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Music benefits patients on mechanical ventilation

The benefits of listening to music for patients on mechanical ventilation was revealed in a systematic review by a team of Cochrane researchers led by Drexel University College of Nursing and Health Professions associate professor Dr. Joke Bradt. The review found that listening to music may relax patients and potentially result in fewer complications.

4 Dec 2010

Pfizer plans regulatory submissions of bosutinib for CML based on BELA study

Pfizer Inc. announced today it is planning regulatory submissions of bosutinib in patients with chronic myeloid leukemia (CML) based on data from a clinical program evaluating the compound in newly diagnosed and previously treated patients. These regulatory submissions are planned for 2011.

4 Dec 2010

Chaperone protein study could lead to effective therapies for Alzheimer's, neurological disorders

Dynamic regulation of the chaperone protein Hsp27 was required to get rid of abnormally accumulating tau in the brains of mice genetically modified to develop the memory-choking tau tangles associated with Alzheimer's disease, a University of South Florida-led study found.

4 Dec 2010

Neurostimulation effective for management of chronic pain

St. Jude Medical, Inc., a global medical device company, today announced two-year results in a post-market clinical study evaluating neurostimulation (spinal cord stimulation) for the management of chronic low back pain. Presented at the 14th annual North American Neuromodulation Society (NANS) meeting in Las Vegas, the study found that 70 percent of neurostimulation patients reported overall pain relief of 50 percent or better at their final two-year visit.

4 Dec 2010

New web-based CME program to improve cancer care in rural areas

Nearly a quarter of Americans live in rural areas, which consistently report higher cancer mortality rates than urban and suburban areas. Among the complex causes for this disparity is that only 10 percent of physicians practice in rural areas and almost 4 out of 10 rural residents live at least an hour from an urban area. Finding the time, transportation, and financial resources for travel to urban academic medical centers, the standard bearers for quality cancer care, often proves difficult.

4 Dec 2010

Onconova announces three presentations on Estybon- (ON 01910.Na) at ASH 2010

Onconova Therapeutics announces its late-stage anticancer agent, Estybon- (ON 01910.Na), will be featured in three presentations at the 52nd American Society of Hematology (ASH) Annual Meeting in Orlando, FL, December 4-7, 2010.

4 Dec 2010

Researchers decipher mechanism responsible for dental plaque sticking to teeth

The Groningen professors Bauke Dijkstra and Lubbert Dijkhuizen have deciphered the structure and functional mechanism of the glucansucrase enzyme that is responsible for dental plaque sticking to teeth. This knowledge will stimulate the identification of substances that inhibit the enzyme. Just add that substance to toothpaste, or even sweets, and caries will be a thing of the past. The results of the research have been published this week in the journal Proceedings of the National Academy of Sciences (PNAS).

4 Dec 2010

Merck to present multiple clinical studies of dinaciclib at ASH Annual Meeting

Ligand Pharmaceuticals Incorporated today announced that multiple clinical studies of dinaciclib (SCH 727965) will be presented by Merck at the upcoming 52nd American Society of Hematology Annual Meeting being held in Orlando, Florida at the Orange County Convention Center, December 4-7, 2010.

4 Dec 2010

FDA Advisory Committee votes in favor of expanded use of LAP-BAND gastric band

Allergan, Inc. (NYSE: AGN) today announced the U.S. Food and Drug Administration (FDA) Gastroenterology and Urology Devices Panel of the Medical Devices Advisory Committee has recommended with an 8-2 vote that the FDA extend the currently approved use of the LAP-BAND® System, Allergan's gastric band, on the basis of a favorable benefit-risk profile for weight reduction in obese adults who have failed more conservative weight reduction alternatives and have a Body Mass Index (BMI) of at least 35 or a BMI ≥30 and at least one comorbid condition.

4 Dec 2010

MDS Foundation: Significant advances made in understanding, treating MDS, AML

The Myelodysplastic Syndromes Foundation today said significant advances are being made in understanding and treating MDS and a related condition, AML (acute myeloid leukemia). Key studies being presented this week include data on new markers and genetic mutations to predict susceptibility to MDS and response to treatment.

4 Dec 2010

Information technology could improve prevention, treatment of depression

Could information technology and data mining techniques be used to improve the diagnosis and treatment of depression? That's the question scientists in Australia hope to have answered in a forthcoming issue of the International Journal of Functional Informatics and Personalised Medicine.

