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Rapid, multiplexed genotyping method to identify SNPs that affect warfarin dose developed

Researchers from the Ohio State University have developed a rapid, multiplexed genotyping method to identify the single nucleotide polymorphisms (SNPs) that affect warfarin dose. The related report by Yang et al, "Rapid Genotyping of SNPs Influencing Warfarin Drug Response by SELDI-TOF Mass Spectrometry," appears in the March 2010 issue of the Journal of Molecular Diagnostics.

26 Feb 2010

Nanotechnology to tackle side effects and drug resistance in treatment of cancer

Huixin He, associate professor, nanoscale chemistry at Rutgers University, Newark, and Tamara Minko, professor at the Rutgers Ernest Mario School of Pharmacy, have developed a nanotechnology approach that potentially could eliminate the problems of side effects and drug resistance in the treatment of cancer. Under traditional chemotherapy, cancer cells, like bacteria, can develop resistance to drug therapy, leading to a relapse of the disease.

26 Feb 2010

Combining DCP and AFP biomarkers may improve early detection of liver cancer

While biomarkers are needed to complement ultrasound in the early detection of hepatocellular carcinoma (HCC; liver cancer), neither des-gamma-carboxy prothrombin (DCP) nor the most widely used biomarker, alpha fetoprotein (AFP), is optimal, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

26 Feb 2010

Paralysis from a stroke: Rare nerve transfer improves mobility

The Plastic Surgery Center today announced the successful results of a rare nerve transfer performed for the first known time on a stroke patient to reverse paralysis. Following the procedure, which was led by Dr. Andrew Elkwood, M.D., 47-year old Vincent Filipini is now able to lift, move and bend his once paralyzed arm. Mr. Filipini continues to show improvement in his mobility.

26 Feb 2010

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

Advanced cancer patients who regularly received massages averaging 14 minutes or more by a partner or family member declined in stress scores over four weeks, according to results of a study reported at the 7th annual conference of the American Psychosocial Oncology Society.

26 Feb 2010

Genetic factors influence likelihood of developing PTSD

The 1994 genocide in Rwanda resulted in the mass killing of up to one million people over the course of about 100 days. Although the exact death toll is unknown, experts estimate that as much as 20% of the country's entire population was murdered. There can be no doubt or surprise then that some of the survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder that can develop after witnessing or experiencing a traumatizing event, such as abuse, war, or natural disaster.

26 Feb 2010

Intracranial stenting, intra-arterial tPA more effective than other urgent ischemic stroke treatments

Techniques that keep brain arteries open (intracranial stenting) or inject clot-busting drugs directly to the brain (intra-arterial tPA) may be more effective than other urgent ischemic stroke treatments, researchers said at the American Stroke Association's International Stroke Conference 2010.

26 Feb 2010

Over 600 programs for Aboriginal Canadians with diabetes at risk of being shut, renewed federal funding needed

The federal government must renew funding for the Aboriginal Diabetes Initiative (ADI) in next week's budget or more than 600 programs for Aboriginal Canadians living with diabetes are at risk of being shut down, according to the Canadian Diabetes Association and the National Aboriginal Diabetes Association (NADA).

26 Feb 2010

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

Complementary approaches to Alzheimer's research were recognized as four scientists received the prestigious MetLife Foundation Awards for Medical Research in Alzheimer's Disease in Washington, D.C.

26 Feb 2010

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in two papers published back-to-back online at the Proceedings of the National Academies of Science.

26 Feb 2010

SNI clinical study using ultrasound for treatment of ICH and IVH presented at International Stroke Conference

EKOS Corporation announced today that Dr. David W. Newell, Co–Executive Director, Swedish Neuroscience Institute (Seattle, WA) presented a SNI clinical study known as ‘SLEUTH’ (Safety of Lysis with Ultrasound in the Treatment of Intracerebral (ICH) and Intraventricular Hemorrhage (IVH) at the American Heart Association International Stroke Conference (San Antonio, TX).

26 Feb 2010

Teva Pharmaceutical announces clinical study results of Copaxone in RRMS patients

Teva Pharmaceutical Industries Ltd. today announced the publication of data from the 15-year clinical study with Copaxone® (glatiramer acetate injection), which is the longest prospective and continuous evaluation ever conducted in relapsing-remitting multiple sclerosis (RRMS) patients. The data were published in the February issue of the journal Multiple Sclerosis.

26 Feb 2010

Locally advanced sinonasal malignancies: Proton beam radiation therapy promising

Proton beam radiation therapy shows encouraging results for patients with locally advanced sinonasal malignancies, according to a study presented at the Multidisciplinary Head and Neck Cancer Symposium, sponsored by AHNS, ASCO, ASTRO and SNM.

