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Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%.

21 Sep 2020

A cost-effective scalable production of SARS-CoV-2 RBD in yeast

A new study by the Argentinian AntiCovid Consortium and published in the preprint server bioRxiv* in September 2020 reports on the successful characterization of the conformation and stability of the SARS-CoV-2 spike protein receptor-binding domain (RBD) in two different cell systems. This may help to accelerate the development of vaccines and neutralizing antibodies.

21 Sep 2020

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

According to updated findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery continues to significantly improve disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) gene mutations.

21 Sep 2020

Machine-learning algorithm can detect early, subtle signs of osteoarthritis

Researchers at the University of Pittsburgh School of Medicine and Carnegie Mellon University College of Engineering have created a machine-learning algorithm that can detect subtle signs of osteoarthritis- too abstract to register in the eye of a trained radiologist- on an MRI scan taken years before symptoms even begin.

21 Sep 2020

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

A recent study reveals how the non-structural protein 1 (NSP1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a crucial role in inhibiting the host cell protein synthesis but simultaneously facilitating the viral protein synthesis.

21 Sep 2020

CABI scientists highlight COVID-19 implications on food security in Kenya and Uganda

CABI scientists have conducted new research highlighting the impact of COVID-19 pandemic on food security in Kenya and Uganda with more than two-thirds of those surveyed having experienced economic hardship due to the pandemic.

21 Sep 2020

Oncology nurses should be routinely tested for SARS-CoV-2, warn researchers

Researchers from the NHS Foundation Trust, University of Cambridge and Cambridge Clinical Laboratories have warned that until a vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) becomes available, antigen and antibody testing should be carried out among oncology nurses as part of routine patient care.

21 Sep 2020

Study finds how different strategies may impact clinical trial enrollment

As electronic medical records (EMR) become ubiquitous in health care settings, scientists are increasingly turning to electronic-based recruitment methods to encourage participation in clinical trials.

21 Sep 2020

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

A collaborative team between the University of Minnesota Medical School and Van Andel Institute will soon begin a $6.2 million study that seeks to define the molecular linkages between aging and Parkinson's disease -- an approach for new treatment targets not yet explored by many researchers.

21 Sep 2020

Innovative approach for identifying new molecules to help track progression of Parkinson's

For many of the 200,000 patients diagnosed with Parkinson's disease in the United States every year, the diagnosis often occurs only after the appearance of severe symptoms such as tremors or speech difficulties.

21 Sep 2020

Study finds cardiac involvement in MIS-C is associated with myocardial injury

Using sensitive parameters to assess cardiac function, researchers at Children's Hospital of Philadelphia (CHOP) have found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) differs from Kawasaki disease (KD) and is associated with myocardial injury.

21 Sep 2020

Early bedtime helps people with diabetes lead a healthy, active lifestyle

Conducted by the University of Leicester and the University of South Australia, the study assessed the bedtime preferences (sleep chronotypes) of people with type 2 diabetes, identifying a connection between bedtimes and healthy, active lifestyles.

21 Sep 2020

BU researchers find how SARS-CoV-2 infection may drive deadly lung inflammation

Responding to the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2, requires models that can duplicate disease development in humans, identify potential targets and enable drug testing.

21 Sep 2020

Biomarker for earlier diagnosis of neurodegenerative diseases detected in the eye

A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.

21 Sep 2020

Study reports a drop in Medicare reimbursement rates for orthopedic trauma surgery

The amount Medicare reimburses for orthopedic trauma surgery has fallen by nearly one-third over the past two decades, reports a study in the Journal of Orthopaedic Trauma.

21 Sep 2020

New discovery of an interaction between sensory neurons and immune cells

Pain is a protective mechanism, alerting us to danger by generating an unpleasant sensation. The warning message is carried to the spinal cord by specialized sensory neurons, which are intertwined with other sensory and motor neurons in peripheral nerves.

21 Sep 2020

Flu vaccine does not increase a person's COVID-19 risk, finds study

A new Cleveland Clinic study has found that receiving the influenza vaccine does not increase a person's risk for contracting COVID-19 or worsen associated morbidity or mortality.

21 Sep 2020

Black breast cancer patients experience more delays in treatment initiation, duration than white women

One in seven black women with breast cancer had delays in starting treatment, and black women also had extended duration of treatment, according to a study led by UNC Lineberger Comprehensive Cancer Center researchers.

21 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

Initial clinical guidelines for mechanical ventilation of COVID-19 patients suggested following standard approaches used in the treatment of acute respiratory distress syndrome (ARDS), which is characterized by rapid onset of widespread inflammation in the lungs.

21 Sep 2020

Medical Research News

Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

A cost-effective scalable production of SARS-CoV-2 RBD in yeast

Targeted therapy improves disease-free survival in patients with early-stage NSCLC

Machine-learning algorithm can detect early, subtle signs of osteoarthritis

Research underlines SARS-CoV-2 N-terminal domain of Nsp1 as a potential drug target

CABI scientists highlight COVID-19 implications on food security in Kenya and Uganda

Oncology nurses should be routinely tested for SARS-CoV-2, warn researchers

Study finds how different strategies may impact clinical trial enrollment

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

Innovative approach for identifying new molecules to help track progression of Parkinson's

Study finds cardiac involvement in MIS-C is associated with myocardial injury

Early bedtime helps people with diabetes lead a healthy, active lifestyle

BU researchers find how SARS-CoV-2 infection may drive deadly lung inflammation

Biomarker for earlier diagnosis of neurodegenerative diseases detected in the eye

Study reports a drop in Medicare reimbursement rates for orthopedic trauma surgery

New discovery of an interaction between sensory neurons and immune cells

Flu vaccine does not increase a person's COVID-19 risk, finds study

Black breast cancer patients experience more delays in treatment initiation, duration than white women

Research uncovers potential cause of neurotoxicity due to immunotherapy

Using computer simulations to examine personalized mechanical ventilation of COVID-19 patients

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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