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UAB researchers pinpoint protein that causes nephrotic syndrome

University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition.

13 Dec 2010

CTCs in metastatic breast cancer patients linked to cancer recurrence, poor survival rates

Metastatic breast cancer patients who had circulating tumor cells (CTCs) in their blood before or after high-dose chemotherapy (HDCT) followed by autologous stem cell transplantation had poor outcomes, according to researchers from the University of Texas MD Anderson Cancer Center.

13 Dec 2010

Study shows stereotactic radiation therapy as effective as surgery in elderly patients with early-stage lung cancer

A new study shows that a new type of targeted radiation therapy called stereotactic radiation therapy is just as good as surgery for patients aged 75 and older with early-stage lung cancer, according to research presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO), the International Association for the Study of Lung Cancer (ISLAC) and the University of Chicago.

13 Dec 2010

New York City surgeon performs first revision rhinoplasty cases with FDA approved PDS Plate

Today Dr. Steven Pearlman, prominent facial plastic and reconstructive surgeon based in New York City, will be performing one of the first revision rhinoplasty cases with the newly FDA approved PDS Plate. This revolutionary procedure will mark a giant leap in the world of cosmetic and reconstructive surgery.

13 Dec 2010

Research identifies two genetic variants that increase risk of endometriosis

Research published today identifies two genetic variants that increase the risk of developing endometriosis, a common gynaecological disease. The study provides clues to the origin of this often very painful condition, which has a significant impact on the quality of life of sufferers.

13 Dec 2010

Argos' AGS-004 shows feasibility in in vitro models to generate DC from viremic patients

Argos Therapeutics announced today that its Arcelis HIV immunotherapy, AGS-004, showed feasibility in in vitro models to generate fully functional dendritic cells (DC) from viremic patients.

13 Dec 2010

Better approaches to ovarian cancer screening could lower cancer deaths

Cancer prevention experts have long been frustrated by the lack of a meaningful way to screen women for ovarian cancer. It is a relatively rare disease that often progresses with few symptoms until it is too late for potentially curative treatments, and elevated values of the most commonly used biomarker used in screening, CA125, are also related to other disorders.

13 Dec 2010

Denosumab delays skeletal-related side effects in patients with breast cancer and bone metastases

For patients with breast cancer and bone metastases, denosumab delayed skeletal-related side effects five months longer compared to those on zoledronic acid, according to results presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

Insulin-secreting pancreatic islet cells have been generated from human spermatogonial stem cells (SSCs) directly isolated from human testicular tissue, researchers reported today at the American Association of Cell Biology 50th Annual Meeting in Philadelphia.

13 Dec 2010

HOXB7 gene raises tamoxifen resistance in women with early-stage breast cancer

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

Stem cell therapy can reduce risk of acute leukemia in affected individuals

Some adults and children with acute leukemia could benefit from certain transplants of blood stem cells, but the benefits are not equal across all cases of leukemia, according to a new review of 15 studies.

13 Dec 2010

Researchers present Phase III study of neoadjuvant therapy with trastuzumab and lapatinib for early breast cancer

Researchers presented Phase III efficacy data from the GeparQuinto study, a head-to-head comparison of neoadjuvant lapatinib and trastuzumab in combination with chemotherapy for patients with early breast cancer, at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

Cesarean-section deliveries may lead to degenerative back disease

Researchers from Michigan State University are studying whether pregnancies, specifically cesarean-section deliveries, are linked to a degenerative back disease that affects women three to nine times more often than men.

13 Dec 2010

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

Men with type 1 diabetes may be able to grow their own insulin-producing cells from their testicular tissue, say Georgetown University Medical Center (GUMC) researchers who presented their findings today at the American Society of Cell Biology 50th annual meeting in Philadelphia.

13 Dec 2010

High CTC level found to be early marker of poor outcome in metastatic breast cancer

A high level of circulating tumor cells (CTCs) - cells that have detached from a tumor and are circulating in the body through the blood - are an independent prognostic marker in metastatic breast cancer as first-line therapy.

13 Dec 2010

Genetic changes in HDAC9 gene may modulate onset of ER positive breast cancer and its recurrence

Investigators at The Cancer Institute of New Jersey have presented new research at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium. Their work highlights how a variation in a person's DNA sequence is associated with an earlier age of onset for breast cancer that is stimulated by the hormone estrogen (estrogen receptor positive).

13 Dec 2010

Depression drug appears effective in reducing pain associated with breast cancer treatment

A drug commonly used to treat depression and anxiety disorder was effective at reducing joint and muscle pain associated with a breast cancer treatment, according to a study from the University of Michigan Comprehensive Cancer Center.

12 Dec 2010

Medication for depression ended before recommended time

Swedish women's use of antidepressants is twice as high as that of Swedish men. However, among both female and male new users, one fifth fills only one prescription. "This can be an indication of choices being made to end treatment before the recommended time," says researcher Karolina Andersson Sundell at the Nordic School of Public Health.

10 Dec 2010

OPTN arranges first paired donation of living donor kidneys

Kathy Niedzwiecki of Pelham, NH, and Ken Crowder of St. Louis are experiencing renewed life and health thanks to the generosity of two living kidney donors.

10 Dec 2010

Sound masking therapy is of uncertain benefit when used alone to treat tinnitus

Tinnitus — what many think of as "ringing in the ears" — is the perception of sound without any real acoustic stimulation. Sound masking therapy, a common component of tinnitus treatment, is of uncertain benefit when used on its own, a new evidence review finds.

10 Dec 2010

Medical Condition News

UAB researchers pinpoint protein that causes nephrotic syndrome

CTCs in metastatic breast cancer patients linked to cancer recurrence, poor survival rates

Study shows stereotactic radiation therapy as effective as surgery in elderly patients with early-stage lung cancer

New York City surgeon performs first revision rhinoplasty cases with FDA approved PDS Plate

Research identifies two genetic variants that increase risk of endometriosis

Argos' AGS-004 shows feasibility in in vitro models to generate DC from viremic patients

Better approaches to ovarian cancer screening could lower cancer deaths

Denosumab delays skeletal-related side effects in patients with breast cancer and bone metastases

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

HOXB7 gene raises tamoxifen resistance in women with early-stage breast cancer

Stem cell therapy can reduce risk of acute leukemia in affected individuals

Researchers present Phase III study of neoadjuvant therapy with trastuzumab and lapatinib for early breast cancer

Cesarean-section deliveries may lead to degenerative back disease

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

High CTC level found to be early marker of poor outcome in metastatic breast cancer

Genetic changes in HDAC9 gene may modulate onset of ER positive breast cancer and its recurrence

Depression drug appears effective in reducing pain associated with breast cancer treatment

Medication for depression ended before recommended time

OPTN arranges first paired donation of living donor kidneys

Sound masking therapy is of uncertain benefit when used alone to treat tinnitus

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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