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New 3D tissue model offers hope for scleroderma treatment

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, liver, and kidneys, as well as skin.

22 Jul 2025

Low treatment completion rates hinder recovery for teens with cannabis use disorder

Cannabis use disorder in adolescents in the United States remains a growing threat despite declines in cannabis use.

22 Jul 2025

New insights into social factors shaping mental health outcomes

Mental illnesses are thought to be caused by both biological and environmental factors in complex interaction.

22 Jul 2025

New study evaluates impact of changing race definitions on U.S. cancer data

Tracking race-specific rates of cancer incidence and mortality is important for identifying racial differences in these outcomes and for monitoring efforts aimed at achieving the highest level of health for all.

22 Jul 2025

Cleaner air after industrial plant closure improves lung health in local residents

A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA, resulted in immediate improvements in respiratory health.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Extreme childhood obesity drives liver and diabetes risks

Extreme obesity in US youth has risen significantly, linked to higher rates of diabetes and liver complications, necessitating immediate public health action.

22 Jul 2025

Date vinegar lowers blood sugar and cholesterol in type 2 diabetes

This study reveals that red date vinegar intake improves blood glucose and lipid profiles in type 2 diabetes, indicating potential for metabolic risk reduction.

22 Jul 2025

PFAS exposure may increase the risk of developing type 2 diabetes

Exposure to a class of synthetic chemicals known as per- and polyfluoroalkyl substances (PFAS)-often called "forever chemicals"-may increase the risk of developing type 2 diabetes, according to a new study led by Mount Sinai researchers.

22 Jul 2025

Weight regain observed in patients after ending obesity drug treatment

Patients prescribed drugs to help them lose weight may experience a rebound in weight gain after halting their prescription, finds a meta-analysis published in BMC Medicine.

22 Jul 2025

Gluten may not be the culprit for many people with irritable bowel syndrome

A new study from McMaster University researchers has found that many people with irritable bowel syndrome (IBS) who believe they are sensitive to gluten or wheat may not actually react to these ingredients.

22 Jul 2025

Uranium isotope in urine identified as early warning sign of kidney damage

A new study by researchers at Columbia University Mailman School of Public Health identified that uranium's isotopic composition can be used as a biomarker to noninvasively measure accumulation of uranium in the kidneys.

22 Jul 2025

New study reveals distinct form of diabetes in African youth

An international team of researchers has made a key discovery: many children and young adults in Sub-Saharan Africa diagnosed with type 1 diabetes (T1D) may have a different form of the disease - one not caused by the immune system, unlike classic T1D.

21 Jul 2025

New genetic discovery could change how Friedreich's ataxia is diagnosed

A University of Oklahoma researcher is the first to discover that the sequence of the genetic defect in the neuromuscular disease Friedreich's ataxia isn't always as uniform as previously thought, a breakthrough finding that could spark changes in how the condition is diagnosed and studied.

21 Jul 2025

Liver identified as key driver of cancer cachexia

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body.

21 Jul 2025

AI-powered ECG model outperforms doctors in detecting hidden heart disease

Researchers developed an AI-powered ECG model, EchoNext, that detects structural heart disease with high accuracy across diverse hospitals and patient populations. The model outperformed cardiologists and could identify thousands of undiagnosed cases, potentially transforming cardiac screening.

21 Jul 2025

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

Researchers discovered that people carrying the APOE ε4 gene variant share a unique immune-related protein signature across their blood, brain, and cerebrospinal fluid—regardless of neurodegenerative disease diagnosis. This signature reveals a fundamental, disease-independent vulnerability linked to APOE ε4, reframing our understanding of genetic risk in conditions like Alzheimer's, Parkinson’s, ALS, and FTD.

21 Jul 2025

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging.

21 Jul 2025

Muscle loss from GLP-1 drugs could undermine long-term health

Popular GLP-1 drugs help many people drop tremendous amounts of weight, but the drugs fail to provide a key improvement in heart and lung function essential for long-term good health, University of Virginia experts warn in a new paper.

21 Jul 2025