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Only 25% of SARS-CoV-2 infections are detected in the UK: Study

A new preprint research paper posted to the medRxiv server estimates the number of infections that are diagnosed from testing alone as being about a fourth of the total.

15 Feb 2021

Liquid biopsy can help gauge the effectiveness of therapy for colorectal cancer

A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor.

14 Feb 2021

Sounds appear to change the brain’s wiring patterns that process sound earlier than assumed

Scientists have yet to answer the age-old question of whether or how sound shapes the minds of fetuses in the womb, and expectant mothers often wonder about the benefits of such activities as playing music during pregnancy.

14 Feb 2021

Premature relaxation of restrictions following SARS-CoV-2 vaccination could lead to new mutations

A new preprint research paper posted to the medRxiv* server addresses the need to assess this risk by examining whether SARS-CoV-2 transmission can interact with vaccination rates to select vaccine-resistant strains. The study aims to provide data to shape effective countermeasures against the threat of viral resistance.

14 Feb 2021

Researchers identify prevalence, risk factors associated with sleep disorders in visually impaired athletes

Researchers from the University of Tsukuba have identified the prevalence and risk factors associated with sleep disorders in visually impaired athletes

14 Feb 2021

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

A new preprint research paper posted to the bioRxiv server demonstrates the potential of using the pre-existing protective responses to produce a broad-spectrum neutralizing response against not just SARS-CoV-2 but other future pathogens.

14 Feb 2021

New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.

14 Feb 2021

SARS-CoV-2's resistance to remdesivir in vitro

A new preprint research paper posted to the bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.

14 Feb 2021

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Researchers at Icahn School of Medicine at Mount Sinai in New York have provided evidence suggesting that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was infecting people in New York City (NYC) at least one month before the first case was officially documented in the city.

14 Feb 2021

Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Researchers from Cuba, China, and France have demonstrated the potential of coupling a viral antigen with the tetanus toxoid protein as a vaccination approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Feb 2021

Study reveals the effects of school closures on SARS-CoV-2 transmission among parents, teachers

Most countries introduced school closures during the spring of 2020 despite substantial uncertainty regarding the effectiveness in containing SARS-CoV-2.

13 Feb 2021

Interhemispheric connectivity important for integration of speech sound information, study shows

When we listen to speech sounds, the information that enters our left and right ear is not exactly the same.

13 Feb 2021

New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis.

13 Feb 2021

Poor and terminally ill Mexicans have less chance to get opioids intended for palliative care

If you're poor and terminally ill in southern Mexico, there's far less chance you'll get the painkillers you need for palliative care than your cousins in more prosperous regions, particularly those pharmacy-rich areas along Mexico-U.S. border, say UCLA researchers and colleagues who studied opioid dispensing levels across the country.

13 Feb 2021

Study characterizes cisplatin-induced hearing loss in pediatric cancer patients

Cisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases.

13 Feb 2021

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Every year around 20 Australian children die from the incurable brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years.

13 Feb 2021

Lund researchers discover how E. coli bacteria target and degrade MYC oncogene

Scientists at Lund University have discovered how E. coli bacteria target and degrade the well-known oncogene MYC, which is involved in many forms of cancer.

13 Feb 2021

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, these can secrete factors that turn macrophages -cells in the immune system- into dual action agents that contribute to the tumor progress and will protect it from immune body defenses: these become, thus, the tumor-associated macrophages (TAMs).

13 Feb 2021

New Cochrane Review: Hydroxychloroquine does not reduce deaths from COVID-19

Hydroxychloroquine does not reduce deaths from COVID-19, and probably does not reduce the number of people needing mechanical ventilation, state the authors of a new Cochrane Review.

13 Feb 2021

Study finds early risk factors for heightened anxiety in young adults during COVID-19

A new study has identified early risk factors that predicted heightened anxiety in young adults during the coronavirus (COVID-19) pandemic.

12 Feb 2021

Medical Research News

Only 25% of SARS-CoV-2 infections are detected in the UK: Study

Liquid biopsy can help gauge the effectiveness of therapy for colorectal cancer

Sounds appear to change the brain’s wiring patterns that process sound earlier than assumed

Premature relaxation of restrictions following SARS-CoV-2 vaccination could lead to new mutations

Researchers identify prevalence, risk factors associated with sleep disorders in visually impaired athletes

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

New mouse model of SARS-CoV-2 infection reflects features of human infection

SARS-CoV-2's resistance to remdesivir in vitro

SARS-CoV-2 was in NYC a good month before it was first identified, say researchers

Vaccine candidate containing tetanus toxoid potentially protective against SARS-CoV-2

Study reveals the effects of school closures on SARS-CoV-2 transmission among parents, teachers

Interhemispheric connectivity important for integration of speech sound information, study shows

New zebrafish model could help advance glioblastoma multiforme research

Poor and terminally ill Mexicans have less chance to get opioids intended for palliative care

Study characterizes cisplatin-induced hearing loss in pediatric cancer patients

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Lund researchers discover how E. coli bacteria target and degrade MYC oncogene

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

New Cochrane Review: Hydroxychloroquine does not reduce deaths from COVID-19

Study finds early risk factors for heightened anxiety in young adults during COVID-19

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

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