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New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

People taking placebo pills and statins experienced similar side effects, shows study

People taking dummy pills and statins experienced similar side effects in a new study.

15 Nov 2020

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

De'Broski Herbert has a philosophy that's guided his career researching helminths, or parasitic worms, and their interaction with their hosts' immune systems: "Follow the worm."

15 Nov 2020

New cancer study may result in more effective treatments

For decades, scientists and doctors have been searching for a cure for cancer. Now, researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have taken a significant step forward with a new concept that could ultimately result in more effective treatments.

15 Nov 2020

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

A team of researchers from the Northern Arizona University evaluated a new PARP inhibitor, stenoparib, which has recently advanced to Stage II of clinical trials to treat ovarian cancer. Their study, an initial report on in vitro stenoparib activity against human coronaviruses such as SARS-CoV-2, has been published on the preprint server bioRxiv*.

15 Nov 2020

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

The paper, put together by a team of scientists based in the United Kingdom and Italy, also underscored the need for healthcare policies to account for the very real possibility of inadequate protective personal equipment (PPE), staff and hospital capacity, aggravated by the increased number of pediatric infections.

15 Nov 2020

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

A new paper published in the journal Science of the Total Environment on November 10, 2020, discusses the reality of the virus’s wastewater transmission. Overall, the researchers found that wastewater transmission would have a disproportionate impact on countries with low development indices.

15 Nov 2020

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

To try and shed more light on SARS-CoV-2’s transmission, a research group based in Italy examined a COVID-19 isolation ward in a Milan hospital to evaluate the level of contamination present in the air and on surfaces with SARS-CoV-2 RNA (the virus’s genetic material).

15 Nov 2020

Multi-faceted COVID-19 strategy can prevent infections, save lives in resource-challenged countries

A public health strategy that combines contact tracing and community-based screening with isolation and quarantine centers can substantially reduce infections, hospitalizations and deaths from COVID-19 while being cost-effective in low-and-middle-income countries like South Africa, a study by Massachusetts General Hospital has found.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

A University of Cincinnati immunologist is recommending that individuals with contact dermatitis choose facial masks made without elastic or rubber that allow them to stay safe in the midst of COVID-19 while avoiding possible allergic reactions.

15 Nov 2020

New screening strategy can help identify individuals with higher probability of developing heart disease

More than 40% of middle-aged adults have silent coronary artery disease. Researchers have developed a new screening questionnaire to help identify individuals at the highest risk for coronary artery disease, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Researchers in Sweden and China have presented a new methodology for predicting mutation “hotspot” sites within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Researchers identify prognostic markers that could guide COVID-19 management

A team of researchers in Europe has created a comprehensive data resource to help improve understanding of how coronavirus disease 2019 (COVID-19) progresses and how biomarkers could be used to guide treatment approaches and disease monitoring.

15 Nov 2020

Fish oil and vitamin D supplements do not decrease nor increase the risk of atrial fibrillation

Taking omega-3 fatty acids and vitamin D3 supplements does not neither increase nor decrease the risk of developing atrial fibrillation, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Patients who were hospitalized with acute heart failure and had iron deficiency were less likely to return to the hospital if given intravenous iron replacement, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Promising MS drug may make the debilitating disease worse

A drug that has shown promise for treating multiple sclerosis may actually make the debilitating disease worse, new research from the University of Virginia School of Medicine suggests.

15 Nov 2020

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19, from small samples of saliva, according to a study led by Bloomberg School researchers.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

The study, which appeared in the Journal of Taibah University Medical Sciences, shows that the SARS-CoV-2 may behave akin to the CNS pathogenic mechanism of JEV and HIV during the early stages of infection.

15 Nov 2020

Medical Research News

New data highlights safety concerns on rAAV vectors used in gene therapy

People taking placebo pills and statins experienced similar side effects, shows study

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

New cancer study may result in more effective treatments

PARP inhibitor, stenoparib inhibits pre- and post-entry processes of SARS-CoV-2 in vitro

Strategizing pediatric healthcare preparedness for the second wave of the COVID-19 pandemic

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

Multi-faceted COVID-19 strategy can prevent infections, save lives in resource-challenged countries

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Elastic-free facial masks could benefit individuals with contact dermatitis during COVID-19

New screening strategy can help identify individuals with higher probability of developing heart disease

New methodology predicts mutation hotspots in SARS-CoV-2 virus

Researchers identify prognostic markers that could guide COVID-19 management

Fish oil and vitamin D supplements do not decrease nor increase the risk of atrial fibrillation

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Promising MS drug may make the debilitating disease worse

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Dopamine-release mechanisms in the brain may play a major role in SARS-CoV-2 infection

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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