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Notch-blocking drug effective against brain cancer stem cells, but more than one targeted attack needed

Working with mice, Johns Hopkins scientists who tested drugs intended to halt growth of brain cancer stem cells - a small population of cells within tumors that perpetuate cancer growth - conclude that blocking these cells may be somewhat effective, but more than one targeted drug attack may be needed to get the job done.

26 Feb 2010

Widely used biomarkers in early detection of liver cancer are not ideal: Study

Widely used biomarkers are not optimal in early detection of liver cancer, the third most common cause of cancer-related death worldwide, according to a new study published in this month's Gastroenterology.

26 Feb 2010

Larynx preservation using chemotherapy followed by radiation is effective treatment: Study

Head and neck cancer patients receiving induction chemotherapy followed by radiation to preserve their larynx have a low-risk of severe voice disability and almost half experienced no eating or swallowing problems, according to a first of its kind study presented at the Multidisciplinary Head and Neck Cancer Symposium, sponsored by AHNS, ASCO, ASTRO and SNM.

26 Feb 2010

UCLA School of Nursing selects CytoCore's PadKit Collection Kit for comparative cytology study of cervical cancer

CytoCore Inc., the developer of cost-effective products used in the practice of cytology for the detection and diagnosis of cancer and cancer related diseases, announced today that PadKit® Collection Kit, a transport kit using an intralabial device for the collection of gynecological samples, has been selected by the UCLA School of Nursing as the sample collection system for a comparative cytology study of cervical cancer.

26 Feb 2010

$Fragility fractures: 'Own the Bone' program for enhancing prevention and treatment$

Fragility fractures: 'Own the Bone' program for enhancing prevention and treatment

As many as half of all women and a quarter of men over the age of 50 can expect to sustain a fractured bone related to osteoporosis or low bone density. To enhance prevention and treatment of these fragility fractures, NewYork-Presbyterian Hospital/Columbia University Medical Center has implemented an innovative program called Own the Bone™ developed by the American Orthopaedic Association.

26 Feb 2010

Prevention of heart attacks: Resveratrol appears to exhibit broader action than aspirin

With the realization that half of the people experiencing a sudden mortal heart attack were taking aspirin on the day of their demise, and the fact that higher-than-recommended doses of aspirin are needed to prevent blood clot formation in coronary arteries, coupled with an announcement that the red wine molecule resveratrol (rez-vair-ah-trawl) may protect from sudden mortal heart attack in a superior fashion to aspirin, suggests re-evaluation of cardiology's current instruction regarding prevention of heart attacks, says Nate Lebowitz MD, cardiologist with the Advanced Cardiology Institute in Ft. Lee, New Jersey.

26 Feb 2010

Genoptix to participate in Aetna's national provider network to offer laboratory and diagnostic services

Genoptix, Inc. today announced that it will participate in Aetna's (AET) national provider network to offer specialized laboratory and comprehensive diagnostic services designed to optimize the care of patients suffering from hematomalignancies, or cancers of the blood and bone marrow, including leukemia and lymphoma.

26 Feb 2010

Integrative oncology program aims to address cancer patients' needs from every angle

The very instant Penny Kukovec was diagnosed with breast cancer her world permanently changed. Suddenly, it felt as if her life was out of her control. She felt powerless and overwhelmed. There were so many unanswered questions.

26 Feb 2010

Researchers develop new technique to reduce acrylamide in French fries

Researchers of Ghent University - department of Food Safety and food Quality developped a technique to to reduce acrylamide in French fries on an industrial scale. Acrylamide is a product that may cause cancer and was discovered in various foods.

26 Feb 2010

Evolving sex disparity in midlife stroke prevalence: Further study needed

When it comes to stroke prevalence, it appears that the gender gap is widening. According to a new report from a researcher at the Keck School of Medicine of the University of Southern California (USC), women between the ages of 35 and 64 are almost three times more likely to have a stroke compared to men in the same age group.

26 Feb 2010

Rapid, multiplexed genotyping method to identify SNPs that affect warfarin dose developed

Researchers from the Ohio State University have developed a rapid, multiplexed genotyping method to identify the single nucleotide polymorphisms (SNPs) that affect warfarin dose. The related report by Yang et al, "Rapid Genotyping of SNPs Influencing Warfarin Drug Response by SELDI-TOF Mass Spectrometry," appears in the March 2010 issue of the Journal of Molecular Diagnostics.

