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Optimizing allocation of future COVID-19 vaccine can double effectiveness

In anticipation of coronavirus disease (COVID-19) vaccine deployment, the Australian and US researchers utilized an age-structured mathematical model to appraise the potential benefits of optimizing age-specific dose allocation for suppressing SARS-CoV-2 transmission – and reaffirmed the notion that vaccination alone may be inadequate to achieve herd immunity in some settings. The study is currently available on the medRxiv* preprint server.

12 Oct 2020

Scientists develop new type of precise therapeutic vaccine against leukemia

Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.

12 Oct 2020

Nasal spray COVID-19 vaccine shows promising results in mice

With promising vaccines comes a new candidate that has shown potent pre-clinical immune responses. The vaccine, developed by scientists at the University of Alabama at Birmingham (UAB), induced a potent T-cell response at the mucus layer of the lungs, including killer CD8+ T-cells, which can recognize and kill virally infected cells.

12 Oct 2020

SARS-CoV-2 can survive for 4 weeks on glass, money and metal

Published in the Virology Journal, the study shows that the virus can stay infectious for more extended periods on surfaces such as phone screens, stainless steel, and banknotes than previously thought.

12 Oct 2020

Dopamine and serotonin play role in perception and decision-making

Scientists at Wake Forest School of Medicine have recorded real time changes in dopamine and serotonin levels in the human brain that are involved with perception and decision-making.

12 Oct 2020

UniSA researchers are one step closer to finding new biomarker for osteoarthritis

University of South Australia researchers are a step closer to finding a new biomarker for osteoarthritis, a painful condition which affects more than two million Australians and costs the country an estimated $23 billion a year.

12 Oct 2020

People with pandemic-related stress show least engagement at work

As COVID-19 cases surged this spring, the pandemic led some people more than others to ponder their own mortality. A new study in China and the United States suggests that these people were the ones who showed the highest levels of stress and the least engagement at work.

12 Oct 2020

Researchers develop online game to tackle the deluge of coronavirus misinformation

A new online game that puts players in the shoes of a purveyor of fake pandemic news is the latest tactic in efforts to tackle the deluge of coronavirus misinformation costing lives across the world.

12 Oct 2020

HIV self-tests improve "door-to-door" testing campaigns

Despite significant progress in prevention and therapy, millions of people still get infected with HIV every year.

12 Oct 2020

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Volume 11, Issue 26 of Oncotarget reported that in this study the authors studied the differences in mi RNA expression between sporadic and FAP-associated Desmoid tumors using microarray confirmed by quantitative PCR.

12 Oct 2020

Women experience employment disruption following cancer diagnosis

Cancer and its treatment can impact an individual's ability to work, and employment disruptions can lead to financial hardships. A new study indicates that women who were diagnosed with cancer as adolescents or young adults can be especially vulnerable to these effects.

12 Oct 2020

Study highlights ongoing disparity in inflammatory breast cancer

Women with inflammatory breast cancer - a rare, highly aggressive form of the disease - are living about twice as long after diagnosis than their counterparts in the mid-to-late 1970s, according to a new University of Michigan Rogel Cancer Center study.

12 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Combination of biology and lifestyle increases COVID-19 mortality in men

Being a man, having a lower income, having a lower level of education, not being married, and being born abroad in low- or middle-income countries - these are factors that, independent of one another, are related to an elevated risk of dying from COVID-19 in Sweden.

12 Oct 2020

Scientists 3D print special fluid channels that could be used for medical testing

In a groundbreaking new study, researchers at the University of Minnesota, in collaboration with the U.S. Army Combat Capabilities Development Command Soldier Center, have 3D printed unique fluid channels at the micron scale that could automate production of diagnostics, sensors, and assays used for a variety of medical tests and other applications.

12 Oct 2020

Study shows evidence-based patient education is important in tinnitus

About 50 million people in the United States suffer with tinnitus, a condition in which people perceive sounds such as ringing or buzzing in their ears or head. It is the number one service-related disability among U.S. veterans.

12 Oct 2020

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

Study explains why milk is an effective way to quench the burn of spicy food

Maybe you've heard that milk is the perfect way to extinguish that spicy food burn. Why is milk so effective? And what if you can't drink milk?

12 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Peer reviewers flag misleading studies on COVID-19

The preprints selected for review in Rapid Reviews: COVID-19 (RR:C19), an open-access overlay journal published by the MIT Press, cover a wide range of subjects, with peer reviewers finding a study that higher levels of cytokines IL-6 and IL-10 are associated with increased severity of COVID-19 is particularly noteworthy and could be useful in clinical care.

12 Oct 2020