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N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Researchers from the Harbin Institute of Technology, China, modeled the complexes formed between the RBD and the human ACE2 and monoclonal antibodies.

27 Nov 2020

Urban women have higher risk of chronic diseases than rural dwellers

African women who live in cities are seven per cent more likely to have chronic diseases than rural dwellers.

27 Nov 2020

Researchers identify a neural pathway that links circadian clock, stress, and wakefulness

A Nagoya University-led research team in Japan has found a new neural pathway that links the circadian clock, stress, and wakefulness in mammals.

27 Nov 2020

Ipom-F inhibits SARS-CoV-2 infection in vitro

An international team of researchers showed the small molecule inhibitor, ipomoeassin F (Ipom-F), blocks the translocation/insertion of the three protein targets for SARS-CoV-2 infection.

27 Nov 2020

COVID-19 studies have neglected to focus on mucosal immunity, researchers argue

Researchers suggest that COVID-19 studies should focus on how mucous membranes in the mouth and nose develop immunity to the SARS-CoV-2 virus.

27 Nov 2020

Women at greater risk of heart disease than men

A new study has found that women are more likely than men to develop heart failure or die within five years after suffering a heart attack.

27 Nov 2020

Early life language exposure shapes infant brain function and development

The type and quantity of an infant’s language exposure relates to their brain function, according to new research published in JNeurosci.

27 Nov 2020

Lemann Foundation hails "spirit of co-operation' during wide-scale Brazilian clinical trial of Oxford/AstraZeneca vaccine

Denis Mizne, CEO of the Lemann Foundation, today hailed the “spirit of co-operation” during the wide-scale Brazilian clinical trials that helped deliver the Oxford/AstraZeneca COVID-19 vaccine, following the news that it is up to 90% per cent effective after passing phase-3 global trials.

27 Nov 2020

New clinical trial to compare the impact of anesthesia methods on post-surgery outcomes

A new clinical trial will compare two types of anesthetic to determine how soon after surgery they allow patients to return home.

27 Nov 2020

Monash project aims to address post-pandemic mental health challenges of teenagers

A Monash University project will look at reducing the long-term risk of adolescent mental health problems by enhancing parents’ ability to support their children throughout the pandemic.

27 Nov 2020

‘Molecular clock’ blood test could help identify actively growing tumors in metastatic breast cancer

A blood test to watch breast cancer’s ‘molecular clock’ could help track the growth of multiple tumors around the body and monitor how they are responding to treatment, new research suggests.

27 Nov 2020

Coeliac UK and Innovate UK announce winner of £180K from their 2019 research call

Coeliac UK, the UK charity for people who need to live gluten free, along with Innovate UK, the UK’s innovation agency, announces joint funding of £180K from their 2019 research call, has been awarded to Lyzeum Ltd.

27 Nov 2020

Immunonutrition may improve COVID-19 patients' recovery

Researchers duo Emma Derbyshire and Joanne Delange from the Nutritional Insight, Surrey, United Kingdom, explore the role of immunonutrition – nutrition that boosts or influences the immune system for those over 65 years of age in COVID-19. Their study titled, “COVID-19: is there a role for immunonutrition, particularly in the over 65s?,” was released in the latest issue of the BMJ Nutrition, Prevention and Health.

26 Nov 2020

Body mass index and severe COVID-19

French researchers led by first author Abdallah Al-Salameh from the Department of Endocrinology, Diabetes Mellitus and Nutrition, Amiens University Hospital, Amiens, France, have published findings of their study titled, “The association between body mass index class and coronavirus disease 2019 outcomes,” in the latest issue of the International Journal of Obesity.

26 Nov 2020

Novel early-warning framework for evaluating control and elimination of SARS-CoV-2 in NZ

Researchers from the Imperial College London and the University of Oxford recently proposed a new framework for de-noising inter-wave data, showing how timely introduction of NPIs in New Zealand achieved local epidemic elimination and avoided dangerous resurgence of infection.

26 Nov 2020

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

In a preprint paper published on the medRxiv server, a team of researchers from various institutions in South Africa, the UK, and Europe discuss how they determined the impact of HIV on the COVID-19 immune response in KwaZulu-Natal, South Africa, which is an area with very high HIV prevalence.

26 Nov 2020

Creating an affordable food source to tackle malnutrition in Zimbabwe

Scientists at the University of Sheffield are helping to tackle malnutrition in Zimbabwe through the mass development of an insect-based porridge.

26 Nov 2020

Novel cannabis plant extracts could protect against COVID-19

Researchers in Canada have conducted a study suggesting that novel Cannabis sativa extracts may decrease levels of the host cell receptor that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses to gain viral entry to target tissues.

26 Nov 2020

Combining cell engineering with machine learning to design living medicines for cancer

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.

26 Nov 2020

Transgenic mouse model could recapitulate severe COVID-19 in humans

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe disease course in humans.

26 Nov 2020

Medical Research News

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Urban women have higher risk of chronic diseases than rural dwellers

Researchers identify a neural pathway that links circadian clock, stress, and wakefulness

Ipom-F inhibits SARS-CoV-2 infection in vitro

COVID-19 studies have neglected to focus on mucosal immunity, researchers argue

Women at greater risk of heart disease than men

Early life language exposure shapes infant brain function and development

Lemann Foundation hails "spirit of co-operation' during wide-scale Brazilian clinical trial of Oxford/AstraZeneca vaccine

New clinical trial to compare the impact of anesthesia methods on post-surgery outcomes

Monash project aims to address post-pandemic mental health challenges of teenagers

‘Molecular clock’ blood test could help identify actively growing tumors in metastatic breast cancer

Coeliac UK and Innovate UK announce winner of £180K from their 2019 research call

Immunonutrition may improve COVID-19 patients' recovery

Body mass index and severe COVID-19

Novel early-warning framework for evaluating control and elimination of SARS-CoV-2 in NZ

HIV alters SARS-CoV-2 immune response without affecting COVID-19 symptoms or outcomes

Creating an affordable food source to tackle malnutrition in Zimbabwe

Novel cannabis plant extracts could protect against COVID-19

Combining cell engineering with machine learning to design living medicines for cancer

Transgenic mouse model could recapitulate severe COVID-19 in humans

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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