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Maintaining a stable body weight does not reduce risk of death in colorectal cancer survivors

Colorectal cancer survivors who maintained a stable body weight but lost muscle and developed fatty deposits in their muscles faced a 40 percent higher risk of premature death than patients who avoided both health issues.

19 Mar 2021

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

19 Mar 2021

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Stroke patients treated via a mobile stroke unit (MSU) received clot-busting medications faster and more often - and recovered significantly better than patients who receive regular emergency care by standard ambulance.

19 Mar 2021

Researchers find stark disparities in COVID-19 outcomes

Researchers at Seattle's Institute for Systems Biology and their collaborators looked at the electronic health records of nearly 630,000 patients who were tested for SARS-CoV-2, and found stark disparities in COVID-19 outcomes -- odds of infection, hospitalization, and in-hospital mortality -- between White and non-White minority racial and ethnic groups.

19 Mar 2021

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes.

19 Mar 2021

Rare pulmonary disease discovered in rural Alberta

A rare pulmonary disease that is linked to bats has made Alberta home, according to new research led by provincial lab scientists.

19 Mar 2021

N-terminal domain antibodies play a key role in COVID immunity

Scientists are learning that a lesser-studied region on the pandemic coronavirus is recognized by COVID-19 infection-fighting antibodies. These antibodies were identified in blood samples from previously infected patients, and were found to potently prevent the virus from infecting cells.

19 Mar 2021

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

19 Mar 2021

Researchers use combined approach to estimate the timing of first SARS-CoV-2 case

Researchers who simulated early stages of the SARS-CoV-2 outbreak in Wuhan, China, conclude that the virus was likely circulating earlier than has been described, possibly even in mid-October 2019.

19 Mar 2021

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

Have you forgotten where you laid your keys? Ever wondered where you had parked your car? Or having trouble remembering the name of the new neighbor? Unfortunately, these things seem to get worse as one gets older.

19 Mar 2021

Study shows fragile countries had lower COVID-19 incidence, fatality rates

During a pandemic like COVID-19, vulnerable countries are traditionally the focus of global attention and concern. However, new research suggests that we need to rebuild our understanding.

19 Mar 2021

New discovery may prove vital to future research on medical cannabis

Medical cannabis is a subject of much debate. There is still a lot we do not know about cannabis, but researchers from the Department of Neuroscience at the Faculty of Health and Medical Sciences have made a new discovery that may prove vital to future research into and treatment with medical cannabis.

19 Mar 2021

New technology reveals neural origins of attention in babies

Anyone who has watched an infant's eyes follow a dangling trinket dancing in front of them knows that babies are capable of paying attention with laser focus.

19 Mar 2021

Study: Dopamine neurons respond to reward-predicting cues

Animals must make predictions about future rewards when making decisions during daily life. Specific reward-related patterns of neuronal activity are known to underlie such decisions.

19 Mar 2021

Chemical cocktail shows promise for producing muscle stem cells

A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.

19 Mar 2021

Specific neurons release dopamine to regulate pain differently in male and female mice

Males and females, generally speaking, experience and respond to pain differently, but scientists have yet to understand all the brain circuits involved in these differences.

19 Mar 2021

Study: Transcendental meditation can significantly reduce severity of PTSD symptoms

Veterans with PTSD who practiced the Transcendental Meditation technique showed significant reductions in PTSD symptom severity, according to a new study published today in Journal of Traumatic Stress.

19 Mar 2021

Study shows how ACE2 mutations influence SARS-CoV-2 spike binding in humans and animals

Researchers at the University of Wisconsin–Madison aimed to better understand how SARS-CoV-2 interacts with various mammalian angiotensin-converting enzyme 2 (ACE2) receptors. This way, they can identify the factors that influence intra- and cross-species virus transmission.

18 Mar 2021

Engineering immunogens to focus immune response to SARS-CoV-2

Researchers have designed constructs by adding more glycans and adding the receptor-binding motif from related sarbecoviruses to focus the immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding motif. Such immunogens could potentially also neutralize other variants and coronaviruses.

18 Mar 2021

Identifying druggable targets on an essential SARS-CoV-2 protein

In a research paper recently uploaded to the preprint server bioRxiv by Newman et al. (March 15th, 2021) the structure and role of one such protein: NSP13, is investigated, with two appealingly druggable targets being identified, possibly opening a new route towards a novel SARS-CoV-2 antiviral agent.

18 Mar 2021

Medical Research News

Maintaining a stable body weight does not reduce risk of death in colorectal cancer survivors

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Researchers find stark disparities in COVID-19 outcomes

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Rare pulmonary disease discovered in rural Alberta

N-terminal domain antibodies play a key role in COVID immunity

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

Researchers use combined approach to estimate the timing of first SARS-CoV-2 case

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

Study shows fragile countries had lower COVID-19 incidence, fatality rates

New discovery may prove vital to future research on medical cannabis

New technology reveals neural origins of attention in babies

Study: Dopamine neurons respond to reward-predicting cues

Chemical cocktail shows promise for producing muscle stem cells

Specific neurons release dopamine to regulate pain differently in male and female mice

Study: Transcendental meditation can significantly reduce severity of PTSD symptoms

Study shows how ACE2 mutations influence SARS-CoV-2 spike binding in humans and animals

Engineering immunogens to focus immune response to SARS-CoV-2

Identifying druggable targets on an essential SARS-CoV-2 protein

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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