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Reduced mRNA COVID-19 vaccine response in nursing home residents

A recent study has examined the response of nursing home residents who were naïve to SARS-CoV-2 infection following vaccination by the mRNA BNT162b2 model from Pfizer-BioNTech.

24 Mar 2021

Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Researchers at the Division of Infection and Immunity, University College London, UK, have provided key insights into the characteristics of the B.1.1.7 (or UK) variant of SARS-CoV-2.

24 Mar 2021

Long-term complications are common among COVID-19 recovered individuals

A team of scientists from the United Kingdom has recently conducted a multicenter, prospective cohort study to investigate long-term consequences of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Mar 2021

Researchers develop innovative biosensor that can detect and quantitate SARS-CoV-2 infection

Researchers have generated protease-activatable fluorescent and luminescent biosensors for SARS-CoV-2 MPro (main protease) and PLPro (papain-like protease) activity, one based on “flip” GFP (FlipGFP), and the other based on circularly permuted firefly luciferase (FFluc).

24 Mar 2021

The way adolescence view their bodies can protect against weight gain

A new study from the University of Bergen (UiB) shows that the way young people view their bodies have a great impact on their BMI.

24 Mar 2021

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Being persistently lonely during midlife (ages 45-64) appears to make people more likely to develop dementia and Alzheimer's Disease (AD) later in life. However, people who recover from loneliness, appear to be less likely to suffer from dementia, compared to people who have never felt lonely.

24 Mar 2021

Cognitive decline is linked to COVID-19 lockdown, shows study

A decline in cognitive functions - such as memory, attention and decision-making - is connected to the tightest restrictions in Scotland's COVID-19 lockdown, a new peer-reviewed study has found.

24 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

A new study adds to the sum of knowledge about SARS-CoV-2, with respect to its natural and biologically significant mutations, using computational modeling of the virus-receptor interactions. Understanding how viral mutations affect the virus-host interactions is crucial for shaping proper strategies to control the virus.

24 Mar 2021

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

24 Mar 2021

New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

A new study describes the use of a combination of virtual and experimental screening protocols to identify potential inhibitors of the virus, which could lead to rapid drug development.

24 Mar 2021

Communication between the brain’s auditory and reward circuits underpins music-induced pleasure

Communication between the brain’s auditory and reward circuits is the reason why humans find music rewarding, according to new research published in JNeurosci.

24 Mar 2021

High throughput screening for COVID-19 with the VOYAGER pipette

The COVID-19 pandemic has slowed down research in many scientific areas, but for the Jain Lab in the Department of Chemical Engineering at the University of Florida, the pandemic has created an exciting opportunity to repurpose their work.

From INTEGRA Biosciences 24 Mar 2021

How do fingerprints enhance our sense of touch?

Dr. Ewa Jarocka speaks to News-Medical about our senses, and how fingerprints can enhance our sense of touch.

24 Mar 2021

Study provides details on the global burden of gallbladder and biliary tract cancer

Although cancers that occur in the gallbladder or bile ducts are rare, their rates are increasing. A recent study provides details on the burden of gallbladder and biliary tract cancer (GBTC) across 195 countries and territories from 1990 to 2017.

24 Mar 2021

Research reveals varied experiences of people involved in maternity care during COVID-19 pandemic

Doctors, midwives and midwifery students were more concerned about their exposure to COVID-19 while at work than the women receiving maternity care in the same settings, while the partners of those women reported feeling isolated because of changes to the way care was provided, new Curtin University research has found.

24 Mar 2021

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

A new preprint study led by Shawn S-C. Li from Western University in Ontario, Canada, provides evidence of epitope-specific antibody responses and designed a test to measure this in relation to disease severity and outcome after infection.

24 Mar 2021

New range of lung-on-chip technologies represent the vital properties of lung tissue

According to the National Institutes of Health, respiratory viruses are the most frequent cause of disease and death in humans, a fact highlighted by the COVID-19 pandemic. Despite the potential to cause severe disease, over 70% of viral infections remain asymptomatic.

24 Mar 2021

Study may lead to more refined approaches for head and neck cancers

By targeting an enzyme that plays a key role in head and neck cancer cells, researchers from the UCLA School of Dentistry were able to significantly slow the growth and spread of tumors in mice and enhance the effectiveness of an immunotherapy to which these types of cancers often become resistant.

24 Mar 2021

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients.

24 Mar 2021

Medical Research News

Reduced mRNA COVID-19 vaccine response in nursing home residents

Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Long-term complications are common among COVID-19 recovered individuals

Researchers develop innovative biosensor that can detect and quantitate SARS-CoV-2 infection

The way adolescence view their bodies can protect against weight gain

Persistent loneliness during midlife can increase risk of dementia, Alzheimer’s disease

Cognitive decline is linked to COVID-19 lockdown, shows study

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

New covalent and non-covalent SARS-CoV-2 inhibitors discovered in silico

Communication between the brain’s auditory and reward circuits underpins music-induced pleasure

High throughput screening for COVID-19 with the VOYAGER pipette

How do fingerprints enhance our sense of touch?

Study provides details on the global burden of gallbladder and biliary tract cancer

Research reveals varied experiences of people involved in maternity care during COVID-19 pandemic

Epitope antibody testing is effective in detecting immune responses to SARS-CoV-2

New range of lung-on-chip technologies represent the vital properties of lung tissue

Study may lead to more refined approaches for head and neck cancers

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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