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Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases, linked to the University of São Paulo in Brazil, discovered a novel path in the inflammatory process associated with the bone damage caused by rheumatoid arthritis.

18 Mar 2021

Immediate angiography for stroke patients linked to improved recovery, less disability

Immediate angiography, rather than the standard computed tomography (CT scan), reduced stroke treatment time and was linked to improved recovery, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2021.

18 Mar 2021

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease.

18 Mar 2021

Children exposed to disaster may forgo greater long-term reward for short-term pleasure

Living through a tragic event might make us more inclined to live for the moment, but not always in a good way. Research is looking into the psychological after-effects among children who survived the 2011 Great East Japan Earthquake, and a recent study may have made a connection: the children may forgo greater long-term reward for short-term pleasure.

18 Mar 2021

Undocumented pregnant women in Finland receive inadequate prenatal care, study shows

Undocumented women in Finland access pregnancy care later than others. Yet, screening of infectious diseases at the early stages of pregnancy would be particularly important to these women, a new study carried out in Helsinki, Finland, shows.

18 Mar 2021

Scientists explore structure of SARS-CoV-2 receptor-binding domain with G485R mutation

Researchers at the Bio21 Institute and Department of Biochemistry and Pharmacology, The University of Melbourne, studied the structure of a SARS-CoV-2 spike receptor-binding domain (RBD) with a G485R mutation. This mutation is a residue and not directly involved in interactions with the angiotensin-converting enzyme 2 (ACE2) residues but found in the Β1´/Β2' loop region.

18 Mar 2021

New study maps SARS-CoV-2 and host protein interactions in detail

A new study has developed a systemic map detailing the mechanistic interactions and disruptions between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its host cell.

18 Mar 2021

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

A recent study found that the Pfizer-BioNTech mRNA vaccine had limited efficacy in identifying mutated receptor-binding domains (RBDs) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein similar to the B.1.351 and P.1 variants.

18 Mar 2021

Study reveals unknown immune defense system that protects the lungs from viral infections

Researchers have uncovered a previously unknown arm of the immune defence system that protects the lung from lethal viral infections.

18 Mar 2021

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

Researchers based at the University of Oxford, UK, have shown that the P.1 Brazilian variant of SARS-CoV-2 is less resistant to natural or vaccine acquired antibody responses than the B.1.351, South African, variant, despite sharing convergent mutations.

18 Mar 2021

New Alzheimer's model may help test novel treatments

Our knowledge of Alzheimer's disease has grown rapidly in the past few decades but it has proven difficult to translate fundamental discoveries about the disease into new treatments.

18 Mar 2021

Study confirms that higher level of maternal folate increases the child’s birthweight

Imagine that you are going to conduct research on how different factors affect a child in the womb. Bad habits such as smoking, drinking alcohol or poor eating habits are factors that may affect the child.

18 Mar 2021

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

A new study discusses the question of how vaccine priority is affected by the possibility of vaccine escape.

18 Mar 2021

Could cinnamon modulate the immune response in severe COVID-19?

A new study describes the potential for two common plant products to make a difference in the management of severe COVID-19.

18 Mar 2021

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

Caused by SARS-CoV-2, the ongoing COVID-19 pandemic has led to over 121.2 million cases and over 2.6 million deaths worldwide. An interesting new study examines the potential antiviral activity of compounds present in the plant Artemisia annua L.

18 Mar 2021

New treatment for life-threatening lung condition receives NSF award

A Purdue University-affiliated startup developing a novel treatment for a life-threatening lung condition has won a $256,000 Small Business Technology Transfer Phase I award from the National Science Foundation.

18 Mar 2021

Scientists develop series of heart valve replacements to implant host cells into lambs

Combining tissue engineering and regenerative medicine, scientists have fabricated a series of heart valve replacements with the ability to incorporate host cells, enabling them to regenerate and grow over time.

18 Mar 2021

Researcher get federal grant to study how gut microbiota and inflammation promote metabolic syndrome

Dr. Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year federal grant just over $2 million to study how inflammation and altered gut microbiota, the microorganisms living in the intestine, influence the development of a group of diseases referred to as metabolic syndrome.

18 Mar 2021

New way to enhance treatment outcomes for breast cancer

Breast cancer is the most common cancer in women worldwide and the second most common cancer overall. Although it can now be treated with drugs, many of these drugs mysteriously stop working after some time, causing a relapse.

18 Mar 2021

Gene expression of viral entry factors may explain the differences of COVID-19 severity

A new study uncovers which cell types can be infected by SARS-CoV-2 due to their viral entry factors. The study also suggests that increased gene expression of these viral entry factors in some individuals partially explains the differences of COVID-19 severity reported in relation to age, gender and smoking status.

18 Mar 2021

Medical Research News

Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

Immediate angiography for stroke patients linked to improved recovery, less disability

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

Children exposed to disaster may forgo greater long-term reward for short-term pleasure

Undocumented pregnant women in Finland receive inadequate prenatal care, study shows

Scientists explore structure of SARS-CoV-2 receptor-binding domain with G485R mutation

New study maps SARS-CoV-2 and host protein interactions in detail

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

Study reveals unknown immune defense system that protects the lungs from viral infections

How resistant is the SARS-CoV-2 Brazilian variant to antibodies?

New Alzheimer's model may help test novel treatments

Study confirms that higher level of maternal folate increases the child’s birthweight

Can vaccine evading SARS-CoV-2 variants be restricted by prioritized vaccine rollout?

Could cinnamon modulate the immune response in severe COVID-19?

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

New treatment for life-threatening lung condition receives NSF award

Scientists develop series of heart valve replacements to implant host cells into lambs

Researcher get federal grant to study how gut microbiota and inflammation promote metabolic syndrome

New way to enhance treatment outcomes for breast cancer

Gene expression of viral entry factors may explain the differences of COVID-19 severity

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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