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Researchers find new genes that contribute to hypoplastic left heart syndrome

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants.

17 Jul 2023

Research shows redlining's long-term impact on cardiovascular health of Black adults

The risk of heart failure in the present day was higher among Black adults who lived in U.S. zip codes historically impacted by redlining, according to research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

17 Jul 2023

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

People with Down syndrome, the condition caused by an extra copy of chromosome 21, or trisomy 21, display chronic dysregulation of their immune system, which can contribute to high rates of autoimmune conditions and severe complications from respiratory infections.

17 Jul 2023

Black patients with ICDs have higher rate of post-implant cardiac events and risk of death

Black patients with implantable cardioverter defibrillators (ICDs) have a significantly higher burden of disease than white patients with the same device, according to a new study from University of Rochester Medical Center (URMC) cardiology researchers.

17 Jul 2023

New insights into dendritic cell biology could lead to improved cancer therapies

The cells of the immune system circulate mainly in the blood and migrate into the body's tissues after an inflammation. Some types of immune cells, however, are permanently located in the tissues, where they come together to form three-dimensional networks.

17 Jul 2023

Donanemab may offer new hope for people with early Alzheimer's disease

The data reported today by Eli Lilly from the TRAILBLAZER-ALZ 2 clinical trial of donanemab in early symptomatic Alzheimer's disease demonstrate an important advancement in Alzheimer's research and treatment.

17 Jul 2023

COVID-19 vaccines saved lives of older adults with dementia in long-term care

Deaths among older adults with dementia fell starkly in nursing homes and long-term care centers after COVID-19 vaccinations became available, yet remained high for those living at home, according to a new study led by UC San Francisco.

17 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

Donanemab shows promise in slowing Alzheimer's disease

With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease.

17 Jul 2023

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research directed by Johns Hopkins investigators.

17 Jul 2023

Impact of the 2022 European heat wave: Over 60,000 deaths recorded

Researchers estimate mortality due to heat in Europe in the summer of 2022.

17 Jul 2023

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

Researchers examined the association between antidrug antibodies and the response to treatments for rheumatoid arthritis.

17 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Infection-induced cognitive decline: Mechanisms and potential treatments

Biological agents threaten people's life through different ways, one of which lies in the impairment of cognition.

17 Jul 2023

First-ever county-level estimates of Alzheimer's prevalence released at AAIC 2023

The first-ever county-level estimates of the prevalence of people with Alzheimer's dementia — in all 3,142 United States counties — were released today at the Alzheimer's Association International Conference 2023, in Amsterdam, Netherlands, and online.

17 Jul 2023

New EULAR points-to-consider can help identify people at risk of psoriatic arthritis

The transition from psoriasis to PsA - and the early diagnosis of PsA - is of considerable scientific and clinical interest. People typically have psoriatic skin disease for a decade or more before they begin to experience the joint involvement of PsA.

17 Jul 2023

Medical Condition News

Researchers find new genes that contribute to hypoplastic left heart syndrome

Research shows redlining's long-term impact on cardiovascular health of Black adults

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

Black patients with ICDs have higher rate of post-implant cardiac events and risk of death

New insights into dendritic cell biology could lead to improved cancer therapies

Donanemab may offer new hope for people with early Alzheimer's disease

COVID-19 vaccines saved lives of older adults with dementia in long-term care

Study highlights the potential of cell replacement therapy for Huntington's disease

Donanemab shows promise in slowing Alzheimer's disease

Three-pronged combination immunotherapy shows promise for pancreatic cancer patients

Impact of the 2022 European heat wave: Over 60,000 deaths recorded

Are antidrug antibodies reducing the effectiveness of rheumatoid arthritis treatment?

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Infection-induced cognitive decline: Mechanisms and potential treatments

First-ever county-level estimates of Alzheimer's prevalence released at AAIC 2023

New EULAR points-to-consider can help identify people at risk of psoriatic arthritis

What is the relative burden of oncologic and nononcologic mortality among long-term survivors of cancer in the US?

The role of airway epithelium: insights into asthma and COPD pathogenesis

Machine learning's potential for rapid LRTI diagnosis

New agreement to facilitate genetic diagnosis of hereditary retinal dystrophies

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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