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Compromised immunity can allow SARS-CoV-2 to evade the immune system

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity--such as individuals receiving immune-suppressive drugs for autoimmune diseases--can become chronically infected.

17 Mar 2021

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

The severity of COVID-19 among the residents of long-term care facilities (LTCFs) has been reported to be disproportionately high. Specifically, individuals residing in skilled nursing facilities (SNFs) are found to be the most severely affected, both in terms of morbidity and mortality, and are, thereby, listed for early COVID-19 vaccination. In comparison to the general population, SNF residents are more vulnerable, with a weak immune system.

17 Mar 2021

AI-based technique determines cancer cells by their acidity

Healthy and cancer cells can look similar under a microscope. One way of differentiating them is by examining the level of acidity, or pH level, inside the cells.

17 Mar 2021

New technique could enable real-time distribution monitoring of ticks that carry Lyme disease

The findings of a recent analysis conducted by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that ecosystems suitable for harboring ticks that carry debilitating Lyme disease could be more widespread than previously thought in California, Oregon and Washington.

17 Mar 2021

Newly identified drugs can help treat oral and esophageal carcinomas

Discovering and treating tumors before they spread throughout the body is key for cancer patients to achieve positive outcomes. When tumor cells spread, which is known as metastasis, they can take over other organs and lead to death.

17 Mar 2021

Living with a COVID-19 case brings worse symptoms and stronger antibody response

This study suggests that high virus exposure levels contribute to greater disease severity and stronger antibody responses. The observations from this study are published on the medRxiv preprint server.

17 Mar 2021

People with high BMI may now receive their COVID-19 vaccine in California

Now, California state allows individuals with one of ten comorbidities to get their COVID-19 jabs. This comes after obesity being tagged as COVID-19 vaccine eligibility.

16 Mar 2021

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

As vaccine efforts against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease, roll out in various countries, Moderna ups the game by testing its next-generation COVID-19 vaccine.

16 Mar 2021

Salivary IgG to SARS-CoV-2 after mild COVID-19

A team of researchers based in Stockholm, Sweden, has demonstrated that individuals exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have antibodies for the disease up to nine months after acquiring the disease, even if they displayed only mild symptoms.

16 Mar 2021

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

Scientists in Colombia have identified a new highly divergent SARS-CoV-2 lineage with Spike substitutions L249S and E484K. These same mutations have convergently appeared in other mutant strains of the virus, most notably in variants of concern.

16 Mar 2021

SARS-CoV-2 can spread through cold-chain transport

In light of growing evidence, researchers say that SARS-CoV-2 virus transmission via contaminated surfaces, and in particular, frozen foods and products that are transported while keeping them at low temperatures, should be taken into account when devising prevention strategies.

16 Mar 2021

Study could lead to the development of novel treatments for drug-resistant cancers

ETC-159, a made-in-Singapore anti-cancer drug that is currently in early phase clinical trials for use in a subset of colorectal and gynecological cancers, could also prevent some tumors from resisting therapies by blocking a key DNA repair mechanism, researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research in Singapore reported in the journal EMBO Molecular Medicine.

16 Mar 2021

Novel protein construct prevents lethal COVID-19 in mice

Researchers in the United States have developed a novel protein that prevented lethal disease among mice infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

16 Mar 2021

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Parkinson's disease (PD) is a well-studied neurodegenerative disorder that affects between 7 and 10 million people worldwide.

16 Mar 2021

Study provides insight about development, mental health of underserved ethnically diverse children

A study in the Journal of the American Academy of Child and Adolescent Psychiatry, published by Elsevier, reports on the young adult assessment of the now 20-year longitudinal Boricua Youth Study (BYS), a large cohort that brings much needed insight about development and mental health of children from diverse ethnic background growing up in disadvantaged contexts.

16 Mar 2021

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Researchers in the United States have shown that saliva-based sampling could serve as an accurate and non-invasive alternative to blood sampling for monitoring people’s antibody responses following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or vaccination against the virus.

16 Mar 2021

Medical Research News

Compromised immunity can allow SARS-CoV-2 to evade the immune system

Evaluation of Pfizer-BioNTech COVID-19 vaccine among residents of two skilled nursing facilities

AI-based technique determines cancer cells by their acidity

New technique could enable real-time distribution monitoring of ticks that carry Lyme disease

Newly identified drugs can help treat oral and esophageal carcinomas

Living with a COVID-19 case brings worse symptoms and stronger antibody response

People with high BMI may now receive their COVID-19 vaccine in California

Testing for mRNA-1283, Moderna's next generation COVID-19 vaccine commences

Salivary IgG to SARS-CoV-2 after mild COVID-19

New Colombian SARS-CoV-2 lineage shares antibody-resistant mutations with other variants

SARS-CoV-2 can spread through cold-chain transport

Study could lead to the development of novel treatments for drug-resistant cancers

Novel protein construct prevents lethal COVID-19 in mice

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Study provides insight about development, mental health of underserved ethnically diverse children

Saliva-based testing as a method for monitoring population immunity to SARS-CoV-2 infection

Study: One in six men with advanced prostate cancer experiences reduced sense of smell and taste

Study: 94% of older adults prescribed fall-risk-increasing drugs

High levels of progesterone can reduce stress after concussion, speed recovery in females

Poor sleep may be a risk factor for developing complicated grief after a loss

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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