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Human breast cell atlas unveils early changes in BRCA gene mutation carriers

Researchers at the University of Cambridge have created the world's largest catalog of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene mutations.

28 Mar 2024

Unraveling gene regulation's role in pulmonary fibrosis

Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?

28 Mar 2024

AudioCure Pharma: Novel compound AC102 restores noise-induced hearing loss in preclinical models

A single application of the novel compound AC102 almost completely restores noise-induced hearing loss in preclinical models.

28 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

New research advocates genetic screening in early onset atrial fibrillation

Although the vast majority of clinicians do not view atrial fibrillation (AF) as a genetic disorder, a White Paper in the Canadian Journal of Cardiology, published by Elsevier, analyzes the current understanding of genetics and the role of genetic testing in AF and concludes there is an increasing appreciation that genetic culprits for potentially life-threatening ventricular cardiomyopathies and channelopathies may initially present with AF.

28 Mar 2024

Dietary vitamin A shows promise in Alzheimer's disease intervention, study finds

Study explored the impact of dietary vitamin A on gut microbiota and intestinal transcriptome, revealing its potential in Alzheimer's disease (AD) pathology and cognitive functions in mice.

28 Mar 2024

Simple pre-surgical protocol can help prevent dangerous post-surgical infections

A new study published today in the American Journal of Infection Control (AJIC) demonstrates the use of a simple pre-surgical infection prevention protocol to prevent dangerous post-surgical infections.

28 Mar 2024

ATLAS: The AI revolutionizing dietetics education with virtual patients

Study showcases "Authentic Teaching and Learning Application Simulation (ATLAS)," a generative AI model designed to enhance communication skills in nutrition and dietetics students by using virtual simulated patients, offering an innovative, cost-effective alternative to traditional human-simulated patients.

28 Mar 2024

Emergency departments prove fertile ground for smoking cessation success

The Cessation of Smoking Trial in the Emergency Department (COSTED) study demonstrates that a brief intervention including e-cigarette starter kits can significantly help smokers in emergency departments quit, offering a new avenue to tackle smoking rates and associated health inequalities.

28 Mar 2024

Understanding the relationship between premenstrual symptoms and perinatal mood disorders

Women with premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) have a higher risk of perinatal depression. Conversely, women with perinatal depression have a higher risk of developing premenstrual disorders.

28 Mar 2024

Synthetic gut lining developed for microbiome research

A team of Penn State researchers has developed a new synthetic material that could enable scientists to more easily study how microorganisms interact with the gastrointestinal (GI) system.

28 Mar 2024

Using microbiota analysis for health and disease management

The human body harbors approximately 30 trillion microbes, known collectively as the microbiota.

28 Mar 2024

Study provides a hopeful direction for the management of penile squamous cell carcinoma

In a recent multi-center study published in the Journal of the National Cancer Institute, researchers examined the effects of neoadjuvant chemotherapy (NAC) on patients suffering from locally advanced penile squamous cell carcinoma (PSCC).

28 Mar 2024

Rethinking PrEP's role in prevention of sexually transmitted infections

In their research article published in Eurosurveillance, von Schreeb et al. challenge existing assumptions regarding the relationship between the use of HIV pre-exposure prophylaxis (PrEP) and the incidence of bacterial sexually transmitted infections (STI).

28 Mar 2024

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show March 28 in the journal Stem Cell Reports.

28 Mar 2024

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some patients.

28 Mar 2024

New imaging technique maps oxygen movement in the brain

The human brain consumes vast amounts of energy, which is almost exclusively generated from a form of metabolism that requires oxygen.

28 Mar 2024

Accredited hospitals demonstrate better outcomes for patients undergoing rectal cancer surgery

Hospitals accredited by the American College of Surgeons National Accreditation Program for Rectal Cancer demonstrate significantly better outcomes for patients undergoing rectal cancer surgery compared to non-accredited hospitals, according to a new study published in the Journal of the American College of Surgeons.

28 Mar 2024

Study finds changing trends in arterial disease risk among diabetics

There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to studies at the University of Gothenburg.

28 Mar 2024

Medical Research News

Human breast cell atlas unveils early changes in BRCA gene mutation carriers

Unraveling gene regulation's role in pulmonary fibrosis

AudioCure Pharma: Novel compound AC102 restores noise-induced hearing loss in preclinical models

Genetic and lifestyle factors linked to brain network aging, study reveals

Predicting treatment response in common blood cancer with DNA methylation profiling

New research advocates genetic screening in early onset atrial fibrillation

Dietary vitamin A shows promise in Alzheimer's disease intervention, study finds

Simple pre-surgical protocol can help prevent dangerous post-surgical infections

ATLAS: The AI revolutionizing dietetics education with virtual patients

Emergency departments prove fertile ground for smoking cessation success

Understanding the relationship between premenstrual symptoms and perinatal mood disorders

Synthetic gut lining developed for microbiome research

Using microbiota analysis for health and disease management

Study provides a hopeful direction for the management of penile squamous cell carcinoma

Rethinking PrEP's role in prevention of sexually transmitted infections

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

New imaging technique maps oxygen movement in the brain

Accredited hospitals demonstrate better outcomes for patients undergoing rectal cancer surgery

Study finds changing trends in arterial disease risk among diabetics

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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