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Non-traditional gene fusions in luminal breast cancer: A new target for therapy

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

COVID-19 vaccination in low- and middle-income countries should complement routine childhood vaccines

COVID-19 vaccines are effective against severe cases of the disease in children and adolescents, according to a review.

21 Aug 2023

Study finds no link between short-term immunosuppressant use and cancer

Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published today in the journal BMJ Oncology.

21 Aug 2023

Time-restricted feeding may correct the circadian disruptions in Alzheimer's disease

One of the hallmarks of Alzheimer's disease is disruption to the body's circadian rhythm, the internal biological clock that regulates many of our physiological processes.

21 Aug 2023

Gene therapy repairs neural connections in mice with Hurler syndrome

A new study from the University of Minnesota is the first to demonstrate the ability for gene therapy to repair neural connections for those with the rare genetic brain disorder known as Hurler syndrome.

21 Aug 2023

Michael Bloom receives funding to study the impact of PFAS exposure on weight loss

Michael Bloom, Associate Professor, Global and Community Health, received $158,900 from the National Institutes of Health for the project: "Impact of Exposure to Perfluoroalkyl Substances on Weight Loss: A Pilot Study of Hispanic Children with Overweight/Obesity Participating in a Community-based Weight Loss Intervention Program."

21 Aug 2023

Global team of experts outlines roadmap for human skin cell atlas

As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking.

21 Aug 2023

Sleep dysfunction is underreported and underrecognized in Huntington's disease

A good night's sleep is essential for everyone. In individuals with Huntington’s disease (HD), sleep disturbances constitute an additional burden that may exacerbate disease outcomes and impact patients’ quality of life.

21 Aug 2023

Insurance coverage for implantable penile prostheses varies by type of insurance

Implantable penile prostheses (IPPs) are an established treatment option for erectile dysfunction (ED), and are covered by insurance in about 80% of cases, reports a paper in the September issue of Urology Practice®, an Official Journal of the American Urological Association (AUA).

21 Aug 2023

Zebrafish model could help unlock Parkinson's disease mechanisms

Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's.

21 Aug 2023

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

Astronauts' bone marrow fat can help replenish red blood cells and bone after space travel

A study of 14 astronauts suggests that while space travel depletes red blood cells and bone, the body can eventually replenish them back on Earth with the help of fat stored in the bone marrow.

21 Aug 2023

Anti-estrogenic therapies can suppress growth of ER-negative cancers

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

21 Aug 2023

New DNA-based anticoagulant could treat heparin-induced thrombocytopenia

Various medical circumstances, including heart attacks and extreme cases of COVID-19, necessitate the use of anticoagulants, medicines that prevent blood clots

21 Aug 2023

Depression survivors spend more time processing negative information

People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to research published by the American Psychological Association.

21 Aug 2023

Alcohol-associated bowel disease: A review of the literature

Alcohol consumption is a significant risk factor for gastrointestinal diseases, including cancer. Alcohol can damage the gastrointestinal tract in several ways.

21 Aug 2023

COVID-19 infection linked to increased risk of high blood pressure

An analysis of electronic medical records for more than 45,000 people found that COVID-19 infection was significantly associated with the development of high blood pressure, according to new research published today in Hypertension, an American Heart Association journal.

21 Aug 2023