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Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in respiratory samples. Furthermore, the method can detect viral variants even in samples with low viral RNA or degraded viral RNA. The study is currently available on the medRxiv* preprint server.

7 Nov 2021

Pacific oyster as a weapon against SARS-CoV-2

According to an article published in the journal Reviews in Medical Virology, the effectiveness of mollusc-derived antiviral agents has been proven in many different laboratory and animal studies, while its efficacy against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been proposed by recent in silico studies.

7 Nov 2021

New data points to major SARS-CoV-2 animal reservoir in deer in Iowa

A new study tests the hypothesis that white-tailed deer are susceptible to SARS-CoV-2 infection.

7 Nov 2021

Reducing airborne transmission of infectious respiratory viruses with portable air purifiers

A new computational study focuses on the performance of portable air purifiers based on Computational Fluid Dynamics (CFD) simulations.

7 Nov 2021

The importance of exercise for those with diabetes in the COVID era

A review aims to evaluate the effectiveness of physical activity in people with type 2 diabetes and COVID-19.

7 Nov 2021

Fast evolution of SARS-CoV-2 driven by extensive RNA deamination by host cells

A new study proposed that the RNA structure and the genome component may serve as an important basis of different deamination spectrums in SARS-CoV-2.

7 Nov 2021

Dramatic reduction in cervical cancer in the UK following the introduction of HPV vaccination

The current study assessed the impact of HPV vaccination on the rates of cervical cancer and cervical carcinoma in situ.

7 Nov 2021

New CDC report discusses efficacy of mRNA COVID vaccines in immunocompromised

The U.S. CDC reports the observed efficacy among the immunocompromised population following vaccination with mRNA vaccines against SARS-CoV-2.

7 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

A recent study assesses the boost in antibodies against SARS-CoV-2)variants post-vaccination in plasma samples from previously infected COVID-19 patients.

7 Nov 2021

Study examines benefits of SGLT2 inhibitors in individuals with type 1 diabetes

In addition to lowering blood sugar levels, diabetes drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors can provide kidney- and cardiovascular-related benefits for people with type 2 diabetes.

7 Nov 2021

SARS-CoV-2 infection amplifies immune system–related differences in dialysis, kidney transplant patients

People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19.

7 Nov 2021

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

A new study by researchers at Hospital for Special Surgery (HSS) in New York City demonstrates over half of patients with rheumatic diseases who contracted COVID-19 during the pandemic and completed a COVID-19 survey, experienced so-called "long-haul" COVID, or prolonged symptoms of the infection, including loss of taste or smell, muscle aches and difficulty concentrating, for one month or longer.

7 Nov 2021

Using deductive reasoning based on particle physics' principles in aging research

Aging-US published "Applying deductive reasoning and the principles of particle physics to aging research" which reported that aging research currently lacks a common conceptual framework, and one challenge in establishing it is the fact that aging is a highly complex process.

7 Nov 2021

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious cardiotoxicities including myocarditis. ICI-induced myocarditis represents a new clinical syndrome because of the novelty and considerable usage of ICIs.

7 Nov 2021

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Despite its discovery nearly 100 years ago, insulin's list price has been going up, not down, with trade secrets and other protections preventing researchers from pinpointing who is receiving profits from its sale.

7 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

7 Nov 2021

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Polybrominated diphenyl ethers, or PBDEs, are a class of fire-retardant chemicals that are ubiquitous. They are found on upholstery, carpets, curtains, electronics, and even infant products.

7 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

Medical Research News

Highly-sensitive PCR-based method to detect SARS-CoV-2 variants

Pacific oyster as a weapon against SARS-CoV-2

New data points to major SARS-CoV-2 animal reservoir in deer in Iowa

Reducing airborne transmission of infectious respiratory viruses with portable air purifiers

The importance of exercise for those with diabetes in the COVID era

Fast evolution of SARS-CoV-2 driven by extensive RNA deamination by host cells

Dramatic reduction in cervical cancer in the UK following the introduction of HPV vaccination

New CDC report discusses efficacy of mRNA COVID vaccines in immunocompromised

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Convalescent plasma post-vaccination increases binding and neutralizing antibodies against SARS-CoV-2 variants

Study examines benefits of SGLT2 inhibitors in individuals with type 1 diabetes

SARS-CoV-2 infection amplifies immune system–related differences in dialysis, kidney transplant patients

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

Using deductive reasoning based on particle physics' principles in aging research

Some immune checkpoint inhibitors can cause serious arrhythmias and myocarditis

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Therapeutics that target ceramides may help treat cardiometabolic disease

Deletion of ABI3 gene in the brain may increase risk of developing Alzheimer’s disease

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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