26 Feb 2010

Nanotechnology to tackle side effects and drug resistance in treatment of cancer

Huixin He, associate professor, nanoscale chemistry at Rutgers University, Newark, and Tamara Minko, professor at the Rutgers Ernest Mario School of Pharmacy, have developed a nanotechnology approach that potentially could eliminate the problems of side effects and drug resistance in the treatment of cancer. Under traditional chemotherapy, cancer cells, like bacteria, can develop resistance to drug therapy, leading to a relapse of the disease.

26 Feb 2010

Combining DCP and AFP biomarkers may improve early detection of liver cancer

While biomarkers are needed to complement ultrasound in the early detection of hepatocellular carcinoma (HCC; liver cancer), neither des-gamma-carboxy prothrombin (DCP) nor the most widely used biomarker, alpha fetoprotein (AFP), is optimal, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

26 Feb 2010

Paralysis from a stroke: Rare nerve transfer improves mobility

The Plastic Surgery Center today announced the successful results of a rare nerve transfer performed for the first known time on a stroke patient to reverse paralysis. Following the procedure, which was led by Dr. Andrew Elkwood, M.D., 47-year old Vincent Filipini is now able to lift, move and bend his once paralyzed arm. Mr. Filipini continues to show improvement in his mobility.

26 Feb 2010

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

Advanced cancer patients who regularly received massages averaging 14 minutes or more by a partner or family member declined in stress scores over four weeks, according to results of a study reported at the 7th annual conference of the American Psychosocial Oncology Society.

26 Feb 2010

Genetic factors influence likelihood of developing PTSD

The 1994 genocide in Rwanda resulted in the mass killing of up to one million people over the course of about 100 days. Although the exact death toll is unknown, experts estimate that as much as 20% of the country's entire population was murdered. There can be no doubt or surprise then that some of the survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder that can develop after witnessing or experiencing a traumatizing event, such as abuse, war, or natural disaster.

26 Feb 2010

Intracranial stenting, intra-arterial tPA more effective than other urgent ischemic stroke treatments

Techniques that keep brain arteries open (intracranial stenting) or inject clot-busting drugs directly to the brain (intra-arterial tPA) may be more effective than other urgent ischemic stroke treatments, researchers said at the American Stroke Association's International Stroke Conference 2010.

26 Feb 2010

Over 600 programs for Aboriginal Canadians with diabetes at risk of being shut, renewed federal funding needed

The federal government must renew funding for the Aboriginal Diabetes Initiative (ADI) in next week's budget or more than 600 programs for Aboriginal Canadians living with diabetes are at risk of being shut down, according to the Canadian Diabetes Association and the National Aboriginal Diabetes Association (NADA).

26 Feb 2010

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

Complementary approaches to Alzheimer's research were recognized as four scientists received the prestigious MetLife Foundation Awards for Medical Research in Alzheimer's Disease in Washington, D.C.

26 Feb 2010

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in two papers published back-to-back online at the Proceedings of the National Academies of Science.

26 Feb 2010

Medical Condition News

Notch-blocking drug effective against brain cancer stem cells, but more than one targeted attack needed

Widely used biomarkers in early detection of liver cancer are not ideal: Study

Larynx preservation using chemotherapy followed by radiation is effective treatment: Study

UCLA School of Nursing selects CytoCore's PadKit Collection Kit for comparative cytology study of cervical cancer

Fragility fractures: 'Own the Bone' program for enhancing prevention and treatment

Prevention of heart attacks: Resveratrol appears to exhibit broader action than aspirin

Genoptix to participate in Aetna's national provider network to offer laboratory and diagnostic services

Integrative oncology program aims to address cancer patients' needs from every angle

Researchers develop new technique to reduce acrylamide in French fries

Evolving sex disparity in midlife stroke prevalence: Further study needed

Rapid, multiplexed genotyping method to identify SNPs that affect warfarin dose developed

Nanotechnology to tackle side effects and drug resistance in treatment of cancer

Combining DCP and AFP biomarkers may improve early detection of liver cancer

Paralysis from a stroke: Rare nerve transfer improves mobility

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

Genetic factors influence likelihood of developing PTSD

Intracranial stenting, intra-arterial tPA more effective than other urgent ischemic stroke treatments

Over 600 programs for Aboriginal Canadians with diabetes at risk of being shut, renewed federal funding needed

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

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