4 Dec 2010

Active recreational athletes at risk for shoulder injuries this holiday season, say doctors

Around the holidays, even the friendliest game of flag football can lead to injury. According to sports medicine doctors at Hospital for Special Surgery, older and newly active recreational athletes are particularly at risk for shoulder injuries.

4 Dec 2010

EHSI announces acquisition of Rotary Cell Culture System

Emerging Healthcare Solutions, Inc. announced today that it has acquired a Rotary Cell Culture System, or bioreactor, developed using revolutionary NASA research in the field of microgravity.

4 Dec 2010

Mitoxantrone increases survival for children with relapsed ALL, trial results show

A new treatment increases survival to almost 70 per cent for children whose acute lymphoblastic leukaemia returns, according to the results of a trial published online in the Lancet today (Saturday).

4 Dec 2010

Zometa improves OS, PFS in newly diagnosed multiple myeloma patients: Phase III study

A newly published study in the Lancet suggested that a first-line treatment regimen including Zometa (zoledronic acid) significantly improved overall survival and progression-free survival in newly diagnosed multiple myeloma patients compared with a regimen that included oral clodronate. The impact on survival was independent of the effect of Zometa on bone complications (also known as skeletal-related events or SREs).

4 Dec 2010

BRI enters 3-year partnership with Roche to develop human immunology programs

Baylor Research Institute (BRI), the research arm of Baylor Health Care System, announced that it has formed a three-year partnership with Roche to jointly develop programs emerging from the human immunology platforms developed at the Baylor Institute for Immunology Research (BIIR), a component of BRI.

4 Dec 2010

Gene mutation can lead to different mental illnesses when influenced by same environmental factor

Male mice born with a genetic mutation that's believed to make humans more susceptible to schizophrenia develop behaviors that mimic other major psychiatric illnesses when their mothers are exposed to an assault to the immune system while pregnant, according to new Johns Hopkins research.

4 Dec 2010

Research findings could provide breakthrough for development of effective therapies for NSCLC

Research at Virginia Commonwealth University Massey Cancer Center led by Charles E. Chalfant, Ph.D., associate professor of biochemistry and molecular Biology, discovered a previously unknown mechanism in non-small cell lung cancer cells that contributes to their ability to maintain and grow tumors. Narrowing in on this mechanism could provide a breakthrough for the development of effective therapies for NSCLC and other cancers.

4 Dec 2010

Key findings on plasma cell disorders to be presented at American Society of Hematology Annual Meeting

Caris Life Sciences, Inc., a leading biosciences company focused on enabling precise and personalized healthcare through the highest quality anatomic pathology, molecular profiling, and blood-based diagnostic services, announced that Dr. Raul Braylan, Hematopathologist and Clinical Medical Director of Hematopathology Services, will present key findings related to plasma cell disorders at the upcoming 52nd Annual Meeting and Exposition of the American Society of Hematology.

4 Dec 2010

Phase III studies should make meaningful difference in patients' quality of life: Commentary

Randomized phase III studies should be designed to find out whether a new drug or treatment makes a meaningful difference in patients' survival or quality of life, according to a commentary published online December 3rd in The Journal of the National Cancer Institute.

4 Dec 2010

Medical Condition News

Music benefits patients on mechanical ventilation

Pfizer plans regulatory submissions of bosutinib for CML based on BELA study

Chaperone protein study could lead to effective therapies for Alzheimer's, neurological disorders

Neurostimulation effective for management of chronic pain

New web-based CME program to improve cancer care in rural areas

Onconova announces three presentations on Estybon- (ON 01910.Na) at ASH 2010

Researchers decipher mechanism responsible for dental plaque sticking to teeth

Merck to present multiple clinical studies of dinaciclib at ASH Annual Meeting

FDA Advisory Committee votes in favor of expanded use of LAP-BAND gastric band

MDS Foundation: Significant advances made in understanding, treating MDS, AML

Information technology could improve prevention, treatment of depression

Active recreational athletes at risk for shoulder injuries this holiday season, say doctors

EHSI announces acquisition of Rotary Cell Culture System

Mitoxantrone increases survival for children with relapsed ALL, trial results show

Zometa improves OS, PFS in newly diagnosed multiple myeloma patients: Phase III study

BRI enters 3-year partnership with Roche to develop human immunology programs

Gene mutation can lead to different mental illnesses when influenced by same environmental factor

Research findings could provide breakthrough for development of effective therapies for NSCLC

Key findings on plasma cell disorders to be presented at American Society of Hematology Annual Meeting

Phase III studies should make meaningful difference in patients' quality of life: Commentary

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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