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Investigators explore possible causes for cancer recurrence after LRC

Although laparoscopic radical cystectomy (LRC) and robotic assisted radical cystectomy (RARC) continue to grow in popularity and are successful in the treatment of bladder cancer, they are still considered experimental approaches. Using data collected by the Section of Uro-Technology of the European Association of Urology (ESUT), a team of researchers found that about 5% of patients experienced unexpected relapses of cancer after LRC, even with favorable pathology.

27 Apr 2016

Review focuses on autologous cell therapy that can be applied to cardiac surgery

The combination of cell and gene therapy is rapidly raising clinical interest, although their combination has been under investigation for several decades. This is mainly due to the availability and feasibility of clinically relevant gene delivery options. This review focuses on cell therapies for heart failure and their use combined with cardiac surgery as well as with gene therapy.

27 Apr 2016

Researchers test potential positive effects of micro-injury in mice modeled with AD

Researchers testing the potential positive effects of "micro-injury" by brief insertion of a small needle into the hippocampal region of mice modeled with Alzheimer's disease (AD) have found that the procedure not only stimulated the hippocampus into regenerative activity, but also reduced β-amyloid plaques, a hallmark of AD.

27 Apr 2016

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

A minimally invasive screening for ulcerative colitis, a debilitating gastrointestinal tract disorder, using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body, according to researchers at Georgia State University.

27 Apr 2016

First small molecule targeted therapy holds promise for Usher syndrome

Usher syndrome (USH) is characterized by hearing loss or deafness at birth and progressive vision loss, and is the most common cause of inherited dual sensory deficit. No treatment is currently available to stop or slow the progression of vision or hearing loss in USH3, one of three clinical classifications for USH that are further divided into subtypes and all associated with different genes.

27 Apr 2016

Understanding need for supplemental cancer screening for women with dense breasts

In a study appearing in the April 26 issue of JAMA, Elizabeth A. Rafferty, M.D., formerly of Massachusetts General Hospital, Boston, and colleagues evaluated the screening performance of digital mammography combined with tomosynthesis (a type of imaging) compared with digital mammography alone for women with varying levels of breast density.

27 Apr 2016

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans.

From Bruker BioSpin - NMR, EPR and Imaging 27 Apr 2016

Zinc sparks help doctors choose best eggs to transfer during IVF

A stunning explosion of zinc fireworks occurs when a human egg is activated by a sperm enzyme, and the size of these "sparks" is a direct measure of the quality of the egg and its ability to develop into an embryo, according to new research from Northwestern Medicine.

26 Apr 2016

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Liver failure often occurs after an extensive hepatectomy, which is the surgical resection of the liver. While liver cell transplantation is a useful therapy for acute liver failure after massive hepatectomy, when cells are transplanted through liver portal veins raises the risk of embolization, such as the formation and movement of a blood clot, often with fatal consequences.

26 Apr 2016

Post-mortem toxicology screening has many phases

Prince's autopsy was conducted by A. Quinn Strobl, MD, FCAP, a member of the College of American Pathologists. The results are expected to take at least two weeks, perhaps as many as six full weeks. This tragedy has people asking again "Why do toxicology results take so long?"

26 Apr 2016

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

A new study produced by an interdisciplinary team led by Prof. Antonio Giordano, director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University, tracks the development process and efficacy of the Italian translation of the Derriford Appearance Scale 24, an important clinical tool in identifying quality-of-life issues for breast cancer patients, especially concerns regarding body shame, depression, anxiety, overall appearance and appearance identity.

26 Apr 2016

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Photoswitchable agents might reduce side effects of a chemotherapy. So far, photodynamic therapies have been dependent on oxygen in the tissue. But hardly any oxygen exists in malignant, rapidly growing tumors.

25 Apr 2016

First breakthrough in gene therapy against aging

In September 2015, then 44 year-old CEO of BioViva USA Inc. Elizabeth Parrish received two of her own company's experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.

25 Apr 2016

Cancer survivors at risk of death after organ transplant

People who had cancer before receiving an organ transplant were more likely to die of any cause, die of cancer or develop a new cancer than organ recipients who did not previously have cancer, a new paper has found. However, the increased risk is less than that reported in some previous studies.

22 Apr 2016

Study explores benefits of hand and shoulder surgeries performed at outpatient centers

A large study of hand and shoulder surgeries performed at a freestanding, outpatient center found few complications--0.2 percent in nearly 29,000 patients over an 11-year period. The study appears in the new issue of the Journal of Bone and Joint Surgery.

22 Apr 2016

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Pediatric researchers have devised an innovative, safe and minimally invasive procedure that helps relieve rare but potentially life-threatening airway blockages occurring in children who had surgery for congenital heart defects.

22 Apr 2016

TAVR procedure could provide improved health outcomes for inoperable patients

A novel procedure for heart valve replacement surgery could provide improved health outcomes for patients who cannot have open heart surgery, as well as being a cost effective alternative.

22 Apr 2016

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Researchers at Roswell Park Cancer Institute, in collaboration with investigators from the cooperative group SWOG, have found that use of multivitamins prior to diagnosis may reduce the risk of neuropathy in breast cancer patients treated with the class of drugs known as taxanes. The team will present their findings at the American Association for Cancer Research Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

In the South East of England, a patient experience study of 18 early stage breast cancer patients who opted for single dose intraoperative radiotherapy, found positive patient reported outcomes for this alternative to standard daily external beam radiotherapy.

21 Apr 2016

Medical Procedure News

Investigators explore possible causes for cancer recurrence after LRC

Review focuses on autologous cell therapy that can be applied to cardiac surgery

Researchers test potential positive effects of micro-injury in mice modeled with AD

ATR-FTIR spectroscopy could be effective for detecting ulcerative colitis

First small molecule targeted therapy holds promise for Usher syndrome

Understanding need for supplemental cancer screening for women with dense breasts

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

Zinc sparks help doctors choose best eggs to transfer during IVF

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Post-mortem toxicology screening has many phases

Derriford Appearance Scale 24 helps identify quality-of-life issues for breast cancer patients

New photo-switchable molecule for PDT could help treat rapidly growing tumors

First breakthrough in gene therapy against aging

Cancer survivors at risk of death after organ transplant

Study explores benefits of hand and shoulder surgeries performed at outpatient centers

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

TAVR procedure could provide improved health outcomes for inoperable patients

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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