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What are the chief predictors of SARS-CoV-2 infection in children?

A new study seeks to explore the factors associated with the diagnosis in children. The ability to rapidly diagnose COVID-19 in this age group is essential not only for monitoring progressive disease in individual children, but to avert further transmission chains.

22 Mar 2021

United States ranks lowest in overall policies aimed at helping parents support children

National work-family policies that give lower-income families more time together while allowing them paid time off are more effective for children's psychological health than cash transfers, according to a study of developed nations led by Baylor University.

22 Mar 2021

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

To understand the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants (that are pathogenic) and other sarbecoviruses, a large team of researchers studied immunity by receptor-binding domain nanoparticle vaccines. They showed that a clinical-stage multivalent SARS-CoV-2 receptor-binding domain nanoparticle vaccine (SARS-CoV-2 RBD-NP) protected mice from the SARS-CoV-2-induced disease.

22 Mar 2021

Preventing future pandemics by ending the wildlife trade

In this News-Medical interview, we spoke to Professor Diana Bell about the illegal wildlife trade and how we could prevent future pandemics by stopping it.

22 Mar 2021

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

"The AMNOG procedure has passed its first practical test. It is practicable and can also be implemented in detail", emphasized IQWiG's Director Jürgen Windeler in October 2011, when the Institute had published its first early benefit assessment within the framework of the AM-NOG procedure (AMNOG = Act on the Reform of the Market for Medicinal Products).

22 Mar 2021

Novel technology may reveal the brain's mysteries

A team of scientists, led by researchers at Northwestern University, Shirley Ryan AbilityLab and the University of Illinois at Chicago (UIC), has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

22 Mar 2021

Researchers develop tools to detect chemical signals between the brain and immune system

If it seems like your stomach has a mind of its own, you're not wrong. University of Cincinnati assistant professor Ashley Ross says your body is full of neurons that regulate digestion, inflammation and a host of other biological processes.

22 Mar 2021

New study to identify prenatal and early childhood markers of high risk for food allergy and eczema

A study to identify prenatal and early childhood markers of high risk for food allergy and atopic dermatitis, or eczema, as well as biological pathways that lead to these conditions, has begun.

22 Mar 2021

Stress-free life may lead to lower cognitive function

Stress is a universal human experience that almost everyone deals with from time to time. But a new study found that not only do some people report feeling no stress at all, but that there may be downsides to not experiencing stress.

22 Mar 2021

New study shows how the immune system relates to cancer

Three University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the immune system relates to cancer.

22 Mar 2021

Asymptomatic individuals the biggest problem in COVID battle

The researchers noted in a study published in the journal Science, that asymptomatic cases are those that do not manifest symptoms for the infection duration. In contrast, presymptomatic cases develop symptoms later in the course of infection.

21 Mar 2021

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

Researchers at the University of Hong Kong found that Clofazimine, a lipophilic antimicrobial riminophenazine dye used in combination with agents like rifampicin and dapsone to treat leprosy, inhibits coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.

21 Mar 2021

People's politics, values shape COVID-19 risk perception and adoption of protective behaviors

People's politics and values are exerting a bigger influence on how much of a threat they feel from COVID-19 compared to objective indicators such as the number of confirmed cases.

21 Mar 2021

Hearing loss, other auditory problems strongly linked with Covid-19

Hearing loss and other auditory problems are strongly associated with Covid-19 according to a systematic review of research evidence led by University of Manchester and NIHR Manchester Biomedical Research Centre (BRC) scientists.

21 Mar 2021

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 kB viral genomes and subgenomic viral RNAs. However, how this is achieved is largely unknown.

21 Mar 2021

Consumption of processed meat associated with increased risk of dementia

Scientists from the University of Leeds's Nutritional Epidemiology Group used data from 500,000 people, discovering that consuming a 25g serving of processed meat a day, the equivalent to one rasher of bacon, is associated with a 44% increased risk of developing the disease.

21 Mar 2021

A review of the resilience of Chinese hospitals to the COVID-19 pandemic

A new review article, published on the medRxiv* preprint server, deals with several different aspects such as medical response capability, disaster health management, disaster preparedness, and health infrastructure safety, in China, by which they survived the COVID-19 crisis.

21 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

The United States is a few days from reaching President Biden's goal of vaccinating 100 million people 100 days since he took office. While the United States leads the world in both the number of COVID-19 cases at over 29.7 million and deaths reaching past 539,000, it has stepped up as a leader in vaccinating its population.

21 Mar 2021

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

The results of a double-blind, randomized, multisite placebo-controlled trial that was conducted in South Africa show that Oxford’s ChAdOx1 nCoV-19 (AZD1222) vaccine has no efficacy against the B.1.351 variant in preventing mild-to-moderate coronavirus disease 2019 (COVID-19), and shows reduced neutralization properties of developed antibodies. The findings are published in the New England Journal of Medicine.

21 Mar 2021

Medical Research News

What are the chief predictors of SARS-CoV-2 infection in children?

United States ranks lowest in overall policies aimed at helping parents support children

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

Preventing future pandemics by ending the wildlife trade

Study: Early benefit assessment of new drugs within the framework of AM-NOG procedure

Novel technology may reveal the brain's mysteries

Researchers develop tools to detect chemical signals between the brain and immune system

New study to identify prenatal and early childhood markers of high risk for food allergy and eczema

Stress-free life may lead to lower cognitive function

New study shows how the immune system relates to cancer

Asymptomatic individuals the biggest problem in COVID battle

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

People's politics, values shape COVID-19 risk perception and adoption of protective behaviors

Hearing loss, other auditory problems strongly linked with Covid-19

Blocking folate metabolism could reduce SARS-CoV-2 viral replication in infected cells

Consumption of processed meat associated with increased risk of dementia

A review of the resilience of Chinese hospitals to the COVID-19 pandemic

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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