseases, announced the transfer of its clinical grade lentiviral vector, TNS 9.55.3, to Memorial Sloan Kettering Cancer Center.

29 Jul 2011

FDA approves Lannett's ANDA for Phentermine Resin Extended-Release Capsules

Lannett Company, Inc. today announced the U.S. Food and Drug Administration (FDA) approved its Abbreviated New Drug Application (ANDA) for Phentermine Resin Extended-Release Capsules, 15 mg and 30 mg, representing the fourth product approval the company has received in the last five weeks.

29 Jul 2011

Human kinome RNAi screening performed using Roche’s xCELLigence MP Instrument

RNA interference studies are a powerful technology for high-throughput screening. However, endpoint analyses only provide a snapshot of the analyzed cellular phenotype, as it is not possible to measure developmental changes over time.

29 Jul 2011

South Asians more likely to add organ-hugging fat linked with cardiovascular disease

It's not fair, but it's true. A new study by researchers at McMaster University has found that some ethnic groups are more likely to be adding dangerous fat onto their internal organs like their liver when they gain weight, while others just add it to their waistline.

29 Jul 2011

Scientists discover gene pattern that distinguishes severe from less aggressive bone cancer

A new University of Minnesota discovery may help bone cancer patients fight their disease more effectively, according to new research published in the September issue of Bone.

29 Jul 2011

Studies reveal new set of mutations linked with head and neck cancer

Powerful new technologies that zoom in on the connections between human genes and diseases have illuminated the landscape of cancer, singling out changes in tumor DNA that drive the development of certain types of malignancies such as melanoma or ovarian cancer.

29 Jul 2011

Veterinary medicine students more likely to struggle with depression

Veterinary medicine students are more likely to struggle with depression than human medicine students, undergraduate students and the general population, according to several recent collaborative studies from Kansas State University researchers.

29 Jul 2011

Positive data from BioMarin's MOR-100 Phase 1/2 extension study on Morquio syndrome

BioMarin Pharmaceutical Inc. today announced an update on the GALNS Phase 1/2 extension study (MOR-100) in which patients have continued treatment on an ongoing basis.

29 Jul 2011

Customized surfaces help reveal protein clumping process linked with Alzheimer's, diabetes

When normal proteins form protein clumps in the body, then alarm bells start ringing. Such clumps, called "amyloids," are closely associated with Alzheimer's disease and type 2 diabetes, formerly called adult-onset diabetes.

29 Jul 2011

Hospice services improve quality of care and support for dementia patients

Hospice services substantially improved the provision of care and support for nursing home patients dying of dementia and their families, according to an analysis of survey responses from hundreds of bereaved family members.

29 Jul 2011

NanoString introduces new assay for leukemia fusion gene analysis

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced the availability of a comprehensive multiplexed assay for the simple and cost-effective analysis of fusion genes linked to leukemia.

From NanoString Technologies 29 Jul 2011

WSU professor receives NIH grant for non-alcoholic fatty liver disease research

Kezhong Zhang, Ph.D., assistant professor of molecular medicine and genetics and of immunology and microbiology in the School of Medicine at Wayne State University, was awarded $1.7 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to explore how molecular elements in the body regulate the development of non-alcoholic fatty liver disease.

29 Jul 2011

Grapes help protect skin cells from sun's UV radiation

Some compounds found in grapes help to protect skin cells from the sun's ultraviolet radiation, according to a study by researchers from the University of Barcelona and the CSIC.

29 Jul 2011

'Systems biology' study of breast cancer

Using a "systems biology" approach - which focuses on understanding the complex relationships between biological systems - to look under the hood of an aggressive form of breast cancer, researchers for the first time have identified a set of proteins in the blood that change in abundance long before the cancer is clinically detectable.

29 Jul 2011

Houston-based Mattress Firm commits to support pancreatic cancer research

Mattress Firm, a leading specialty mattress retailer with more than 720 stores nationwide, is committed to supporting the fight against pancreatic cancer by raising funds for clinical trials through the Translational Genomics Research Institute (TGen) globalCure initiative.

29 Jul 2011