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Restoring brain pathways to fight opioid addiction

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model.

20 Feb 2024

Overcoming barriers to eating disorder treatment for low-income patients

Individuals with eating disorders who have low income are frequently misdiagnosed and lack adequate access to appropriate therapy, according to researchers from Weill Cornell Medicine and Columbia University Vagelos College of Physicians and Surgeons.

20 Feb 2024

Scientists identify new therapeutic approach for combating neurodegenerative diseases

A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases, offering hope of improved treatments for Alzheimer's disease, Parkinson's disease, Vanishing White Matter disease and multiple sclerosis, among others.

20 Feb 2024

Physical activity counters social isolation's mental toll

Physical activity significantly offsets the negative impact of social isolation on mental health, with neuroimaging showing its potential as a compensatory mechanism for emotional well-being.

20 Feb 2024

Healthy plant-based diets linked to lower risk of obstructive sleep apnea

People who eat a healthy, plant-based diet that is high in vegetables, fruit, whole grains and nuts are less likely to suffer with obstructive sleep apnea (OSA), according to a study published today (Wednesday) in ERJ Open Research.

20 Feb 2024

Red light therapy lowers blood sugar and mitigates glucose spikes

The researchers found that 670 nanometers (nm) of red light stimulated energy production within mitochondria, the tiny powerhouses within cells, leading to increased consumption of glucose. In particular, it led to a 27.7% reduction in blood glucose levels following glucose intake, and it reduced maximum glucose spiking by 7.5%.

20 Feb 2024

Ultra-processed foods linked to higher risk of sarcopenia

Study finds a direct correlation between ultra-processed food consumption and increased risk of low muscle mass in adults, suggesting dietary changes could combat sarcopenia.

20 Feb 2024

Early childhood food responsiveness may predict eating disorder symptoms

An enthusiastic response to food in early childhood may be linked to a higher likelihood of experiencing eating disorder symptoms in adolescence, according to a new study led by researchers at UCL and Erasmus University Rotterdam.

20 Feb 2024

Adopting key healthy behaviors reduces risk of irritable bowel syndrome

Adopting a healthy lifestyle is strongly linked to a lower risk of irritable bowel syndrome or IBS for short, finds research published online in the journal Gut.

20 Feb 2024

Functional brain changes linked to depression exposure

Study reveals that exposure to depression correlates with significant functional brain changes, varying by depression definition, without notable structural differences, emphasizing the need for precise diagnostic criteria to enhance treatment outcomes.

20 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

Historic DNA analysis identifies Down and Edwards syndromes in ancient humans

By analyzing ancient DNA, an international team of researchers have uncovered cases of chromosomal disorders, including what could be the first case of Edwards syndrome ever identified from prehistoric remains.

20 Feb 2024

Aging alters fibroblasts to promote pancreatic cancer growth

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

20 Feb 2024

Study evaluates colorectal cancer screening programs in Latin America

Little is known about colorectal cancer screening strategies throughout the Western Hemisphere, with the exception of the U.S. and Canada.

20 Feb 2024

Study reveals low utilization of PCSK9 inhibitors in high-risk patients

A new study published in Circulation: Cardiovascular Quality and Outcomes from the Family Heart Foundation - a patient-centered research and advocacy nonprofit organization dedicated to improving the lives of families impacted by inherited lipid disorders and LDL-cholesterol - revealed that utilization of proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) to reduce low-density lipoprotein cholesterol (LDL-C) remains low among high-risk patients.

20 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Ultrahigh-spatial-resolution PCD-CT improves assessment of coronary artery disease

Ultrahigh-spatial-resolution photon-counting detector CT improved assessment of coronary artery disease (CAD), allowing for reclassification to a lower disease category in 54% of patients, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

20 Feb 2024

Investigating dosage in hyperbaric oxygen therapy for post-covid conditions

Hyperbaric oxygen therapy, giving patients 100 percent oxygen at a pressure corresponding to 10-20 meters below sea level, has been around for almost 100 years.

20 Feb 2024

Novel therapy harnesses stem cell-derived exosomes for diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

20 Feb 2024

Study reveals racial disparities in access to buprenorphine for opioid use disorder

Buprenorphine, a life-saving medication for opioid use disorder, is far less accessible in geographic areas of the United States with racially and ethnically diverse populations than in predominantly white areas, according to a new study of pre-pandemic data led by health policy scientists at the University of Pittsburgh School of Public Health published today in Journal of Addiction Medicine.

20 Feb 2024