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UIC to begin STX209 clinical trial for treatment of autism spectrum disorders

An experimental drug to treat social withdrawal in children and young adults with autism is being studied in a clinical trial at the University of Illinois at Chicago's Institute for Juvenile Research.

13 Jul 2011

Bladder cancer patients missing out on treatment and followups: Study

A new study released this Monday by UCLA's Jonsson Comprehensive Cancer Center shows a large majority of patients with high-grade non-muscle invasive bladder cancer do not receive the recommended treatment and surveillance, leaving them at higher risk for bladder cancer recurrence, progression, and death.

13 Jul 2011

Enrollment commences in Exact Sciences' colorectal cancer screening trial

Exact Sciences today announced the initiation of the pivotal trial for the company's multi-marker molecular diagnostic screening test for the early detection of colorectal cancer.

13 Jul 2011

Eating nuts daily could help control type 2 diabetes and prevent complications

Eating nuts every day could help control Type 2 diabetes and prevent its complications, according to new research from St. Michael's Hospital and the University of Toronto.

13 Jul 2011

Researchers identify biomarker for familial risk of autism

Siblings of people with autism show a similar pattern of brain activity to that seen in people with autism when looking at emotional facial expressions. The University of Cambridge researchers identified the reduced activity in a part of the brain associated with empathy and argue it may be a 'biomarker' for a familial risk of autism.

13 Jul 2011

FDA clears St. Jude Medical's Epiducer lead delivery system for neurostimulation

St. Jude Medical, Inc., a global medical device company, today announced the U.S. Food and Drug Administration (FDA) clearance and limited market release of the Epiducer lead delivery system for neurostimulation therapy.

13 Jul 2011

Positive results from sarilumab Phase 2b trial on RA, ankylosing spondylitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced results from Phase 2b trials in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) with sarilumab, a novel, high-affinity, subcutaneously administered, fully-human antibody targeting the interleukin-6 receptor.

13 Jul 2011

Arena reports APD811 Phase 1 trial results against pulmonary arterial hypertension

Arena Pharmaceuticals, Inc. announced today results from a Phase 1 clinical trial of APD811, an orally bioavailable agonist of the prostacyclin receptor which is intended for the treatment of pulmonary arterial hypertension, or PAH.

13 Jul 2011

Cook Medical's Zenith Spiral-Z AAA iliac leg graft receives FDA premarket approval

Cook Medical has received premarket approval (PMA) from the U.S. Food and Drug Administration (FDA) for its Zenith Spiral-Z AAA Iliac Leg Graft. The device is indicated for use in patients with abdominal aortic aneurysms (AAA) that require graft support in the iliac artery.

13 Jul 2011

Coronary artery disease is a predictor for new-onset atrial fibrillation after heart attack

Results from a case control study show that coronary artery disease affecting the atrial branches is an independent predictor for new-onset atrial fibrillation (AF) after acute myocardial infarction (MI), or heart attack.

12 Jul 2011

EPO grants patent for Aeterna Zentaris' perifosine to treat benign, malignant tumours

Aeterna Zentaris Inc. today announced that the European Patent Office has granted a patent for the use of alkyl phosphocholines, more specifically perifosine, in the preparation of a medicament for the treatment of benign and malignant tumours, prior to and/or during the treatment with approved anti-tumour anti-metabolites such as 5FU and capecitabine.

12 Jul 2011

New animal model for studying development of testicular germ cell tumors

A team of researchers from Spain and Switzerland have developed a new model for studying the development of testicular germ cell tumors by transplanting embryonic stem cells into the seminiferous tubules in mouse models, resulting in the development of testicular germ cell tumors (TGCT) that mimic the early stages of TGCT development.

12 Jul 2011

HIV patients with mental illness can benefit from APRN care management

In a four-year study, researchers at the University of Pennsylvania have found that assigning adults with serious mental health illness who are HIV positive to the care of advanced practice nurses (APRN) to help navigate the health care system and maintain adherence to drug regimens reduced depression and improved their overall physical health, indicating that healthcare policy should be revamped to provide this support.

12 Jul 2011

New insights into how cancer cells can maintain resistance to chemotherapy

Researchers from the Royal College of Surgeons in Ireland (RCSI) have conducted a study which reveals new insights into how cancer cells can maintain a resistance to chemotherapy resulting in cancer relapse.

12 Jul 2011

Affymetrix commences shipment of gene profiling reagents

Affymetrix, Inc. today began shipping its FDA-cleared Gene Profiling Reagents. Affymetrix also announced the availability of the new Gene Profiling Array cGMP U133 P2, a version of the widely cited Human Genome U133 Plus 2.0 Array, as another component to its GeneChip Instrument System, which is used by Affymetrix partners for assay development.

12 Jul 2011

SUMO molecules might prevent protein aggregations that typify PD

A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.

12 Jul 2011

Abstainers may face higher risk of death than moderate drinkers

The author of this paper set out to determine the extent to which potential "errors" in many early epidemiologic studies led to erroneous conclusions about an inverse association between moderate drinking and coronary heart disease.

12 Jul 2011

One-fifth of all patients with fatal pulmonary disease receive delayed diagnosis

One-fifth of all patients with pulmonary arterial hypertension suffer with the fatal disease for more than two years before being correctly diagnosed and properly treated, according to a new national study led by researchers at Intermountain Medical Center in Salt Lake City.

12 Jul 2011

Osteoporosis, low bone density common in people with early-stage MS

Osteoporosis and low bone density are common in people in the early stages of multiple sclerosis (MS), according to a new study published in the July 12, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jul 2011

Researchers find clear changes in how emotions are processed in smokers

A team of researchers led by the University of Bonn found clear changes in how emotions are processed in smokers. After an abstinence period of 12 hours, the brain's fear center was mostly out of commission in addicts.

12 Jul 2011