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CT scans better at predicting a middle-aged person's heart disease risk than genetics

CT scans are better at predicting a middle-aged person's risk for a heart disease, such as a heart attack, than genetics, reports a new Northwestern Medicine study.

23 May 2023

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation.

23 May 2023

New white paper summarizes the published outcome data for Transoral Incisionless Fundoplication

A new white paper by the American Foregut Society (AFS) summarizes the published outcome data for Transoral Incisionless Fundoplication 2.0 (TIF 2.0) and Concomitant Transoral Incisionless Fundoplication (cTIF) to date and outlines the best practice approaches and patient assessment, selection, and management using TIF 2.0 and cTIF.

23 May 2023

Global analysis paints a picture of growing low back pain cases

Analysis of over 30 years of data has shown the number of cases of low back pain is growing, with modeling suggesting by 2050, 843 million people will be affected by the condition largely due to population increases and aging of populations.

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Detecting mental disorders with data from wearables

Depression and anxiety are among the most common mental health disorders in the United States, but more than half of people struggling with the conditions are not diagnosed and treated.

23 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

Study analyzes the relationship between tobacco use and cancer-related symptom burden

In a recent study, current smoking and vaping were associated with a higher burden of symptoms among adult cancer survivors, but these symptoms were not related to survivors' desire to quit smoking.

23 May 2023

Heart transplants from COVID-19 donors: Mixed outcomes revealed in early analysis

In a recent study published in the Journal of the American College of Cardiology, researchers investigated coronavirus disease 2019 (COVID-19)-infected donor use, donor and recipient characteristics, and early post-heart transplantation (HT) outcomes in the United States (US).

23 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

It's well-known that people with Type 2 diabetes are at an increased risk of developing Alzheimer's disease, but the reason why isn't fully understood and is an area of current research.

22 May 2023

Unpacking negative body talk: Fat talk holds stronger impact on mental health, while old talk still raises concerns

Research investigates the impact of "old talk" (negative age-related body talk) on mental health and quality of life, highlighting its limited exploration compared to "fat talk." The study examines the contribution of old talk and fat talk to negative outcomes, considering their correlation and interaction with age.

22 May 2023

High HDL-C levels and cardiovascular risks - what you need to know!

Research paper investigates the relationship between very high levels of high-density lipoprotein cholesterol (HDL-C) and cardiovascular outcomes in the general population. The study reveals that while men with high HDL-C face an increased risk of all-cause death and cardiovascular death, this association is not observed in women without coronary artery disease.

22 May 2023

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

research paper presents a perspective on tackling the healthcare challenge of Alzheimer's disease (AD) by shifting focus to pre-dementia stages and advocating for personalized medicine through improved diagnosis, prediction, and prevention strategies, empowering patients to actively manage their health and delay the onset of dementia.

22 May 2023

Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Researchers identify brain signatures for chronic pain in a small group of individuals

For the first time, researchers have recorded pain-related data from inside the brain of individuals with chronic pain disorders caused by stroke or amputation (phantom limb pain).

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

$OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women$

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

The commonly used Fracture Risk Assessment Tool (FRAX), which includes self-identified race and ethnicity information, and the Osteoporosis Self-Assessment Tool (OST), which does not, had suboptimal performance in determining major osteoporotic fracture risk across racial/ethnic categories in younger postmenopausal women.

22 May 2023

Improved version of leadless pacemaker will soon be available for all patients

Every year more than one million people receive a pacemaker. Until now, leadless versions were only available for 20% of these patients.

22 May 2023

Medical Condition News

CT scans better at predicting a middle-aged person's heart disease risk than genetics

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

New white paper summarizes the published outcome data for Transoral Incisionless Fundoplication

Global analysis paints a picture of growing low back pain cases

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Detecting mental disorders with data from wearables

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Study analyzes the relationship between tobacco use and cancer-related symptom burden

Heart transplants from COVID-19 donors: Mixed outcomes revealed in early analysis

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Metabolic sensors may play a role in the development of Alzheimer's disease, study suggests

Unpacking negative body talk: Fat talk holds stronger impact on mental health, while old talk still raises concerns

High HDL-C levels and cardiovascular risks - what you need to know!

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

Gout unveiled as surprising culprit in neurodegenerative diseases

Researchers identify brain signatures for chronic pain in a small group of individuals

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

Improved version of leadless pacemaker will soon be available for all patients

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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