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Using virus-like particles to study SARS-CoV-2 assembly, budding, and entry

In a recent preprint paper published on the bioRxiv server, researchers from the Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, IN, discuss their efforts to assess the 4 SARS-CoV-2 structural proteins for their ability to produce VLPs from human cells to create a competent system for BSL-2 studies of SARS-CoV-2.

6 Oct 2020

Researchers examine COVID-19 pandemic’s effects on physical activity, sedentary behavior

Because of the COVID-19 pandemic, most universities across the United States transitioned from face-to-face classes to remote learning, closed campuses and sent students home this past spring.

6 Oct 2020

Self-isolation on arrival at airports dramatically improves detection of disease importation

Researchers from Public Health England have conducted a study showing that screening and quarantining travelers on arrival at airports significantly reduces the risk of disease importation during international outbreaks, compared with screening alone.

6 Oct 2020

Boys and girls who experience earlier puberty have increased risk of self-harm

Boys and girls who experience puberty earlier than their peers have an increased risk of self-harm in adolescence, a study funded by the National Institute for Health Research Bristol Biomedical Research Centre and published in the journal Epidemiology & Psychiatric Sciences today [Tuesday 6 October] has found.

6 Oct 2020

Liquid gel in COVID patients' lungs could be the key to new effective therapies

In some patients who died with severe COVID-19 and respiratory failure, a jelly was formed in the lungs. Researchers have now established what the active agent in the jelly is and thanks to that, this new discovery can now be the key to new effective therapies.

6 Oct 2020

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Elevated levels of a little-known lipoprotein in the blood that may put people at high risk of cardiovascular disease can be as accurately detected by genetic testing as by conventional laboratory measurement, researchers at Massachusetts General Hospital (MGH) have found.

6 Oct 2020

Low lymphocyte count before COVID-19 heightens death risk

Researchers at the University of Rochester Medical Center have conducted a study suggesting that having a low white blood cell count (lymphocytopenia) prior to exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be associated with an increased risk of dying from coronavirus disease 2019 (COVID-19).

6 Oct 2020

Insulin prices more than eight times higher in the U.S. than in other nations

Insulin prices are more than eight times higher in the United States than in 32 high-income comparison nations combined, according to a new RAND Corporation study.

6 Oct 2020

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease.

6 Oct 2020

Antigen testing detects SARS-CoV-2 better than PCR

A team of scientists from the United States demonstrates that rapid antigen tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more effective in determining the actual infection status in patients with coronavirus disease 2019 (COVID-19) than real-time polymerase chain reaction (RT PCR)-based tests.

6 Oct 2020

Optimized low‐dose drug combinations to effectively treat colorectal cancer

Chemotherapy-based cancer treatment has distressing side effects for patients and increases the risk of developing resistance to the treatment.

6 Oct 2020

Study reveals potential utility of artemisinin-based treatments against SARS-CoV-2

In a recent, methodologically robust bioRXiv preprint paper, researchers from Germany, Denmark and Hong Kong report in vitro efficacy of extracts from the sweet wormwood plant (Artemisia annua), but also artemisinin, artesunate and artemether derivatives against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Oct 2020

NIH awards $3.8 million to predict dementia in patients with Parkinson's disease

The National Institute of Neurological Disorders and Stroke at the National Institutes of Health has awarded a grant expected to total $3.8 million to Virendra Mishra, Ph.D., associate staff at Cleveland Clinic Lou Ruvo Center for Brain Health, to identify biomarkers - or disease indicators - to predict dementia in patients with Parkinson's disease.

6 Oct 2020

Tuned lighting helps improve sleep in nursing home residents, study finds

Nursing home residents tend to fall asleep at all hours of the day, and during the night, their sleep may be interrupted by periods of wakefulness.

6 Oct 2020

Study finds severe financial distress among breast cancer survivors

The effects of cancer treatment on a patient's body are easy to see, whether it is a lack of hair on their head, sores on their skin or a look of fatigue on their face.

6 Oct 2020

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

Only about one in every 170 children take them. But "orphan drugs" accounted for 1 in every 15 private insurance dollars spent on children's health care in the United States in 2018, according to a new study. That's up 65% from just five years before.

6 Oct 2020

UM associate professor wins multiple awards for ear, skin science

University of Montana scientist Monica Serban is on a research roll. In recent months the UM associate professor and her team have earned three awards totaling $3.9 million in funding to study preventing hearing loss among U.S. troops, combating ear infections and creating a synthetic skin product.

6 Oct 2020

Medical Research News

Using virus-like particles to study SARS-CoV-2 assembly, budding, and entry

Researchers examine COVID-19 pandemic’s effects on physical activity, sedentary behavior

Self-isolation on arrival at airports dramatically improves detection of disease importation

Boys and girls who experience earlier puberty have increased risk of self-harm

Liquid gel in COVID patients' lungs could be the key to new effective therapies

Genetic risk scoring of lipoprotein(a) can predict risk of atherosclerotic cardiovascular disease

Low lymphocyte count before COVID-19 heightens death risk

Insulin prices more than eight times higher in the U.S. than in other nations

Maternal sugary beverage intake during breastfeeding impacts cognitive development in children

Antigen testing detects SARS-CoV-2 better than PCR

Optimized low‐dose drug combinations to effectively treat colorectal cancer

Study reveals potential utility of artemisinin-based treatments against SARS-CoV-2

NIH awards $3.8 million to predict dementia in patients with Parkinson's disease

Tuned lighting helps improve sleep in nursing home residents, study finds

Study finds severe financial distress among breast cancer survivors

Study finds high out-of-pocket spending on orphan drugs for rare childhood diseases

UM associate professor wins multiple awards for ear, skin science

Dried plum diet prevents spinal cord injury‐related bone loss

Sperm mitochondrial DNA biomarkers may predict male reproductive health and pregnancy success

Dried blood spot samples accurately detect anti-SARS-CoV-2 S glycoprotein antibodies

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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