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UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

1It was a nagging mystery: A rare-disease expert at UPMC Children's Hospital of Pittsburgh had found a successful treatment for two of the deadliest symptoms of one of the more common classes of rare diseases diagnosed by newborn screenings, but one symptom--painful episodes of muscle breakdown that land victims in intensive care--persisted.

29 Jun 2021

Wayne State awarded NSF grant to investigate how viruses navigate through the mucus barrier

A research team at Wayne State University led by Ashis Mukhopadhyay, Ph.D., associate professor of physics and astronomy in the College of Liberal Arts and Sciences, received a three-year, $326,226 grant from the National Science Foundation to investigate fundamental issues related to the passage of viruses through the mucus barrier.

29 Jun 2021

New discovery could yield a potential new treatment for breast cancer

A discovery by a team of researchers, led by a Geisinger professor, could yield a potential new treatment for breast cancer.

29 Jun 2021

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Researchers at the University of Chicago and the U.S. Department of Energy's (DOE) Argonne National Laboratory have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain.

29 Jun 2021

Sleep-deprived individuals less likely to disclose information about past criminal activity

During the course of a criminal investigation, it is common for investigators to interview individuals who are exhausted and have had little sleep. While unavoidable in some cases, a new Iowa State University study found sleep disruption or deprivation may limit the amount of information provided during an interview.

29 Jun 2021

Patient-psychotherapist matching improves outcomes of mental health treatment

In first-of-its kind research led by a University of Massachusetts Amherst psychotherapy researcher, mental health care patients matched with therapists who had a strong track record of treating the patients' primary concerns had better results than patients who were not so matched.

29 Jun 2021

SARS-CoV-2 infection induces accumulation of lipids and N-proteins

Scientists from the Netherlands and the US recently studied the localization of the SARS-CoV-2 proteins in postmortem lung tissues of COVID-19 patients and in SARS-CoV-2 infected Vero cells that were processed identically. The research is posted to the bioRxiv* preprint server, prior to peer review.

29 Jun 2021

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

In the context of recent debate over the FDA's approval of aducanumab, it's refreshing to learn about a model of Alzheimer's neurodegeneration that doesn't start with the pathogenic proteins amyloid or Tau.

29 Jun 2021

Researchers figure out how to build an artificial brain from the bottom up

Rice University scientists are starting small as they begin to figure out how to build an artificial brain from the bottom up.

29 Jun 2021

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens in vital organs, such as the brain, kidney, liver and heart, it causes organ damage and, if left untreated, death. Unfortunately, the available treatment options are very limited.

29 Jun 2021

Two CU Cancer Center studies provide insights into the link between inflammation and leukemia

Two recent collaborative publications by CU Cancer Center members provide insights into how chronic inflammation can serve as a key factor in the development of leukemia and other blood cancers.

29 Jun 2021

Study highlights importance of "lived experience" provided by cancer patients in prisons

In a paper published by Research Involvement and Engagement, the University of Surrey and its partners highlight the importance and value of "lived experience" that only people in prison can provide to shape meaningful research and policy decisions.

29 Jun 2021

SARS-CoV-2 test in 20 minutes with FISH

A collaboration from the University of Oxford and the University of Warwick has led to research into a novel method of viral detection through rapid fluorescence in situ hybridization (FISH) in order to effectively detect the SARS-CoV-2 virus within 20 minutes.

29 Jun 2021

Transparent masks can facilitate communication and improve interaction, study shows

The use of transparent masks during communication increases comprehension of speech by about 10% for people with hearing loss and people with normal hearing, according to a study published in the journal Ear and Hearing.

29 Jun 2021

Study highlights need to protect physician residents, emergency care teams from physical or verbal abuse

A new study in Annals of Emergency Medicine highlights the importance of protecting physician residents--early-career doctors still in training--and emergency care teams from incidents of physical or verbal abuse.

29 Jun 2021

Lowering iron content in fat cells prevented mice from gaining excess weight

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines, UT Southwestern scientists report in a new study. The findings, published online in Cell Metabolism, could eventually lead to new strategies to protect people against obesity and related diseases.

29 Jun 2021

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

A new approach using precisely targeted, high-dose radiation to treat invasive kidney cancer proves safe, based on a clinical trial by the UT Southwestern Harold C. Simmons Comprehensive Cancer Center's kidney cancer program. The study, published in the International Journal of Radiation Oncology*Biology*Physics, could offer new hope for patients with a historically dismal condition.

29 Jun 2021

Immune response to FDA-approved vaccines is strong and potentially long-lasting

The first two COVID-19 vaccines authorized for emergency use by the Food and Drug Administration (FDA) employed a technology that had never before been used in FDA-approved vaccines.

29 Jun 2021

New drug candidate may reduce anxiety-like behavior in mice

Anxiety, commonly termed as a feeling of fear, dread, and restlessness, is a perfectly normal reaction to stressful situations. However, a state of heightened anxiety, which is the reality for thousands of people who struggle to cope with these feelings, is called anxiety disorder.

29 Jun 2021

Study finds evidence for adverse effects of COVID-19 pandemic on cancer detection, surgical treatments

A new study finds evidence for adverse effects of the COVID-19 pandemic on declines in cancer detection and surgical treatments.

29 Jun 2021

Medical Research News

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

Wayne State awarded NSF grant to investigate how viruses navigate through the mucus barrier

New discovery could yield a potential new treatment for breast cancer

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Sleep-deprived individuals less likely to disclose information about past criminal activity

Patient-psychotherapist matching improves outcomes of mental health treatment

SARS-CoV-2 infection induces accumulation of lipids and N-proteins

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

Researchers figure out how to build an artificial brain from the bottom up

New study reveals how heparan sulfate promotes amyloid deposition in various organs

Two CU Cancer Center studies provide insights into the link between inflammation and leukemia

Study highlights importance of "lived experience" provided by cancer patients in prisons

SARS-CoV-2 test in 20 minutes with FISH

Transparent masks can facilitate communication and improve interaction, study shows

Study highlights need to protect physician residents, emergency care teams from physical or verbal abuse

Lowering iron content in fat cells prevented mice from gaining excess weight

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

Immune response to FDA-approved vaccines is strong and potentially long-lasting

New drug candidate may reduce anxiety-like behavior in mice

Study finds evidence for adverse effects of COVID-19 pandemic on cancer detection, surgical treatments

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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