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Funding from Breast Cancer Now supports research into new drugs for secondary breast cancer in the bone

Researchers are testing new combinations of drugs to treat breast cancer that’s spread to the bone, thanks to funding from Breast Cancer Now.

25 Aug 2023

New drug could transform treatment of brain tumors in younger people

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

25 Aug 2023

Voluntary collective isolation ineffective in preventing COVID-19 spread among Indigenous populations

Indigenous Peoples have suffered disproportionally from the ongoing COVID-19 pandemic. Systemic factors including lack of sovereignty, limited infrastructure and discrimination in local health care systems make Indigenous populations vulnerable to infectious diseases.

24 Aug 2023

Cholesterol loss in inner ear linked to age-related hearing loss

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

24 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

Anesthesiologists can play a greater role in managing patients with substance use disorders

As use and misuse of alcohol, opioids, and psychostimulants continues to increase, anesthesiologists can become a more integral part of the care team managing patients with a Substance Use Disorder (SUD), according to a series of three articles published in the September issue of Anesthesia & Analgesia, the official journal of the International Anesthesia Research Society.

24 Aug 2023

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Alcohol-associated liver disease accounts for 50% of liver-related deaths, and its rates are rising worldwide.

24 Aug 2023

Certain gut conditions associated with higher risk of Parkinson's disease diagnosis

Certain gut problems, such as constipation, difficulty swallowing, and irritable bowel syndrome (IBS), may be early warning signs of the neurological condition Parkinson's disease, suggests research published online in the journal Gut.

24 Aug 2023

People over 60s with the unhealthiest lifestyles more likely to require nursing home admission

Over 60s with the unhealthiest lifestyles are significantly more likely to require admission to a nursing home than their peers with the healthiest lifestyles, suggest the findings of a large population study published online in the Journal of Epidemiology & Community Health.

24 Aug 2023

Maternal emulsifier consumption associated with mild health risks for offspring

A new study in mice shows that consuming emulsifiers, a common ingredient in ultra-processed human foods during pregnancy or breast-feeding is associated with mild health risks for offspring.

24 Aug 2023

FDA approves more drugs based on single trials and less public disclosure of results

The U.S. Food and Drug Administration is approving more novel pharmaceutical drugs based on single clinical trials and with less public disclosure about those trials than was the norm just a few years ago, a pair of recent studies from Oregon State University found.

24 Aug 2023

Genetics and environment influence immune responses to SARS-CoV-2

During the COVID-19 pandemic, the clinical spectrum observed among people infected with SARS-CoV-2 ranged from asymptomatic carriage to death.

24 Aug 2023

Women with pre-eclampsia undergo accelerated aging during pregnancy

Pre-eclampsia, a life-threatening surge in blood pressure, is an enigmatic condition. Each year, it causes the deaths of more than 70,000 women worldwide. Because scientists do not know what causes it, they lack targeted strategies to treat it.

24 Aug 2023

UTMB research potentially points to an effective treatment for Lassa fever

New research out of the University of Texas Medical Branch potentially points to an effective treatment for Lassa fever, a dangerous, often fatal disease common to much of West Africa but considered a major threat to global health.

24 Aug 2023

Researchers discover new biological mechanism to regenerate and repair myelin

A study led by Dr. Hyun Kyoung Lee, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a new biological mechanism to regenerate and repair myelin, a protective sheath that insulates neuronal fibers and plays a vital role in ensuring rapid and accurate neurotransmission.

24 Aug 2023

New model predicts 10-year risk of dying from breast cancer

A team of researchers at the University of Oxford, led by the Nuffield Department of Primary Care Health Sciences, have developed a new model that reliably predicts a woman's likelihood of developing and then dying of breast cancer within a decade.

24 Aug 2023

Age-related changes in the blood system can exacerbate colon cancer

Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster.

24 Aug 2023

KAUST researchers refute challenges to targeted cancer therapy

Drugs that inhibit a key protein should offer new targeted cancer therapy for leukemia and breast cancer.

24 Aug 2023

Lung cells can be trained to counteract inflammation

Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 have been due to excessive inflammation, which results in acute lung injury.

24 Aug 2023

Neglected brain region could play a critical role in drug relapse

Researchers from Indiana University School of Medicine have discovered a neglected brain region that could play a critical role in how likely a person with drug use disorders is to relapse, even after a long withdrawal period.

24 Aug 2023