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Large Israeli study offers detailed look at safety profile of mRNA vaccine against SARS-CoV-2

A deep look into a nationwide mass vaccination setting in Israel revealed that the BNT162b2 (Pfizer–BioNTech) vaccine is not linked with an elevated risk of a majority of the adverse events under study, with the exception of myocarditis. However, even that potentially severe adverse event is much more pervasive following the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), found a new study published in the New England Journal of Medicine (NEJM).

30 Aug 2021

Next-gen COVID vaccine to make persistent neutralizing antibodies

Presently, there is a need to develop improved versions of COVID-19 vaccines that are effective against the SARS-CoV-2 variants of concern (VOC) and can confer long-term protection. Considering the need of the hour, scientists from the University of Sydney in Australia have generated a new COVID-19 vaccine CoVac-II and evaluated its effect against COVID-19 strains. The findings from this study are published on the bioRxiv* preprint server while awaiting peer review.

30 Aug 2021

Can molecular mimicry impact fertility in female COVID-19 patients?

There exists a possibility that COVID-19 can also affect the reproductive function in the body, which can lead to infertility in infected patients. A study published in the American Journal of Reproductive Immunology explored the impact of SARS-CoV-2 infection on reproductive functions and fertility.

30 Aug 2021

Modeling of COVID-19 seroprevalence and resurgence in Canada

Despite increased vaccine distribution and a significant decrease in the number of COVID-19 cases in Canada, the future of the pandemic is still a major concern, based on the possibility of a resurgence in the short term as well as long term and an understanding of the future of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity. It is not clear if the Canadian population will reach herd immunity or if there is a risk of future resurgence of the virus in the Fall or Winter.

30 Aug 2021

COVID-19 in Virginia: Beliefs drive behavior

A new paper examines this phenomenon as it relates to the state of Virginia to outline lessons to be learned from this debacle of pandemic management.

29 Aug 2021

Have SARS-CoV-2 symptoms changed in the UK population over time?

A new paper compares changes in the symptoms due to COVID-19 over the course of the pandemic.

29 Aug 2021

What might the third wave of COVID-19 in India look like?

A new study applies mathematical modeling to understand what the third wave of the pandemic might look like in India.

29 Aug 2021

Assessing the risks of thrombotic events post vaccination with ChAdOx1 and BNT162b2 vaccines in England

Researchers aim to better understand the population-level thrombotic risks post COVID-19 vaccination with both the ChAdOx1-S and BNT162b2 vaccines.

29 Aug 2021

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

Announcing a new article publication for Zoonoses journal. In this article the authors Jianqin Liang, Guizeng Liu, Shuzhuang Yu, Yang Yang, Yanchun Li, Hongli Tian, Zhe Chen and Wenping Gong The Eighth Medical Center of PLA General Hospital, Beijing, China and Nanpi County People's Hospital, Hebei, China discuss dynamic changes in chest CT images over 167 days in 11 patients with COVID-19.

28 Aug 2021

Study reveals measures to tackle musical COVID-19 transmission

As the COVID-19 pandemic swept the globe in 2020, musicians around the world were desperate for the answers to two pressing questions: Can playing musical instruments transmit COVID-19? And if so, what can be done?

28 Aug 2021

Moderate-vigorous physical activity found to be the most efficient at improving fitness

In the largest study performed to date to understand the relationship between habitual physical activity and physical fitness, researchers from Boston University School of Medicine (BUSM) have found that higher amount of time spent performing exercise (moderate-vigorous physical activity) and low-moderate level activity (steps) and less time spent sedentary, translated to greater physical fitness.

28 Aug 2021

Young children picked up extra weight during the COVID-19 pandemic

A Kaiser Permanente study of nearly 200,000 children showed that children gained excess weight during the COVID-19 pandemic, especially those between 5 and 11 years old. The study was published in the Journal of the American Medical Association.

28 Aug 2021

Cognitive function of older adults could be improved through multidomain lifestyle interventions

Aging-US published "Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial" which reported that in an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI, the home-based MI, or the control group receiving general health advice.

28 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

More than one-third of physician assistants suffer from burnout, study reports

More than one-third of physician assistants meet criteria for burnout, suggests a study in the September issue of JAAPA, Journal of the American Academy of PAs. The journal is published in the Lippincott portfolio by Wolters Kluwer.

28 Aug 2021

Exercise reduces the amount of calories burned at rest in obese people, study finds

Exercise reduces the amount of calories burned at rest in people with obesity, according to a new study by researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences and the University of Roehampton.

28 Aug 2021

Study may pave way for new treatment strategies to limit the progression of solid tumors

Researchers at the University of British Columbia's faculty of medicine and BC Cancer Research Institute have uncovered a weakness in a key enzyme that solid tumour cancer cells rely on to adapt and survive when oxygen levels are low.

28 Aug 2021

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.

28 Aug 2021

Neurons in visual cortex of the brain change their responses over time, research reveals

New research from Washington University in St. Louis reveals that neurons in the visual cortex - the part of the brain that processes visual stimuli - change their responses to the same stimulus over time.

28 Aug 2021

Pfizer COVID-19 jab side effects likely to be mild to moderate in extremely vulnerable 12-15 year olds

The side effects of the Pfizer-BioNTech jab against COVID-19 are likely to be mild to moderate and clear up quickly in 12-15 year olds at high risk of complications from the infection because of certain coexisting conditions, reveals a small study accepted for publication in the Archives of Disease in Childhood.

28 Aug 2021

Medical Research News

Large Israeli study offers detailed look at safety profile of mRNA vaccine against SARS-CoV-2

Next-gen COVID vaccine to make persistent neutralizing antibodies

Can molecular mimicry impact fertility in female COVID-19 patients?

Modeling of COVID-19 seroprevalence and resurgence in Canada

COVID-19 in Virginia: Beliefs drive behavior

Have SARS-CoV-2 symptoms changed in the UK population over time?

What might the third wave of COVID-19 in India look like?

Assessing the risks of thrombotic events post vaccination with ChAdOx1 and BNT162b2 vaccines in England

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

Study reveals measures to tackle musical COVID-19 transmission

Moderate-vigorous physical activity found to be the most efficient at improving fitness

Young children picked up extra weight during the COVID-19 pandemic

Cognitive function of older adults could be improved through multidomain lifestyle interventions

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

More than one-third of physician assistants suffer from burnout, study reports

Exercise reduces the amount of calories burned at rest in obese people, study finds

Study may pave way for new treatment strategies to limit the progression of solid tumors

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Neurons in visual cortex of the brain change their responses over time, research reveals

Pfizer COVID-19 jab side effects likely to be mild to moderate in extremely vulnerable 12-15 year olds

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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