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SARS-CoV-2 with D614G mutation is prevalent in central India

A team of scientists at the Defence Research and Development Establishment, India, reveals that there are multiple viral introduction events in central India, and SARS-CoV-2 with D614G mutation is the prevalently circulating strain.

16 Sep 2020

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

In a promising study by US researchers, the receptor-binding domain (RBD) and stabilized spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were displayed on nanoparticles as vaccine antigens and elicited potent immune responses.

16 Sep 2020

Low birth weight appears to increase risk of severe COVID-19 in adults

Researchers in Barcelona, Spain have conducted a study showing that low birth weight seems to be an independent risk factor for severe illness among non-elderly adults with coronavirus disease 2019 (COVID-19).

16 Sep 2020

Candidate monoclonal antibody shows hope as COVID-19 treatment

Researchers in the United States have described the effectiveness of a candidate monoclonal antibody currently being evaluated in a Phase 1 trial as a therapy for coronavirus disease 2019 (COVID-19) and its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Sep 2020

Non-invasive test of brain function could predict treatment response in depressed teen girls

The risk of developing major depressive disorder (MDD) surges during adolescence-particularly for girls. Cognitive behavioral therapy (CBT) can be an effective treatment, but only about half of girls diagnosed with depression show significant improvement.

16 Sep 2020

Physical diseases increase risk of being hospitalized with depression

Patients with a first-time depression diagnosis have an increased risk of the disease worsening and requiring hospitalization, if they have previously been treated for a physical disease at a hospital.

16 Sep 2020

Study uncovers new markers present on melanoma tumors

A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.

16 Sep 2020

Women are more depressive in societies with low gender equality rankings

Overall, scientists from 24 countries and regions contributed, including the United Kingdom, Saudi Arabia, the Netherlands, the United States, Greece, Germany, Brazil, Pakistan, Malaysia, Australia, Argentina, Georgia, Romania, Armenia, Chile, China (with Hong Kong as a separate participant), Turkey, Italy, and Mexico.

16 Sep 2020

Carotid artery calcification seen in radiographs linked with coronary artery disease, oral infections

The calcification of the carotid artery is a sign of advanced arteriosclerosis, which may be associated with chronic coronary artery disease (CAD) and can lead to death. Such calcification can be seen in regular oral panoramic radiography.

16 Sep 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

Mathematical model to show how to prevent fistulas in women during childbirth

It is better to invest in measures that make it easier for women to visit a doctor during pregnancy than measures to repair birth injuries.

16 Sep 2020

Study investigates the outcomes of heart transplants from severely obese donors

Heart transplant patients who received hearts from severely obese donors had similar short-term outcomes and long-term survival as patients who received hearts from non-obese donors, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.

16 Sep 2020

Better heart health linked to lower risk of developing hypertension in middle-aged adults

Better heart health, as measured by the American Heart Association's Life's Simple 7 (LS7) scale, was associated with a significantly lower risk of developing high blood pressure (also known as hypertension) in middle-aged, Black and white adults, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

16 Sep 2020

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Now, a new study by researchers from Pfizer, University of Arizona, Purdue University, The Scripps Research Institute, and UC San Diego School of Medicine and published on the preprint server bioRxiv in September 2020 reports that an enzyme inhibitor may act in synergism with the approved antiviral remdesivir to suppress viral replication in COVID-19.

16 Sep 2020

Critical insights into COVID-19 exposure for healthcare workers

A recent Northwestern University Feinberg School of Medicine study published in the preprint server medRxiv in September 2020 shows that the use of standard guidelines of infection control, including personal protective equipment (PPE), helps to prevent the undue risk of infection among HCWs as well.

16 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Researchers and clinicians share findings on ovarian cancer

After nearly four years of work, a group of researchers and clinicians from the University of Colorado (CU) published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response.

16 Sep 2020

Heparan sulfate aids COVID-19 virus to penetrate human lung cells

A molecule known as ACE2 sits like a doorknob on the outer surfaces of the cells that line the lungs. Since January 2020, researchers have known that SARS-CoV-2, the novel coronavirus that causes COVID-19, primarily uses ACE2 to enter these cells and establish respiratory infections.

16 Sep 2020

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Initial findings reported by the Arizona COVID-19 Genomics Union (ACGU) suggest that following Arizona's first reported case of COVID-19 in late January, the state experienced no cases that went undetected and was COVID-free until at least 11 distinct incursions occurred between mid-February and early April.

16 Sep 2020

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions.

16 Sep 2020

Medical Research News

SARS-CoV-2 with D614G mutation is prevalent in central India

Self-assembling nanoparticles as a way towards next-generation COVID-19 vaccines

Low birth weight appears to increase risk of severe COVID-19 in adults

Candidate monoclonal antibody shows hope as COVID-19 treatment

Non-invasive test of brain function could predict treatment response in depressed teen girls

Physical diseases increase risk of being hospitalized with depression

Study uncovers new markers present on melanoma tumors

Women are more depressive in societies with low gender equality rankings

Carotid artery calcification seen in radiographs linked with coronary artery disease, oral infections

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Mathematical model to show how to prevent fistulas in women during childbirth

Study investigates the outcomes of heart transplants from severely obese donors

Better heart health linked to lower risk of developing hypertension in middle-aged adults

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Critical insights into COVID-19 exposure for healthcare workers

Study provides valuable insights on effects of APOE gene on health and disease

Researchers and clinicians share findings on ovarian cancer

Heparan sulfate aids COVID-19 virus to penetrate human lung cells

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Gut Microbiome Health Index distinguishes between healthy and diseased microbiome

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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