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New research aims to unravel genetic mysteries of polycystic kidney disease

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the United States.

14 Mar 2025

New therapeutic approach shows promise for pediatric high-grade gliomas

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options.

14 Mar 2025

Social advantage reduces risk of age-related diseases and slows aging

People with favorable socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological aging than peers of the same age, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

WEHI team makes major strides in the fight against Parkinson's disease

WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition.

14 Mar 2025

Study explores impact of severe tricuspid regurgitation in AFMR patients

Atrial functional mitral regurgitation (AFMR) is a common type of MR linked to high rates of heart failure, highlighting the need to understand its prognostic factors.

14 Mar 2025

Modified tool helps assess symptoms in cognitively impaired nursing home residents

As many as half of nursing home residents are cognitively impaired and may be unable to communicate symptoms such as pain or anxiety to the staff and clinicians caring for them.

14 Mar 2025

CityUHK leads groundbreaking project to develop new platform for early cancer detection

Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods.

13 Mar 2025

IRENE network enhances stroke care and patient outcomes in Europe

Stroke can come out of the blue, even in people who have been healthy all their lives. Unlike some other health conditions that develop gradually, a stroke occurs suddenly when blood flow to the brain is blocked in a cerebral artery, causing the brain to essentially stop functioning almost immediately. What's remarkable about stroke treatment is its extreme time sensitivity.

13 Mar 2025

Parkinson’s disease will affect 25 million people by 2050, study warns

Global Parkinson’s disease cases are projected to more than double to 25.2 million by 2050, driven largely by aging populations and socio-demographic factors. The sharpest increases are expected in Sub-Saharan Africa and South Asia, with men disproportionately affected.

13 Mar 2025

Special class of RNA molecules may provide a new target to treat gastric cancer

Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer-among the world's deadliest forms of the disease.

13 Mar 2025

Firefighting chemicals leave brain cancer-linked mutations, study shows

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting occupational risk. The study highlights a clear link between firefighting, chemical exposure, and brain cancer mutations.

13 Mar 2025

New flexible hearing aid offers non-invasive solution for conductive hearing loss

A study from researchers at Wake Forest University School of Medicine highlights a new approach in addressing conductive hearing loss. A team of scientists, led by Mohammad J. Moghimi, Ph.D., assistant professor of biomedical engineering, designed a new type of hearing aid that not only improves hearing but also offers a safe, non-invasive alternative to implantable devices and corrective surgeries.

13 Mar 2025

Struggling with weight? Eat more legumes, cut red meat, and skip soda

Diets rich in whole grains, nuts, legumes, and fruits help reduce obesity risk, while red meat and sugary drinks increase it. Researchers reviewed global evidence to identify which foods support or hinder weight management.

13 Mar 2025

Study shows how autism-linked picky eating causes serious vitamin deficiencies

Children with autism spectrum disorder (ASD) face a high risk of multiple micronutrient deficiencies, especially vitamins A, D, B12, and calcium, due to extreme food selectivity. These deficiencies can lead to severe health issues like rickets, vision loss, and immune dysfunction, even in children with normal body weight.

13 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

Targeting MARCO enhances cancer immunotherapy effectiveness

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor with collagenous structure, or MARCO.

13 Mar 2025

Already approved drug avapritinib shows promise in treating high-grade gliomas

High-grade glioma, an aggressive form of pediatric and adult brain cancer, is challenging to treat given the tumor location, incidence of recurrence and difficulty for drugs to cross the blood-brain barrier.

13 Mar 2025

Proteins identified as key players in immunotherapy resistance for colorectal cancer

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer.

13 Mar 2025

Combination immunotherapy improves treatment response for head and neck cancer

Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.

13 Mar 2025

Portable system detects mild cognitive impairment in older adults

Mild cognitive impairment (MCI) can be an early indicator of Alzheimer's disease or dementia, so identifying those with cognitive issues early could lead to interventions and better outcomes.

13 Mar 2025