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New modeling study shows increased future demand for cancer surgery

Public health researchers, led by UNSW Sydney, have estimated the number of cancer cases requiring surgery globally each year, predicting the number will rise from 9.1 million to 13.8 million from 2018 to 2040 - an increase of 52 per cent or 4.7 million cases.

25 Jan 2021

Greater sports participation linked with better academic performance in Indigenous children

Greater sports participation among Aboriginal and Torres Strait Islander children is linked with better academic performance, according to new research from the University of South Australia.

25 Jan 2021

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

The cover for issue 2 of Oncotarget features Figure 4, "Combination therapy TA99/ICB reduced the lung tumor burden in the B16 model of metastases," published in "Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma" by Pérez-Lorenzo, et al. which reported that here, the authors showed that removing immune suppression and enhancing stimulatory signals increased the anti-tumor activity of unmodified TA99 antibodies with a significant reduction of growth of solid tumors and lung metastases in mouse models of melanoma.

25 Jan 2021

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

The cover for issue 52 of Oncotarget features Figure 1, "Volcano plots of DNA methylation in tumor tissues compared with nontumor tissue," published in "Reduction of T-Box 15 gene expression in tumor tissue is a prognostic biomarker for patients with hepatocellular carcinoma" by Morine, et al. which reported that the authors conducted a genome-wide analysis of DNA methylation of the tumor and non-tumor tissue of 15 patients with Hepatocellular carcinoma (HCC), and revealed TBX15 was the most hypermethylated gene of the tumor.

25 Jan 2021

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment.

25 Jan 2021

Study identifies early warnings of COVID-19 outbreak on Twitter posts

Even before public announcements of the first cases of COVID-19 in Europe were made, at the end of January 2020, signals that something strange was happening were already circulating on social media.

25 Jan 2021

Promising nanobodies against COVID-19 produced by llamas

News-Medical speaks to Dr. David Brody about his latest research that involved discovering nanobodies produced by llamas that could help combat coronavirus.

25 Jan 2021

Scientists call for strict control measures to reduce the spread of new COVID-19 variants

A group of scientists is calling on governments to consider the continued use of strict control measures as the only way to reduce the evolution and spread of new COVID-19 variants.

25 Jan 2021

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

The Institute for Research in Biomedicine (IRB; Bellinzona, Switzerland), affiliated to the Università della Svizzera italiana (USI) developed a second-generation 'double antibody' that protects from SARS-CoV-2, the virus causing COVID-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy.

24 Jan 2021

Study looks at anxiety of HCW during the COVID-19 pandemic

The study reveals that healthcare workers from Saudi Arabia suffer from a high level of anxiety due to a higher risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server.

24 Jan 2021

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

A team of international scientists has demonstrated that therapeutic inhibition of a transcriptional regulator BRD2, required for the endogenous expression of angiotensin-converting enzyme 2 (ACE2), can potentially suppress severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv* preprint server.

24 Jan 2021

Experts advise disaggregating data on COVID-19 patients by sex

Researchers at Yale University School of Medicine have highlighted the importance of ensuring studies of patients with coronavirus disease 2019 (COVID-19) report data in a sex-disaggregated manner.

24 Jan 2021

Researchers show how to estimate long-term efficacy of COVID-19 vaccines

Researchers at the University of North Carolina and the Fred Hutchinson Cancer Research Center in Washington have developed a way to evaluate vaccines' long-term efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

24 Jan 2021

New maintenance treatment for AML shows strong benefit for patients

Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3 clinical trial for which Weill Cornell Medicine and NewYork-Presbyterian are trial sites.

22 Jan 2021

Study examines risk factors for developing ME/CFS in college students after infectious mononucleosis

Many college students fully recover from infectious mononucleosis (which is almost always caused by Epstein-Barr virus) within 1-6 weeks, but some go on to develop chronic fatigue syndrome, also called myalgic encephalomyelitis (ME/CFS).

22 Jan 2021

George Mason researchers investigating COVID-19 therapies

Yuntao Wu, Professor, Molecular and Microbiology, and Ramin Hakami, Associate Professor, School of Systems Biology, are conducting studies of COVID-19 therapies.

22 Jan 2021

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer.

22 Jan 2021

Study shows disproportionate impact of COVID-19 on Black and Asian populations

Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust.

22 Jan 2021

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

Dramatic changes were seen in the delivery of radiotherapy treatments for cancer during the first wave of the coronavirus pandemic in England.

22 Jan 2021

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'.

22 Jan 2021

Medical Research News

New modeling study shows increased future demand for cancer surgery

Greater sports participation linked with better academic performance in Indigenous children

Combining anti-tumor antibodies with standard-of-care improves therapeutic outcomes in cancer

Reduced expression of TBX15 in tumor tissue represents a prognostic biomarker for HCC patients

Socioeconomic conditions linked to high viral load despite treatment for HIV patients in Ethiopia

Study identifies early warnings of COVID-19 outbreak on Twitter posts

Promising nanobodies against COVID-19 produced by llamas

Scientists call for strict control measures to reduce the spread of new COVID-19 variants

Second-generation double antibody protects from SARS-CoV-2 and its tested variants

Study looks at anxiety of HCW during the COVID-19 pandemic

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

Experts advise disaggregating data on COVID-19 patients by sex

Researchers show how to estimate long-term efficacy of COVID-19 vaccines

New maintenance treatment for AML shows strong benefit for patients

Study examines risk factors for developing ME/CFS in college students after infectious mononucleosis

George Mason researchers investigating COVID-19 therapies

Researchers identify protein that may represent a safer treatment target for pancreatic cancer

Study shows disproportionate impact of COVID-19 on Black and Asian populations

Dramatic changes seen in delivery of radiotherapy treatments during coronavirus pandemic

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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