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Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Clostridium difficile infection (CDI) is inflammation of the colon caused by a bacteria called clostridium difficile and is the most common cause of infectious diarrhea in hospitalized patients.

8 Dec 2020

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles.

8 Dec 2020

Economic implications due to COVID-19 can have a devastating effect on children

A team of UTSA researchers has discovered that economic implications because of COVID-19 can have a devastating ripple effect on children.

8 Dec 2020

Study explores link between negative career thoughts and parental relationships in adolescents with ADHD

A new study published in The Career Development Quarterly looked for potential links between negative or dysfunctional career thoughts and the quality of parental relationships in high school students with attention-deficit/hyperactivity disorder (ADHD).

8 Dec 2020

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units.

8 Dec 2020

Researchers address variability of disease severity in respiratory tract infections

Is it possible to predict the course of a viral respiratory tract infection - for instance one caused by a coronavirus - based on individual patient characteristics? This question will be addressed by Dr. Victor Corman and his junior research group at Charité - Universitätsmedizin Berlin.

8 Dec 2020

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

The omega-3 fatty acids EPA and DHA work differently against chronic inflammation, according to the results of a small randomized study, suggesting each has its own important role to play in regulating the immune system.

8 Dec 2020

Higher degrees of necrosis are inked to poor survival in brain cancer patients

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.

8 Dec 2020

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Novel menin-KMT2A inhibitor appears to be safe and well-tolerated. FLT3 inhibitor plus low-dose chemotherapy shows promising efficacy and safety. Results represent encouraging news on hard-to-treat AML subtypes.

7 Dec 2020

Studies show IgA antibodies dominate early response to SARS-CoV-2 virus

A new study of more than 150 COVID-19 patients shows that IgA antibodies dominate the early response to the SARS-CoV-2 virus, coming on more quickly and strongly than IgG and IgM antibodies. This is a somewhat unexpected result, as IgM antibodies are usually the immune system's first responders.

7 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Roswell Park Comprehensive Cancer Center's Francisco J. Hernandez-Ilizaliturri, MD, along with a team of researchers from other institutions, has been investigating a novel therapy for patients with relapsed or refractory B-cell non-Hodgkin lymphoma.

7 Dec 2020

Antibody responses to SARS-CoV-2 virus disappear quickly during convalescence, indicates study

A new 5-month longitudinal analysis of 254 COVID-19 patients who displayed a wide range of disease severity - from asymptomatic to deadly illness - suggests that IgA and IgM antibodies to the SARS-CoV-2 virus disappear quickly during convalescence.

7 Dec 2020

Patients with atopic dermatitis more likely to have autoimmune diseases

In a recent study published in the British Journal of Dermatology, individuals with atopic dermatitis, or eczema, were more likely to also have various autoimmune diseases, especially those involving the skin, the gastrointestinal tract, or the connective tissue.

7 Dec 2020

Study: Caplacizumab not cost effective for treating thrombotic thrombocytopenic purpura

In a new study by Yale Cancer Center researchers, the drug caplacizumab is shown not to be cost-effective in treating thrombotic thrombocytopenic purpura (TTP) when added to the standard-of-care.

7 Dec 2020

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.

7 Dec 2020

Researchers develop new approach for COVID-19 testing

Researchers from UC San Francisco and the Chan Zuckerberg Biohub have developed a new approach for COVID-19 testing that detects a distinct pattern of immune gene expression in infected individuals.

7 Dec 2020

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

A drug currently prescribed to treat a rare enzyme deficiency can help cells clear the herpes simplex 1 and herpes simplex 2 viruses, according to a new study published in the journal Science Advances.

7 Dec 2020

Adolescent competitive sport participation linked to better fitness at midlife in women

Females who participate in competitive sport during adolescence have better fitness at midlife than do females with no competitive sport background in adolescence, reveals a study conducted at the University of Jyväskylä.

7 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

Medical Research News

Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Economic implications due to COVID-19 can have a devastating effect on children

Study explores link between negative career thoughts and parental relationships in adolescents with ADHD

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Researchers address variability of disease severity in respiratory tract infections

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Studies show IgA antibodies dominate early response to SARS-CoV-2 virus

Study highlights previously unknown mechanisms involved in myeloma resistance

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Antibody responses to SARS-CoV-2 virus disappear quickly during convalescence, indicates study

Patients with atopic dermatitis more likely to have autoimmune diseases

Study: Caplacizumab not cost effective for treating thrombotic thrombocytopenic purpura

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Researchers develop new approach for COVID-19 testing

Drug prescribed for rare enzyme deficiency shows promise to treat herpes viruses

Adolescent competitive sport participation linked to better fitness at midlife in women

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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