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EWS protein detects and corrects DNA damage in Ewing's sarcoma

Researchers from the CRG have discovered that ultraviolet light affects the function of the protein EWS, the mutation of which is responsible for Ewing's sarcoma. The results, to be published on 5th August in the journal Molecular Cell, indicate that the EWS protein has a protective effect on DNA.

5 Aug 2011

Glove with special fingertip can improve wearer's sense of touch

A little vibration can be a good thing for people who need a sensitive touch. Researchers at the Georgia Institute of Technology have developed a glove with a special fingertip designed to improve the wearer's sense of touch. Applying a small vibration to the side of the fingertip improves tactile sensitivity and motor performance, according to their research results.

5 Aug 2011

YM BioSciences reports preclinical results of CYT387 in multiple myeloma

YM BioSciences Inc., today reported preclinical results for its JAK1/JAK2 inhibitor CYT387 in multiple myeloma (MM), published in the advance online edition of Leukemia on July 26, 2011.

5 Aug 2011

FDA grants Orphan Drug Designation to Kamada's AAT product for type 1 diabetes

Kamada LTD., a bio-pharmaceutical company engaged in the development, manufacturing and marketing of specialty life-saving therapeutics, was granted an Orphan Drug Designation for its Alpha-1 Antitrypsin (AAT) product to treat type 1 diabetes.

5 Aug 2011

Shear stress-based method can identify vulnerable plaque in coronary arteries

Researchers at Emory and Georgia Tech have developed a method for predicting which areas of the coronary arteries will develop more atherosclerotic plaque over time, based on intracoronary ultrasound and blood flow measurements.

5 Aug 2011

Positive results from Antares Pharma VIBEX MTX clinical study on RA

Antares Pharma, Inc. today announced the positive results of a clinical study evaluating VIBEX MTX, a proprietary auto injector product designed to give a rapid subcutaneous injection of methotrexate (MTX) for the treatment of rheumatoid arthritis.

5 Aug 2011

Researchers identify genes that play a key role in pain perception

By working with individuals suffering from a severe disorder that causes sensory neurons to degenerate, researchers at the University of Montreal Hospital and CHU Sainte-Justine Hospital have discovered how a specific genetic mutation causes their patients' condition, which in turn has revealed more information about the mechanisms in our bodies which enable us to sense pain.

5 Aug 2011

Safe Kids USA to host Youth Sports Safety Clinics

With many young school athletes working hard this month to prepare for fall sports, Safe Kids USA is hosting Youth Sports Safety Clinics across the country to educate parents and coaches on how to keep children safe and prevent sports injuries, including heat-related illnesses. Nearly 3/4 of U.S. households have at least one child who plays organized sports.

4 Aug 2011

Dyax initiates ecallantide Phase 2 trial for ACE inhibitor-induced angioedema

Dyax Corp. announced today treatment of the first patient in a Phase 2 trial evaluating the efficacy and safety of ecallantide, a potent, selective, reversible inhibitor of plasma kallikrein, for acute treatment of angiotensin converting enzyme (ACE) inhibitor-induced angioedema.

4 Aug 2011

Palatin confirms initiation of AZD2820 Phase 1 trial in obesity

Palatin Technologies, Inc. confirmed today the commencement of a Phase 1 clinical trial of AZD2820, a subcutaneously-administered peptide melanocortin receptor partial agonist, under development as a single-agent therapy for the treatment of obesity.

4 Aug 2011

RNAi screen identifies Brd4 as a therapeutic target for acute myeloid leukemia

Scientists at Cold Spring Harbor Laboratory (CSHL) and five other institutions have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia.

4 Aug 2011

Boston Therapeutics files chewable metformin ANDA with FDA to treat diabetes

Boston Therapeutics, Inc., a public company registered with the SEC and a developer of diabetes therapeutics, today announced that it has submitted an Abbreviated New Drug Application (ANDA) for chewable metformin with the U.S. Food and Drug Administration.

4 Aug 2011

NanoString to begin clinical development program for Breast Cancer Intrinsic Subtyping Assay

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced that it is initiating the first in a series of studies to evaluate the clinical utility of the NanoString Breast Cancer Intrinsic Subtyping Assay.

From NanoString Technologies 4 Aug 2011

Positive results from hGH-CTP Phase II trial in growth hormone deficient adults

PROLOR Biotech, Inc. today reported positive results from a Phase II clinical trial of its long-acting CTP-modified version of human growth hormone (hGH-CTP) in growth hormone deficient adults.

4 Aug 2011

UH undergraduates seek solutions to many maladies like diabetes, Alzheimer's

Students from a variety of majors are devoting their summers to serious research at the University of Houston (UH), seeking eventual solutions to many serious maladies that include Alzheimer's, high blood pressure and cholesterol, diabetes, alcoholism and anxiety.

4 Aug 2011

NIH-funded study to assess biomarkers in the blood of TBI patients

Biomarkers in the bloodstream could provide physicians with a quick and accurate method of assessing the severity of traumatic brain injury (TBI) and helping deliver and monitor the results of therapies, such as progesterone treatment.

4 Aug 2011

U.S. PTO to reissue two patents for Dey Pharma's Perforomist Inhalation Solution

Dey Pharma L.P., a subsidiary of Mylan Inc., today announced that the U.S. Patent and Trademark Office intends to reissue both of the patents related to Perforomist Inhalation Solution 20 mcg/2mL vial that had been placed into reexamination by Sepracor, now known as Sunovion Pharmaceuticals.

4 Aug 2011

Loyola's lung-kidney transplant patient wins Bronze medal for bowling

Loyola University Medical Center patient Nathan Weimer, who has undergone transplants of both lungs and one kidney, has won a Bronze medal for bowling in the 2011 World Transplant Games.

4 Aug 2011

NIA, ACRO collaborate to create disease site-specific radiation oncology practice guidelines

National Imaging Associates (NIA), a subsidiary of Magellan Health Services, and the American College of Radiation Oncology (ACRO), the professional medical society established for educational and scientific purposes to advance the science and practice of radiation oncology, today announced the signing of a collaborative agreement.

4 Aug 2011

Aggressive medication leads to growth of drug-resistant pathogens

New research raises troubling concerns about the use of aggressive drug therapies to treat a wide range of diseases such as MRSA, C. difficile, malaria, and even cancer.

4 Aug 2011