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Novel gene therapy reprograms glioma cells into functional neurons

Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades.

24 Mar 2021

Research suggests toothpaste and mouthwash ingredients could help prevent SARS-CoV-2 infection

Now, new research published on the bioRxiv preprint server focuses on the effect of some typical ingredients present in commercially available mouthwashes and toothpaste on the mechanisms of SARS-CoV-2 entry into host cells.

24 Mar 2021

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

Peritoneal mesothelioma is cancer that develops in the lining of the abdomen, which is known as the peritoneum.

24 Mar 2021

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

Vaccinating health care workers resulted in an immediate and notable reduction of positive COVID-19 cases among employees, reducing the number of required isolations and quarantines by more than 90 percent, according to data at UT Southwestern Medical Center published in the New England Journal of Medicine.

24 Mar 2021

Glycans play a key role in COVID-19 infection, shows study

A research group at the RIKEN Center for Computational Science (R-CCS) has found that glycans—sugar molecules—play an important role in the structural changes that take place when the virus which causes COVID-19 invades human cells.

24 Mar 2021

New technique traces genetic and epigenetic origins of DNA to reveal hidden cancers

A new technique that can trace which tissues and organs the DNA in our blood comes from has been reported today in the open-access eLife journal.

24 Mar 2021

Embitterment with pathological intensity is as frequent as other mental disorders

Embitterment is an emotion which is known to everybody. It is a response to injustice, humiliation, and breach of trust.

24 Mar 2021

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

In a new study, published recently on the bioRxiv preprint server, researchers isolated a nanobody that potently neutralizes SARS-CoV-2, including the B.1.351 variant, and cross-neutralizes SARS-CoV. They demonstrated the therapeutic potential of the nanobody in a human ACE2 (angiotensin-converting enzyme) transgenic mouse model.

24 Mar 2021

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

The CVnCoV mRNA vaccine showed neutralizing antibody levels and completely protected mice infected with the B.1.351 variant. No viral genomes were seen in oral swabs, lungs, or brain.

23 Mar 2021

Pilot study finds Bartonella infection in the blood of people with schizophrenia

A pilot study from North Carolina State University and the University of North Carolina at Chapel Hill has found evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder.

23 Mar 2021

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Previous research identified the interferon-responsive OAS1 gene as a risk gene for Alzheimer's disease. OAS1 is an enzyme that binds to double-stranded RNA and induces the conformation to create oligoadenylates. They also activate RNase L to break down RNA.

23 Mar 2021

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

A recent study by researchers from Philadelphia, currently available on the medRxiv preprint server, shows that individuals with prior infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit substantial immune memory and develop a robust response to the first dose of an mRNA vaccine.

23 Mar 2021

COVID-19 prevention strategies may have led to a decrease in common respiratory infections

Wearing masks and physical distancing - two key infection prevention strategies implemented to stop the spread of COVID-19 - may have led to the dramatic decrease in rates of common respiratory viral infections, such as influenza.

23 Mar 2021

Temple researchers receive CHEST Foundation grant to explore racial disparities in lung function

Lung disease is the third-leading cause of death in the United States. Much of this burden is disproportionately spread across populations of non-Hispanic whites, particularly African Americans who smoke.

23 Mar 2021

Genetic study identifies sex-dependent differences in major psychiatric disorders

An analysis of sex differences in the genetics of schizophrenia, bipolar disorder and major depressive disorders indicates that while there is substantial genetic overlap between males and females, there are noticeable sex-dependent differences in how genes related to the central nervous system, immune system, and blood vessels affect people with these disorders.

23 Mar 2021

Online mindfulness practices may alleviate fear, anxiety and stress associated with COVID-19

The fear, anxiety and stress associated with the COVID-19 pandemic has taken a toll on mental health. But a new study suggests these symptoms may be alleviated through safe and convenient online mindfulness practices.

23 Mar 2021

Study examines the impact of dental coverage offered through Michigan’s Medicaid expansion

As the pandemic's economic effects drive more people to enroll in Medicaid as safety-net health insurance, a new study suggests that the program's dental coverage can improve their oral health in ways that help them seek a new job or do better at the one they have.

23 Mar 2021

Exercise increases blood flow to the brain, study shows

It's not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well. A new study by researchers at UT Southwestern shows that when older adults with mild memory loss followed an exercise program for a year, the blood flow to their brains increased.

23 Mar 2021

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

Consumption of ultra-processed foods and drink could increase the risk of developing colorectal cancer. This was the conclusion of a large study undertaken by the Barcelona Institute for Global Health, a center supported by the "la Caixa" Foundation, based on questionnaires about food behaviors completed by around 8,000 people in Spain.

23 Mar 2021

Preemies have greater risk of death from chronic diseases in adulthood

The risk of dying from heart disease, chronic lung disease or diabetes in adulthood is twice as high for preemies —premature infants — as for the general population.

23 Mar 2021

Medical Research News

Novel gene therapy reprograms glioma cells into functional neurons

Research suggests toothpaste and mouthwash ingredients could help prevent SARS-CoV-2 infection

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

Vaccination of health care workers resulted in notable reduction of COVID-19 cases

Glycans play a key role in COVID-19 infection, shows study

New technique traces genetic and epigenetic origins of DNA to reveal hidden cancers

Embitterment with pathological intensity is as frequent as other mental disorders

Potent nanobody binds SARS-CoV-2 spike in an extraordinary manner

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

Pilot study finds Bartonella infection in the blood of people with schizophrenia

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

COVID-19 prevention strategies may have led to a decrease in common respiratory infections

Temple researchers receive CHEST Foundation grant to explore racial disparities in lung function

Genetic study identifies sex-dependent differences in major psychiatric disorders

Online mindfulness practices may alleviate fear, anxiety and stress associated with COVID-19

Study examines the impact of dental coverage offered through Michigan’s Medicaid expansion

Exercise increases blood flow to the brain, study shows

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

Preemies have greater risk of death from chronic diseases in adulthood

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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