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CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, describes a link between positive antiphospholipid antibodies and an increased risk of future cardiovascular disease in patients with systemic lupus erythematosus (SLE).

7 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies.

7 Nov 2023

$Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis$

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Researchers will present the first-ever study of fractures and calcium pyrophosphate deposition disease at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

Researchers discover a new link between obesity and neurodegenerative disorders

Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease.

7 Nov 2023

Common liver disease expected to rise sharply in next 25 years

The most common form of chronic liver disease is expected to steadily rise over the next 25 years, adding significant burden to the medical system as a new model predicts nearly twice as many liver cancers and almost triple the need for liver transplantation by 2050, according to a study scheduled for presentation at The Liver Meeting, held by the American Association for the Study of Liver Diseases.

7 Nov 2023

Suspected bronchiectasis linked to increased mortality in smokers

Bronchiectasis, a condition defined by widened lung airways, cough and sputum production, and frequent infections, often presents along with chronic obstructive pulmonary disease (COPD). This overlap is associated with airflow obstruction and higher mortality in adults.

7 Nov 2023

Blood tests can detect inflammatory bowel disease years before symptoms appear

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

7 Nov 2023

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

Physicians who care for pregnant women have long sought to identify which of their patients would most likely benefit from monitoring of their fetus's heart rate to catch early signs of their unborn child developing heart problems tied to the mother's immune system.

7 Nov 2023

BMI should not be used to determine eligibility for gender-affirming chest surgery

Body mass index, or BMI, is a person's mass (weight) in kilograms divided by the square of their height in meters.

7 Nov 2023

How glucose restriction makes lung cancer cells more aggressive

One of the hallmarks of cancer cell development is its dependence on sugar, especially glucose, to grow and divide.

7 Nov 2023

Diagnosing early-stage lung cancer with CT screening improves survival rate

Diagnosing early-stage lung cancer with low-dose computed tomography (CT) screening drastically improves its cure rate measured over a 20-year period, according to a large-scale international study by Mount Sinai researchers published in Radiology.

7 Nov 2023

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes.

7 Nov 2023

Study reveals how doctors' communication style impacts obesity treatment outcomes

How doctors communicate with patients with obesity can have a significant impact on their weight loss success, according to a new University of Oxford study published today in Annals of Internal Medicine.

7 Nov 2023

Study shows why only a subset of individuals exposed to trauma develop PTSD

A study by researchers at EPFL shows why only a subset of individuals exposed to trauma develop posttraumatic stress disorder (PTSD).

7 Nov 2023

Study shows link between food insecurity and liver disease in teens

Teens from low-income families experiencing food insecurity are developing the most common form of liver disease twice as often as those who have easier access to food, likely because they rely on low-cost, ultra-processed foods, according to a study scheduled for presentation at The Liver Meeting, held by the American Association for the Study of Liver Diseases.

7 Nov 2023

$3.9 million grant supports research on feeding intolerance in preterm infants

For infants, especially those born prematurely, nutrient absorption and proper development go hand in hand.

7 Nov 2023

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

According to new research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, continuing tumor necrosis factor inhibitors during pregnancy is not associated with worse fetal or obstetric outcomes and may reduce the risk of severe maternal infections during pregnancy (Abstract #0477).

7 Nov 2023

New quantitative analysis of how flu viruses evolved may help predict future strains

Simon Fraser University researchers studying the evolutionary history of flu viruses have found that a new quantitative analysis of how they evolved may help predict future strains.

7 Nov 2023

Medical Research News

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

Study finds doubled risk of fractures in patients with acute calcium pyrophosphate crystal arthritis

Researchers discover a new link between obesity and neurodegenerative disorders

Common liver disease expected to rise sharply in next 25 years

Suspected bronchiectasis linked to increased mortality in smokers

Blood tests can detect inflammatory bowel disease years before symptoms appear

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

BMI should not be used to determine eligibility for gender-affirming chest surgery

How glucose restriction makes lung cancer cells more aggressive

Diagnosing early-stage lung cancer with CT screening improves survival rate

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

Study reveals how doctors' communication style impacts obesity treatment outcomes

Study shows why only a subset of individuals exposed to trauma develop PTSD

Study shows link between food insecurity and liver disease in teens

$3.9 million grant supports research on feeding intolerance in preterm infants

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

New quantitative analysis of how flu viruses evolved may help predict future strains

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

Data management challenges in scientific research

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