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New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

MedUni Vienna scientists discover new pain medication with fewer side effects

People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects.

6 Dec 2023

Couples often share high blood pressure, study finds

If one spouse or partner in a heterosexual couple has high blood pressure, the other partner often does too, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

6 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers - only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Twice daily electrical stimulation boosts brain plasticity and improves memory in Alzheimer's patients

Twice daily non-invasive electrical stimulation of the brain may boost mental processes (cognitive function) in people with Alzheimer's disease, suggest the results of a small clinical trial published online in the open access journal General Psychiatry.

6 Dec 2023

Music could hold the key to developing effective mental health interventions

How human beings respond to music and the biological underpinnings of this response.

6 Dec 2023

Orbitofrontal cortex holds clues for understanding and preventing depression

New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood.

6 Dec 2023

Housing instability heightens Alzheimer's risk in veterans

In a recent study published in Journal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receive a diagnosis of Alzheimer's disease or a related dementia (ADRD) than those with stable housing.

6 Dec 2023

Risk factors for the development of freezing of gait in Parkinson’s disease patients

The risk factors that influence the development of freezing of gait or FOG.

6 Dec 2023

Anti-obesity medications may offer survival benefits for osteoarthritis patients

New research published in Arthritis & Rheumatology suggests that for people overweight or with obesity who also have knee or hip osteoarthritis, a slow-to-moderate - but not fast - rate of weight loss caused by anti-obesity medications may lower their risk of premature death.

6 Dec 2023

Brain stimulation offers promise for prospective memory deficits in schizophrenia

Most people with schizophrenia have extensive impairment of memory, including prospective memory, which is the ability to remember to perform future activities.

6 Dec 2023

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

The genetic relationship between alcohol consumption, smoking, coffee intake, and the risk of arthritis.

6 Dec 2023

Study reveals subclinical cardiac changes in Hispanic women with history of hypertensive pregnancy disorders

The long-term cardiac effects of de novo hypertensive disorders of pregnancy.

6 Dec 2023

New study classifies CSU skin eruptions into five categories using mathematical modeling

Chronic spontaneous urticaria (CSU), a skin condition marked by sudden eruptions.

6 Dec 2023

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Researchers assessed ethnic and racial differences in novel hormonal therapy (NHT) use among advanced prostate cancer (PCa) patients.

6 Dec 2023

Irregular sleep patterns linked to cognitive decline in older adults, study shows

Study finds that short sleep duration and high variability in sleep patterns are significantly associated with cognitive impairment in older adults, highlighting the importance of consistent sleep for cognitive health.

5 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

New genetic links to coronary artery calcification uncovered, offering treatment insights

A study in Nature Cardiovascular Research identifies two new genetic loci associated with coronary artery calcification (CAC), a key indicator of atherosclerosis and coronary artery disease.

5 Dec 2023

Mediterranean diet linked to improved sperm quality

A study in the journal Nutrients finds that adherence to the Mediterranean diet positively correlates with improved sperm parameters in men. This observational cross-sectional study, involving 300 non-obese males, revealed that higher adherence to the diet is associated with better sperm motility, morphology, viability, and count, suggesting that diet can be a crucial factor in male fertility.

5 Dec 2023

Study challenges link between proton pump inhibitors and kidney disease risk

A study in Scientific Reports investigates the association between proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RA) use on chronic kidney disease (CKD) risk.

5 Dec 2023

Medical Condition News

New drug combo fights breast cancer with brain metastases

MedUni Vienna scientists discover new pain medication with fewer side effects

Couples often share high blood pressure, study finds

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Twice daily electrical stimulation boosts brain plasticity and improves memory in Alzheimer's patients

Music could hold the key to developing effective mental health interventions

Orbitofrontal cortex holds clues for understanding and preventing depression

Housing instability heightens Alzheimer's risk in veterans

Risk factors for the development of freezing of gait in Parkinson’s disease patients

Anti-obesity medications may offer survival benefits for osteoarthritis patients

Brain stimulation offers promise for prospective memory deficits in schizophrenia

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

Study reveals subclinical cardiac changes in Hispanic women with history of hypertensive pregnancy disorders

New study classifies CSU skin eruptions into five categories using mathematical modeling

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Irregular sleep patterns linked to cognitive decline in older adults, study shows

Sympathetic nervous system and immune interplay: Key to metabolic regulation

New genetic links to coronary artery calcification uncovered, offering treatment insights

Mediterranean diet linked to improved sperm quality

Study challenges link between proton pump inhibitors and kidney disease risk

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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