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Researchers identify common epitopes across SARS-CoV-2 viral variants

While several COVID-19 vaccine candidates have been developed and deployed to arrest the spread of SARS-CoV-2, concern among scientists and public health authorities is mounting over the immunity escape potential of emerging viral variants. To address this problem, a group of scientists in Germany has undertaken research to identify molecular targets across viral variants to aid in the development of second and third-generation vaccines and novel therapeutics.

1 Jun 2021

New method helps identify rare genetic disease that affects brain development

Rare disease experts detail the first results of an unprecedented collaboration to diagnose people living with unsolved cases of rare diseases across Europe.

1 Jun 2021

How the decline in fish biodiversity is affecting human nutrition

Researchers have found that biomass compensation may impair the health of populations that depend on fish for their daily nutritional intake.

1 Jun 2021

Can depression increase the likelihood of rapid kidney function decline?

In a recent study, the presence of depressive symptoms in normally healthy individuals was found to correlate with rapid kidney function decline.

1 Jun 2021

Overconfidence in judgment increases the susceptibility to believing misinformation

New findings demonstrate that the likelihood of falling victim to false news increases with the belief they can distinguish false from real news.

1 Jun 2021

Vitamin D may be ineffective in protecting against COVID-19

A study published in PLOS Medicine suggests that genetic evidence does not support vitamin D as a protective measure against COVID-19.

1 Jun 2021

Better late than never: clinical guidelines are too late to screen for prostate cancer

Men with a family history of prostate cancer may need to be screened up to 11 years before guidelines require.

1 Jun 2021

Using Sotrovimab to treat COVID-19 early

A new study published on the medRxiv* preprint server hypothesized that a monoclonal antibody that has the capability to neutralize all sarbecoviruses could also be used to target a highly conserved epitope. This conserved sequence has a high probability of remaining unchanged in SARS-CoV-2 variants.

31 May 2021

SARS-CoV-2 variants have higher transmissibility and a longer infectious period

Researchers analyzed data on three variants of concern and found that viral loads were higher and infection lasted longer for the B.1.1.7 variant. They all were more infectious than the original strain, and transmissibility also depended on population demographics.

31 May 2021

Function and regeneration of dendritic cells impaired in COVID-19

A group of researchers from Germany has investigated and analyzed circulating dendritic cells and monocyte subsets in 65 hospitalized COVID-19 patients with mild to severe presentations of the infection. A variety of patients were included in their study, from those who exhibited minor signs of acute disease to convalescents, as well as healthy controls

31 May 2021

A novel multiplexed diagnostic approach for COVID-19

Researchers developed a platform for detecting the virus directly from a patient's sample as well as the immune response through antibodies such as IgG and IgM.

31 May 2021

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

The report has recently been published on the preprint server medRxiv* by Kwong et al. (May 28th, 2021) and focused on the Pfizer-BioNTech or Moderna vaccines, confirming the supposed greater efficacy in preventing infection or severe outcomes following the administration of two doses.

31 May 2021

SARS-CoV-2 variant B.1.617 may be more transmissible and pathogenic due to spike cleavage

In a new research paper currently available on the bioRxiv* preprint server, a research group from the United Kingdom (UK) provides experimental evidence that B.1.617 lineage of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) – also known as the Indian variant of concern – shows enhanced cleavage of spike glycoprotein by furin, which can enhance its transmissibility and pathogenic traits.

31 May 2021

New material can enable a near-perfect merger between machines and the human body

Researchers at DTU Health Tech have developed a new material that can facilitate a near-perfect merger between machines and the human body for diagnostics and treatment.

31 May 2021

Tai chi mirrors the beneficial effects of conventional exercise, study shows

A new study shows that tai chi mirrors the beneficial effects of conventional exercise by reducing waist circumference in middle-aged and older adults with central obesity. The study was done by investigators at the University of Hong Kong, The Chinese University of Hong Kong; Chinese Academy of Sciences; and UCLA.

31 May 2021

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found.

31 May 2021

Diabetes remission diet can provide blood pressure control, reduce the need for anti-hypertensive drugs

New research has shown that if people achieve and maintain substantial weight loss to manage their type 2 diabetes, many can also effectively control their high blood pressure and stop or cut down on their anti-hypertensive medication.

31 May 2021

Researchers discover a new and unique form of ALS

In a study of 11 medical-mystery patients, an international team of researchers led by scientists at the National Institutes of Health and the Uniformed Services University discovered a new and unique form of amyotrophic lateral sclerosis (ALS).

31 May 2021

Researchers repurpose pre-existing anti-SARS-CoV antibody to develop potent neutralizing antibody against SARS-CoV-2

A team of scientists from the United States has recently engineered a pre-existing anti-severe acute respiratory syndrome coronavirus (SARS-CoV) neutralizing antibody to increase its binding affinity for the spike receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The engineered antibody demonstrates high potency in neutralizing SARS-CoV-2 and preventing infection in animals.

31 May 2021

More than a third of heat-related deaths attributable to human-induced global warming

Between 1991 and 2018, more than a third of all deaths in which heat played a role were attributable to human-induced global warming, according to a new article in Nature Climate Change.

31 May 2021

Medical Research News

Researchers identify common epitopes across SARS-CoV-2 viral variants

New method helps identify rare genetic disease that affects brain development

How the decline in fish biodiversity is affecting human nutrition

Can depression increase the likelihood of rapid kidney function decline?

Overconfidence in judgment increases the susceptibility to believing misinformation

Vitamin D may be ineffective in protecting against COVID-19

Better late than never: clinical guidelines are too late to screen for prostate cancer

Using Sotrovimab to treat COVID-19 early

SARS-CoV-2 variants have higher transmissibility and a longer infectious period

Function and regeneration of dendritic cells impaired in COVID-19

A novel multiplexed diagnostic approach for COVID-19

Report on the effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in Canada

SARS-CoV-2 variant B.1.617 may be more transmissible and pathogenic due to spike cleavage

New material can enable a near-perfect merger between machines and the human body

Tai chi mirrors the beneficial effects of conventional exercise, study shows

Cognitive reappraisal may reduce compulsive drug-seeking behavior in cocaine-addicted individuals

Diabetes remission diet can provide blood pressure control, reduce the need for anti-hypertensive drugs

Researchers discover a new and unique form of ALS

Researchers repurpose pre-existing anti-SARS-CoV antibody to develop potent neutralizing antibody against SARS-CoV-2

More than a third of heat-related deaths attributable to human-induced global warming

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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