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Researchers use new approach to detect COVID-19 in wastewater

There are many ways to test municipal wastewater for signs of the virus that causes COVID-19, but scientists in Houston have determined theirs is the best yet.

23 Mar 2021

Researchers are working to speed up drug development to treat brain diseases

Though 40 million concussions are recorded annually, no effective treatment exists for them or for many other brain-related illnesses.

23 Mar 2021

Ai helps identify critical interactions for SARS-CoV-2 spike protein binding to ACE2

Recently, researchers from the US employed multiple-µs molecular dynamic simulations to compare the relative dynamics, stabilities, and energy differences between the SARS-CoV receptor-binding domain (RBD)-ACE2 and SARS-CoV-2 RBD-ACE2 complexes. The study is published on the preprint server, bioRxiv.

23 Mar 2021

Swiss research shows clusters of SARS-CoV-2 infection are rare within school classes

Researchers from Switzerland recently presented the results of a longitudinal cohort study they conducted in the city of Zurich. The prospective cohort study's key objective was to analyze the longitudinal changes in SARS-CoV-2 seroprevalence and assess the clustering of seropositive children in school classes from June to November 2020 in Zurich, Switzerland.

23 Mar 2021

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

In a paper recently uploaded to the preprint server bioRxiv by Tauzin et al. (March 18th, 2021) the ability of a single dose of mRNA vaccine to induce humoral and T cell responses against mutated variants are demonstrated and found to be reinforced in individuals with a history of COVID-19.

22 Mar 2021

Simple SARS-CoV-2 mutations allow escape from the majority of polyclonal antibodies

The group identified a single class of antibodies that target a particular epitope on the RBD of SARS-CoV-2, suggesting that the human polyclonal response to SARS-CoV-2 infection is dominated by a worryingly narrow range of antibodies that target an epitope undergoing rapid mutation.

22 Mar 2021

Survey of smokers and vapers in the U.S. during COVID

Researchers at the Massachusetts General Hospital aimed to understand the changes in cigarette and e-cigarette use behaviors among adults in the United States. They found that a third of cigarette smokers and a quarter of vape or e-cigarette users increased their use during the pandemic, mainly due to stress.

22 Mar 2021

Non-invasive scTS improves handgrip strength, motor control in people with complete tetraplegia

Kessler Foundation researchers demonstrated that spinal cord transcutaneous stimulation (scTS) combined with hand training improves upper extremity and hand function in individuals with motor and sensory compete spinal cord injury (SCI).

22 Mar 2021

Study identifies metabolic processes associated with multiple, unrelated diseases

Many older, but also increasingly younger, people suffer from several diseases at the same time. Scientists at the Berlin Institute of Health at Charité – Universitätsmedizin Berlin, together with colleagues from Munich and the United Kingdom, have now identified common risk factors that predispose to multiple even seemingly unrelated diseases.

22 Mar 2021

B.1.1.7 SARS-CoV-2 variant significantly more dangerous

Now, researchers at the University of Exeter, the NHS Foundation Trust, report a significant increase in mortality risk due to the B.1.1.7 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant.

22 Mar 2021

Most cancer patients with COVID-19 produce antibodies at a rate comparable to general population

Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population--but their ability to do so depends on their type of cancer and the treatments they've received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of Medicine.

22 Mar 2021

New research could help predict acute reactions to psychedelic drugs

As psychedelics gain ground as a potential therapy for mental health disorders, there remains a pressing concern that patients in clinical trials may have adverse effects to the drugs.

22 Mar 2021

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Of all the worlds still to be explored, among the most mysterious may be closest to home. Indeed, it may be right between your ears.

22 Mar 2021

SARS-CoV-2 infection is circadian

An international team of researchers has found that angiotensin-converting enzyme 2 (ACE2) levels in lung cells vary over the day, affecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The virus entry and replication in the lung cells also have a rhythmic cycle, suggesting circadian processes can affect the virus's life cycle.

22 Mar 2021

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Although Tuberculosis, or TB, killed nearly as many people as COVID-19 (approx. 1.8 million) in 2020, it did not receive as much media and public attention.

22 Mar 2021

New treatment for late-stage neuroendocrine tumors found to be more effective and less toxic

A new treatment for late-stage neuroendocrine tumors (NETs) has been found to be more effective and have fewer side effects than the current standard of care, according to research published in the March issue of The Journal of Nuclear Medicine.

22 Mar 2021

Disease-driving B cells play a role in the development of NAFLD

New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) - the most common chronic liver condition in the U.S.

22 Mar 2021

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.

22 Mar 2021

Crisis standard of care guidelines may not exacerbate racial inequities

There are two simultaneously occurring pandemics in the U.S.: Racism and COVID-19. "These mutualistic pandemics have thrown into stark focus the separate and unequal systems through which people access health care," explained corresponding author Emily Cleveland Manchanda, MD, assistant professor of emergency medicine at Boston University School of Medicine.

22 Mar 2021

COVID-19 lockdown restrictions reduced light activity related to socializing and work

A study which looked at activity levels before and during the COVID-19 pandemic has found lockdown restrictions significantly reduced light activity associated with socializing and work.

22 Mar 2021

Medical Research News

Researchers use new approach to detect COVID-19 in wastewater

Researchers are working to speed up drug development to treat brain diseases

Ai helps identify critical interactions for SARS-CoV-2 spike protein binding to ACE2

Swiss research shows clusters of SARS-CoV-2 infection are rare within school classes

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

Simple SARS-CoV-2 mutations allow escape from the majority of polyclonal antibodies

Survey of smokers and vapers in the U.S. during COVID

Non-invasive scTS improves handgrip strength, motor control in people with complete tetraplegia

Study identifies metabolic processes associated with multiple, unrelated diseases

B.1.1.7 SARS-CoV-2 variant significantly more dangerous

Most cancer patients with COVID-19 produce antibodies at a rate comparable to general population

New research could help predict acute reactions to psychedelic drugs

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

SARS-CoV-2 infection is circadian

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

New treatment for late-stage neuroendocrine tumors found to be more effective and less toxic

Disease-driving B cells play a role in the development of NAFLD

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Crisis standard of care guidelines may not exacerbate racial inequities

COVID-19 lockdown restrictions reduced light activity related to socializing and work

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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