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Blocking release of VEGFs may inhibit tumor growth

Researchers at the University of Helsinki, Finland, and the Paul Scherrer Institute (PSI) in Villigen, Switzerland, have determined the crystal structure of the ligand binding domain of a vascular endothelial growth factor (VEGF) receptor in complex with one of its ligands (VEGF-C).

19 Jan 2010

Smoking diabetics more likely to have a heart attack

The Canadian Diabetes Association encourages all Canadians living with diabetes who smoke to take action to quit smoking in the next seven days, during National Non-Smoking Week.

19 Jan 2010

Calsed earns proprietary clinical gold standard status from Decision Resources

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Celgene/Nippon Kayaku's Calsed earns Decision Resources' proprietary clinical gold standard status in 2013 for the treatment of extensive-disease small-cell lung cancer, following its approval for the indication in 2012.

19 Jan 2010

New study indicates appendicitis may be caused by viral infection

The researchers evaluated data over a 36-year period from the National Hospital Discharge Survey and concluded in a paper appearing in the January issue of Archives of Surgery that appendicitis may be caused by undetermined viral infection or infections, said Dr. Edward Livingston, chief of GI/endocrine surgery at UT Southwestern and senior author of the report.

19 Jan 2010

Adverse childhood experiences are associated with increased risk of lung cancer

Adverse events in childhood have been linked to an increase in the likelihood of developing lung cancer in later life. Researchers writing in the open access journal BMC Public Health describe how the link is partly explained by raised rates of cigarette smoking in victims of childhood trauma, but note that other factors may also be to blame.

19 Jan 2010

Unique partnership leverages funds and technology to track and improve breast screening program

The Canadian Breast Cancer Foundation - Atlantic announced today a first-of-its-kind partnership between the breast screening programs of Nova Scotia and Newfoundland and Labrador that yield benefits that could extend to the rest of Canada and beyond.

19 Jan 2010

People with "mental lapses" more likely to have Alzheimer's disease

Older people who have "mental lapses," or times when their thinking seems disorganized or illogical or when they stare into space, may be more likely to have Alzheimer's disease than people who do not have these lapses, according to a study published in the January 19, 2010, print issue of Neurology-, the medical journal of the American Academy of Neurology.

19 Jan 2010

Psoriasis therapy costs outpace inflation

Findings from a cost model suggest that expenses for systemic psoriasis therapy appear to be increasing at a faster rate than inflation, and newer biologically derived treatments are more expensive than traditional systemic therapies, according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

19 Jan 2010

Sodium oxybate to garner over 15% of the fibromyalgia drug market despite safety concerns

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, despite potential safety concerns, Jazz Pharmaceuticals/UCB's sodium oxybate (JZP-6) will account for more than 15 percent of the fibromyalgia drug market in 2018 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan. Sodium oxybate has demonstrated robust efficacy in Phase III clinical trials for fibromyalgia and interviewed thought leaders are impressed with its effect on several key symptom domains of fibromyalgia, which include pain, sleep and fatigue.

18 Jan 2010

Boehringer Ingelheim, Priaxon announce collaboration in development of mdm2/p53 inhibitors for cancer

Boehringer Ingelheim and Priaxon entered into a worldwide collaboration to research and develop mdm2/p53 inhibitors for the treatment of cancer. Priaxon is providing its innovative and proprietary small molecule drug discovery expertise which is particularly suited to investigate inhibition of protein-protein interactions. p53 is a human tumor suppressor protein.

18 Jan 2010

Japanese MHLW approves St. Jude Medical's Genesis spinal cord stimulation system

St. Jude Medical, Inc. today announced regulatory approval from the Japanese Ministry of Health, Labor and Welfare (MHLW) for the Genesis™ spinal cord stimulation system for the management of chronic pain.

18 Jan 2010

Sunlight and vitamin D deficiency linked to 17 varieties of cancer

For humans, sunlight and vitamin D is critically important for the development, growth, and maintenance of a healthy body, from birth until death. "Humans make thousands of units of vitamin D within minutes of whole body exposure to sunlight. From what we know of nature, it is unlikely such a system evolved by chance," states Dr. John Cannell, Executive Director, Vitamin D Council.

18 Jan 2010

Plastic surgery to complete weight-loss treatment

Reconfigured body after reconfigured body, the hands of Alexander Moya, M.D., Director of the Center for Weight Loss Body Contouring and Assistant Director of the Geisinger Center for Aesthetics and Cosmetic Surgery at Geisinger Medical Center (GMC), skillfully addresses the excess skin his patients contend with following the loss of dozens, if not often hundreds, of pounds. According to Dr. Moya, it's this final therapeutic step of removing this skin and reshaping their bodies that often puts weight-loss patients at peace with themselves and what they see in the mirror every morning.

18 Jan 2010

Leslie Phillips asks Facebook users to vote for NAA in the Chase Community Giving challenge

Texas mom Leslie Phillips joins parents, grandparents, and caregivers around the country in asking Facebook users to vote for the National Autism Association (NAA) in the Chase Community Giving challenge.

18 Jan 2010

Auditory feedback pathway in the brain linked to learned vocal control identified

Scientists at Duke University Medical Center have identified neurons in the songbird brain that convey the auditory feedback needed to learn a song.

18 Jan 2010

New study examines amputation-specific pain severity in men and women

With increasing numbers of men and women serving in combat and risking traumatic injury and limb loss, a new study published in The Journal of Pain, the peer-reviewed publication of the American Pain Society, concludes that self-reported amputation-specific pain severity is similar in men and women but there are considerable gender variations in overall pain outcomes, such as emotional health and pain-coping responses.

18 Jan 2010

Research may pave for further studies on various human skin disorders

The leopard cannot change its spots, nor can the tiger change its stripes, but a new research report published in the January 2009 issue of the journal GENETICS tells us something about how cats end up with their spots and stripes

18 Jan 2010

NIH awards IU School of Optometry $2.35M for glaucoma research

An Indiana University School of Optometry researcher's ongoing work to improve testing for and treatment of one of the world's leading causes of blindness will advance with support from a $2.35 million grant from the National Institutes of Health.

18 Jan 2010

Need for further studies on clinical characteristics of Intrahepatic Cholangiocarcinoma

Incidence of intrahepatic cholangiocarcinoma (ICC) is increasing worldwide and its prognosis is very poor. Thus, further studies on its clinical characteristics for early detection and on surgical treatment for better prognosis are urgently needed.

18 Jan 2010

Research article examining the use of acupuncture to prevent PPOI published

A research article to be published on January 7 , 2010 in the World Journal of Gastroenterology addresses this question. In this prospective randomized clinical trial, the authors examined if acupuncture could prevent prolonged postoperative ileus (PPOI) after intraperitoneal surgery among patients with colon cancer in Shanghai, China.

18 Jan 2010