26 Feb 2010

Schizophrenia: Insight into late development of symptoms

In reports of two new studies, researchers led by Johns Hopkins say they have identified the mechanisms rooted in two anatomical brain abnormalities that may explain the onset of schizophrenia and the reason symptoms don't develop until young adulthood. Both types of anatomical glitches are influenced by a gene known as DISC1, whose mutant form was first identified in a Scottish family with a strong history of schizophrenia and related mental disorders. The findings could lead to new ways to treat, prevent or modify the disorder or its symptoms.

26 Feb 2010

Heel pain continues to be the most common reason patients seek care, say foot and ankle surgeons

If you are suffering from heel pain, you're not alone. According to foot and ankle surgeons attending the 68th Annual Scientific Conference of the American College of Foot and Ankle Surgeons in Las Vegas this week, heel pain continues to be the most common reason patients seek care. Surgeons advise the best defense to keeping pain in control is early treatment.

26 Feb 2010

Surgeons perform nation's first incision-free myotomy procedure to treat achalasia

Surgeons at UC San Diego Medical Center have performed the nation's first incision-free myotomy, a procedure to treat achalasia, a distressing disorder which causes difficulty swallowing, regurgitation and chest pain. The innovative surgery, performed through the mouth, is the most recent in a series of groundbreaking clinical trial surgeries being evaluated by the UCSD Center for the Future of Surgery.

26 Feb 2010

CPF to partner with ATS to fund Pulmonary Fibrosis research

The Coalition for Pulmonary Fibrosis and the American Thoracic Society, the world's leading professional organization for pulmonary, critical care and sleep physicians, today announced that the CPF will again partner with the ATS to fund Pulmonary Fibrosis (PF) research.

26 Feb 2010

NORD lauds FDA's establishment of new position within CDER

Peter L. Saltonstall, president and CEO of the National Organization for Rare Disorders (NORD), today said the Food and Drug Administration's (FDA) announcement that it has created a new position—Associate Director for Rare Diseases—in the agency's Center for Drug Evaluation and Research's (CDER) Office of New Drugs (OND) represents an important advance for patients with rare diseases.

26 Feb 2010

New dietary supplement blocks triggering mechanism causing breast cell mutations

Every 13 minutes a woman loses her battle with breast cancer and in 2009 alone more than 27,000 men died from prostate cancer. These powerful statistics continue to fuel research and new developments. With tens of millions of dollars in financial support from the National Cancer Institute and the U.S. Department of Defense, scientists have identified when estrogen metabolism is out of balance it can start the process leading to breast cell mutations.

26 Feb 2010

Exergames improve mood and mental health-related quality of life in seniors with SSD

Research at the Sam and Rose Stein Institute for Research on Aging at the University of California, San Diego School of Medicine suggests a novel route to improving the symptoms of subsyndromal depression (SSD) in seniors through the regular use of "exergames" - entertaining video games that combine game play with exercise. In a pilot study, the researchers found that use of exergames significantly improved mood and mental health-related quality of life in older adults with SSD.

26 Feb 2010

Medical Condition News

Rapid, multiplexed genotyping method to identify SNPs that affect warfarin dose developed

Nanotechnology to tackle side effects and drug resistance in treatment of cancer

Combining DCP and AFP biomarkers may improve early detection of liver cancer

Paralysis from a stroke: Rare nerve transfer improves mobility

Massaging advanced cancer patients for 14 minutes can reduce stress: Study

Genetic factors influence likelihood of developing PTSD

Intracranial stenting, intra-arterial tPA more effective than other urgent ischemic stroke treatments

Over 600 programs for Aboriginal Canadians with diabetes at risk of being shut, renewed federal funding needed

MetLife Foundation Awards for Medical Research in Alzheimer's Disease: Four scientists honored

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

SNI clinical study using ultrasound for treatment of ICH and IVH presented at International Stroke Conference

Teva Pharmaceutical announces clinical study results of Copaxone in RRMS patients

Locally advanced sinonasal malignancies: Proton beam radiation therapy promising

Schizophrenia: Insight into late development of symptoms

Heel pain continues to be the most common reason patients seek care, say foot and ankle surgeons

Surgeons perform nation's first incision-free myotomy procedure to treat achalasia

CPF to partner with ATS to fund Pulmonary Fibrosis research

NORD lauds FDA's establishment of new position within CDER

New dietary supplement blocks triggering mechanism causing breast cell mutations

Exergames improve mood and mental health-related quality of life in seniors with SSD

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